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Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7382, pp. 463 - 468
Exercise benefits a variety of organ systems in mammals, and some of the best-recognized effects of exercise on muscle are mediated by the transcriptional... 
SKELETAL-MUSCLE | COACTIVATOR | PHOSPHORYLATION | PGC-1-ALPHA | MULTIDISCIPLINARY SCIENCES | DISEASE | MYOBLAST | EXPRESSION | EXERCISE | ADIPOSE-TISSUE | PROTECTS | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Adipocytes - drug effects | Obesity - blood | Adipose Tissue, White - cytology | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Models, Animal | Energy Metabolism - physiology | Intracellular Signaling Peptides and Proteins - genetics | Obesity - chemically induced | Mice, Transgenic | Trans-Activators - deficiency | Obesity - prevention & control | Plasma - chemistry | Adipose Tissue, Brown - drug effects | Exercise - physiology | Mice | Mice, Inbred BALB C | Transcription Factors | Energy Metabolism - drug effects | Thermogenesis - genetics | Adipose Tissue, White - metabolism | Adipocytes - cytology | Culture Media, Conditioned - pharmacology | Subcutaneous Fat - metabolism | Insulin Resistance - physiology | Cell Respiration - drug effects | Subcutaneous Fat - drug effects | Trans-Activators - genetics | Energy Metabolism - genetics | Gene Expression Regulation - genetics | Cells, Cultured | Hormones - secretion | Muscle Cells - metabolism | Physical Conditioning, Animal - physiology | Subcutaneous Fat - cytology | Gene Expression Regulation - drug effects | Adipose Tissue, Brown - cytology | Animals | Hormones - metabolism | Ion Channels - metabolism | Adipocytes - metabolism | Trans-Activators - secretion | Trans-Activators - metabolism | Adipose Tissue, Brown - metabolism | Thermogenesis - drug effects | Uncoupling Protein 1 | Adipose Tissue, White - drug effects
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2015, Volume 21, Issue 12, pp. 1497 - 1501
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20944
Background: Alterations in the composition of gut microbiota - known as dysbiosis - has been proposed to contribute to the development of obesity, thereby... 
BACTERIAL COMMUNITY | INSULIN | IN-VITRO | LIPID-METABOLISM | PLASMA | MECHANISM | LINOLEIC-ACID | GLUCOSE | MULTIDISCIPLINARY SCIENCES | LIVER | GUT MICROBIOTA | Intestines - drug effects | Obesity - diet therapy | Molecular Weight | Xylans - pharmacology | Diet - adverse effects | Cholesterol - blood | Body Weight - drug effects | Male | Linoleic Acids, Conjugated - metabolism | Obesity - microbiology | Metagenome - physiology | Bacterial Load - drug effects | Subcutaneous Fat - metabolism | Prevotella - physiology | Subcutaneous Fat - drug effects | Obesity - etiology | Bifidobacterium - physiology | Biomarkers - metabolism | Dietary Fats - adverse effects | Metagenome - drug effects | Mice, Inbred C57BL | Bacteroides - physiology | Insulin Resistance | Obesity - metabolism | Prebiotics | Gene Expression Regulation - drug effects | Animals | Intestines - microbiology | Xylans - chemistry | Xylans - therapeutic use | Mice | Triticum - chemistry | Microbiota (Symbiotic organisms) | Diet | Analysis | Body weight | Physiological aspects | Insulin resistance | Wheat | Fatty acids | Dysbacteriosis | Adipose tissue | Fat metabolism | Enzyme activity | Lipids | Glucose | Molecular weight | High fat diet | Proteins | Microbiota | Enzymatic activity | Rodents | Nutrients | Bacteria | Oxidation | Colon | Lipid metabolism | Supplementation | Arabinoxylans | Food | Carbohydrates | Obesity | Dietary supplements | Polymerization | Inflammation | Ecology | Metabolism | Fermentation | Gene expression | Insulin | Body weight gain | Cholesterol | Studies | Nutrition research | Correlation analysis | Laboratory animals
Journal Article
Diabetologia, ISSN 0012-186X, 2005, Volume 48, Issue 11, pp. 2365 - 2375
Aims/hypothesis Intake of n-3 polyunsaturated fatty acids reduces adipose tissue mass, preferentially in the abdomen. The more pronounced effect of... 
activated protein-kinase | linolenic acid | cpt-i | messenger-rna | gene-expression | coactivator pgc-1-alpha | metabolism | adipose-tissue | dietary fish-oil | obesity | Medicine | Mitochondria | Adipose tissue | n -3 Polyunsaturated fatty acids | PGC-1 | Flax-seed oil | Metabolism | Fish oil | PPARGC1A | Carnitine palmitoyltransferase 1 | n-3 Polyunsaturated fatty acids | ACTIVATED PROTEIN-KINASE | mitochondria | DIETARY FISH-OIL | fish oil | adipose tissue | LINOLENIC ACID | OBESITY | MESSENGER-RNA | carnitine palmitoyltransferase 1 | CPT-I | n-3 polyunsaturated fatty acids | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | flax-seed oil | COACTIVATOR PGC-1-ALPHA | ADIPOSE-TISSUE | Epididymis - metabolism | Carnitine O-Palmitoyltransferase - genetics | Trans-Activators - drug effects | Male | NF-E2-Related Factor 1 - genetics | Adipocytes - drug effects | Mitochondrial Proteins - drug effects | alpha-Linolenic Acid - pharmacology | Adipose Tissue - metabolism | Subcutaneous Fat - metabolism | Eicosapentaenoic Acid - pharmacology | Mitochondrial Proteins - metabolism | NF-E2-Related Factor 1 - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Subcutaneous Fat - drug effects | Trans-Activators - genetics | Carnitine O-Palmitoyltransferase - drug effects | Epididymis - drug effects | Oxidation-Reduction | Mice, Inbred C57BL | Cells, Cultured | Fatty Acids, Unsaturated - pharmacology | Mitochondria - metabolism | Fatty Acids, Unsaturated - metabolism | Mitochondria - drug effects | Gene Expression Regulation - drug effects | Docosahexaenoic Acids - pharmacology | Animals | Fatty Acids, Unsaturated - isolation & purification | Adipocytes - metabolism | Lipogenesis - drug effects | Obesity - prevention & control | Mice | Transcription Factors | Adipose Tissue - drug effects | Fish Oils - chemistry
Journal Article
Cell Metabolism, ISSN 1550-4131, 03/2016, Volume 23, Issue 3, pp. 427 - 440
Journal Article
Diabetes, ISSN 0012-1797, 05/2016, Volume 65, Issue 5, pp. 1164 - 1178
Increased visceral fat, rather than subcutaneous fat, during the onset of obesity is associated with a higher risk of developing metabolic diseases. The... 
WT1 Proteins - metabolism | Obesity, Morbid - surgery | Adipogenesis - drug effects | Humans | Middle Aged | WT1 Proteins - antagonists & inhibitors | Gene Expression Profiling | Intra-Abdominal Fat - cytology | Stilbenes - pharmacology | Subcutaneous Fat, Abdominal - cytology | RNA Interference | Tretinoin - metabolism | Receptors, Retinoic Acid - agonists | Intra-Abdominal Fat - drug effects | Adult Stem Cells - pathology | Obesity, Morbid - metabolism | WT1 Proteins - genetics | Gene Ontology | Adult Stem Cells - drug effects | Obesity, Morbid - pathology | Bariatric Surgery | Adult Stem Cells - cytology | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Receptors, Retinoic Acid - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | Down-Regulation - drug effects | Intra-Abdominal Fat - metabolism | Naphthalenes - pharmacology | Response Elements - drug effects | Subcutaneous Fat, Abdominal - drug effects | Up-Regulation - drug effects | Adult Stem Cells - metabolism | Subcutaneous Fat, Abdominal - pathology | Signal Transduction - drug effects | Active Transport, Cell Nucleus - drug effects | Benzoates - pharmacology | Intra-Abdominal Fat - pathology | Subcutaneous Fat, Abdominal - metabolism | Adipose tissues | Obesity | Complications and side effects | Stem cells | Metabolic diseases | Research | Risk factors | Tretinoin | Metabolism
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2016, Volume 24, Issue 6, pp. 820 - 834
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63623
Background: Lipoatrophy and/or central fat gain are observed frequently in patients on antiretroviral therapy (ART). Both are assumed to be antiretroviral... 
PROTEASE INHIBITOR | NUCLEOSIDE-SPARING REGIMEN | THYMIDINE ANALOG | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIAL-FUNCTION | HIV-1-INFECTED PATIENTS | INFECTED PATIENTS | RANDOMIZED COMPARATIVE TRIAL | BODY-COMPOSITION | HUMAN-IMMUNODEFICIENCY-VIRUS | LIMB FAT | HIV Protease Inhibitors - adverse effects | Torso | Adiposity - drug effects | Humans | Antiretroviral Therapy, Highly Active - adverse effects | Tomography, X-Ray Computed | Absorptiometry, Photon | Reverse Transcriptase Inhibitors - adverse effects | Drug-Related Side Effects and Adverse Reactions | Subcutaneous Fat - drug effects | Lipodystrophy - chemically induced | Intra-Abdominal Fat - drug effects | Lipodystrophy - diagnostic imaging | Complications and side effects | Highly active antiretroviral therapy | Care and treatment | Protease inhibitors | AIDS treatment | Proteases | DNA polymerases | Stavudine | Research | HIV (Viruses) | HIV infection | Antiretroviral drugs | Antiviral agents | RNA-directed DNA polymerase | Toxicity | Clinical trials | Proteinase inhibitors | Thymidine | Patients | Efavirenz | Antiretroviral therapy | Switching | Tenofovir | Side effects | Acquired immune deficiency syndrome--AIDS | Lipoatrophy | Antiretroviral agents | Nucleoside reverse transcriptase inhibitors | Human immunodeficiency virus--HIV | Abacavir | Lipodystrophy | Zidovudine | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article