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Angewandte Chemie International Edition, ISSN 1433-7851, 04/2017, Volume 56, Issue 15, pp. 4100 - 4109
Journal Article
European journal of organic chemistry, ISSN 1434-193X, 05/2018, Volume 2018, Issue 18, p. 2071
Journal Article
Tetrahedron letters, ISSN 0040-4039, 12/2017, Volume 58, Issue 52, p. 4855
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.tetlet.2017.11.033 An... 
Sulfonamides
Journal Article
Applied catalysis. B, Environmental, ISSN 0926-3373, 08/2017, Volume 210, p. 88
Display Omitted 
Sulfonamides
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 467, Issue 7315, pp. 596 - 599
B-RAF is the most frequently mutated protein kinase in human cancers(1). The finding that oncogenic mutations in BRAF are common in melanoma(2), followed by... 
ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | MUTATION | KERATOACANTHOMAS | SENSITIVITY | SENESCENCE | SORAFENIB | HUMAN CANCER | PROGRESSION | BRAF(V600E) | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Macaca fascicularis | Melanoma - enzymology | Substrate Specificity | Positron-Emission Tomography | Extracellular Signal-Regulated MAP Kinases - metabolism | Indoles - administration & dosage | Neoplasm Metastasis | Melanoma - genetics | Phosphorylation - drug effects | Mutant Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Sulfonamides - chemistry | Mutant Proteins - genetics | Models, Molecular | Rats | Mutant Proteins - metabolism | Melanoma - pathology | Mutation - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Indoles - adverse effects | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Mutant Proteins - chemistry | Alleles | Dogs | Sulfonamides - adverse effects | Indoles - therapeutic use | Indoles - chemistry | Sulfonamides - administration & dosage | Control | Gene mutations | Melanoma | Development and progression | Genetic aspects | Research | Health aspects | Protein kinases | Cancer | Proteins | Mutation | Kinases | Rodents | Index Medicus | targeted therapy | melanoma | BRAF | PLX4032 | biomarker | oncogene
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2012, Volume 30, Issue 5, pp. 488 - 496
Purpose BCL2 overexpression is a hallmark of chronic lymphocytic leukemia (CLL). The novel BH3 mimetic navitoclax (ABT-263) specifically inhibits BCL2 and... 
APOPTOSIS | LYMPHOMA-CELLS | ANTAGONIST ABT-737 | ONCOLOGY | SENSITIVITY | RESISTANCE | BH3 MIMETIC ABT-737 | CANCER | CHEMOTHERAPY | CELL-DEATH | FAMILY | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Antineoplastic Agents - administration & dosage | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Antineoplastic Agents - adverse effects | Biomarkers, Tumor - metabolism | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Aniline Compounds - administration & dosage | Chromosome Deletion | Proto-Oncogene Proteins - metabolism | Aniline Compounds - pharmacology | Drug Administration Schedule | Administration, Oral | In Situ Hybridization, Fluorescence | Treatment Outcome | Thrombocytopenia - chemically induced | Aniline Compounds - pharmacokinetics | Sulfonamides - pharmacology | Sulfonamides - pharmacokinetics | Apoptosis Regulatory Proteins - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Sulfonamides - adverse effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Aniline Compounds - adverse effects | Sulfonamides - administration & dosage | Hema7 | ORIGINAL REPORTS
Journal Article
The lancet oncology, ISSN 1470-2045, 2010, Volume 11, Issue 12, pp. 1149 - 1159
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2008, Volume 349, Issue 1, pp. 300 - 313
Journal Article
Journal of enzyme inhibition and medicinal chemistry, ISSN 1475-6374, 2017, Volume 32, Issue 1, pp. 1071 - 1078
Journal Article