X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6020) 6020
Book Review (565) 565
Publication (469) 469
Magazine Article (29) 29
Conference Proceeding (21) 21
Book Chapter (16) 16
Book / eBook (5) 5
Data Set (1) 1
Dissertation (1) 1
Government Document (1) 1
Paper (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (5505) 5505
humans (3997) 3997
male (3330) 3330
animals (2290) 2290
sildenafil citrate (2115) 2115
sulfones (1945) 1945
sulfones - pharmacology (1705) 1705
female (1690) 1690
middle aged (1423) 1423
adult (1275) 1275
sildenafil (1190) 1190
sulfones - therapeutic use (1111) 1111
piperazines - therapeutic use (1102) 1102
rats (1081) 1081
purines (1044) 1044
aged (983) 983
pharmacology & pharmacy (894) 894
piperazines - pharmacology (852) 852
urology & nephrology (717) 717
erectile dysfunction - drug therapy (677) 677
erectile dysfunction (671) 671
sulfones - administration & dosage (637) 637
mice (632) 632
abridged index medicus (597) 597
treatment outcome (591) 591
piperazines - administration & dosage (541) 541
membranes, artificial (532) 532
sulfones - adverse effects (527) 527
dose-response relationship, drug (522) 522
phosphodiesterase inhibitors - therapeutic use (508) 508
purines - therapeutic use (488) 488
piperazines - adverse effects (461) 461
double-blind method (454) 454
sulfones - chemistry (444) 444
impotence (438) 438
rats, sprague-dawley (433) 433
analysis (432) 432
polymers (427) 427
vasodilator agents - therapeutic use (415) 415
nitric-oxide (412) 412
cardiac & cardiovascular systems (408) 408
phosphodiesterase inhibitors - pharmacology (408) 408
purines - pharmacology (408) 408
time factors (392) 392
administration, oral (363) 363
drug therapy (354) 354
expression (347) 347
blood pressure - drug effects (342) 342
nitric oxide (334) 334
hypertension (333) 333
vardenafil dihydrochloride (317) 317
disease models, animal (315) 315
research (314) 314
hypertension, pulmonary - drug therapy (304) 304
rats, wistar (291) 291
rofecoxib (284) 284
care and treatment (282) 282
lactones - adverse effects (282) 282
nonsteroidal antiinflammatory drugs (278) 278
purines - administration & dosage (273) 273
in-vitro (271) 271
men (270) 270
risk factors (269) 269
vasodilator agents - pharmacology (268) 268
activation (263) 263
aged, 80 and over (262) 262
biochemistry & molecular biology (262) 262
medicine, general & internal (262) 262
celecoxib (259) 259
inflammation (259) 259
sulfones - pharmacokinetics (258) 258
pulmonary hypertension (254) 254
therapy (251) 251
prospective studies (249) 249
cross-over studies (248) 248
sulfones - blood (245) 245
health aspects (243) 243
physiology (240) 240
pharmacokinetics (239) 239
oral sildenafil (237) 237
hemodialysis (236) 236
lactones - therapeutic use (234) 234
phosphodiesterase inhibitors - adverse effects (234) 234
vasodilator agents - administration & dosage (234) 234
medicine & public health (233) 233
drug therapy, combination (231) 231
adolescent (229) 229
oxidative stress (229) 229
cells, cultured (228) 228
renal dialysis - instrumentation (227) 227
efficacy (226) 226
inhibition (226) 226
peripheral vascular disease (225) 225
surgery (223) 223
engineering, biomedical (221) 221
double-blind (219) 219
guanidines - pharmacology (216) 216
toxicology (216) 216
article (214) 214
apoptosis (213) 213
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5872) 5872
German (38) 38
French (33) 33
Russian (28) 28
Chinese (26) 26
Japanese (16) 16
Polish (9) 9
Spanish (9) 9
Italian (8) 8
Czech (4) 4
Croatian (3) 3
Portuguese (3) 3
Bulgarian (2) 2
Dutch (2) 2
Bosnian (1) 1
Hebrew (1) 1
Korean (1) 1
Norwegian (1) 1
Persian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 12/2007, Volume 5, Issue 12, pp. 2376 - 2385
Background:  Selective inhibitors of cyclooxygenase‐2 (COX‐2) called coxibs, are effective anti‐inflammatory and analgesic drugs. Recently, these drugs were... 
thromboxane | coxibs | thrombin generation | prostacyclin | NSAID | platelet activation | Thrombin generation | Prostacyclin | Platelet activation | Thromboxane | Coxibs | MASS-SPECTROMETRY | CYCLOOXYGENASES | ANTIPLATELET | THROMBOMODULIN | CLOPIDOGREL | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | IONIZATION | TISSUE FACTOR | Humans | Naproxen - pharmacology | Sulfones - adverse effects | Male | Reference Values | Blood Platelets - enzymology | Sulfones - pharmacology | Prostaglandins - blood | Lactones - pharmacology | Phospholipases A - blood | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Cyclooxygenase 2 - blood | Time Factors | Prostaglandins - urine | Pyrazoles - blood | Antigens, Neoplasm - blood | Adult | Platelet Aggregation - drug effects | Cyclooxygenase 2 Inhibitors - blood | Blood Platelets - drug effects | Sulfones - blood | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Thrombomodulin - blood | Naproxen - adverse effects | Cyclic AMP - blood | Cyclooxygenase 2 Inhibitors - pharmacology | Double-Blind Method | Celecoxib | Lactones - adverse effects | Cell Adhesion - drug effects | Naproxen - blood | Sulfonamides - pharmacology | Thromboxanes - blood | Thromboxanes - urine | Blood Platelets - metabolism | Fibrinogen - metabolism | P-Selectin - blood | Sulfonamides - adverse effects | Leukocytes - drug effects | Platelet Activation - drug effects | Thrombin - metabolism | Platelet Membrane Glycoprotein IIb - blood | Physiological aspects | Prothrombin | COX-2 inhibitors | Thrombin | Analysis | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2012, Volume 130, Issue 6, pp. 1357 - 1366
The MET oncogene is amplified in a fraction of human gastric carcinoma cell lines, with consequent overexpression and constitutive activation of the... 
oncogene addiction | surrogate biomarkers | targeted therapies | Met receptor | CARCINOMA CELLS | NECROSIS-FACTOR-ALPHA | PLASMINOGEN-ACTIVATOR RECEPTOR | INTERLEUKIN-8 | IN-VITRO | ONCOLOGY | AUTOCRINE GROWTH-FACTOR | C-MET | PROSTATE-CANCER | UROKINASE RECEPTOR | CELL-LINE | Mannose-Binding Lectins - metabolism | Proto-Oncogene Proteins c-met - metabolism | Interleukin-8 - genetics | Membrane Glycoproteins - metabolism | Humans | Stomach Neoplasms - metabolism | Chemokine CXCL1 - genetics | Gene Expression Profiling | Sulfones - pharmacology | Interleukin-6 - blood | Biomarkers, Tumor - metabolism | Female | Indoles - pharmacology | Interleukin-8 - metabolism | Chemokine CXCL1 - metabolism | Interleukin-8 - blood | Interleukin-6 - metabolism | Stomach Neoplasms - genetics | Interleukin-6 - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Membrane Glycoproteins - blood | Receptors, Cell Surface - metabolism | Receptors, Cell Surface - blood | Chemokine CXCL1 - blood | Stomach Neoplasms - drug therapy | Membrane Glycoproteins - genetics | Proto-Oncogene Proteins c-met - genetics | Biomarkers, Tumor - blood | Xenograft Model Antitumor Assays | Animals | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - blood | Stomach Neoplasms - blood | Mice, Nude | Proteomics | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Receptors, Cell Surface - genetics | Biomarkers | Kinases | Gene expression | Tumors | Index Medicus
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 04/2016, Volume 124, Issue 4, pp. 437 - 444
Bisphenol A (BPA) is a high-production-volume chemical associated with a wide range of health outcomes in animal and human studies. BPA is used as a developer... 
North Carolina | Sulfones - urine | Humans | Middle Aged | Male | Benzhydryl Compounds - blood | Phenols - urine | Benzhydryl Compounds - urine | Occupational Exposure - analysis | Adult | Female | Paper | Phenols - blood | Aged | Sulfones - blood | Index Medicus | Research
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2006, Volume 20, Issue 3, pp. 542 - 544
It is widely believed that the potencies of nonsteroid anti-inflammatory drugs ( NSAIDs) as inhibitors of cyclooxygenase ( COX) are influenced by protein... 
SITE | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | nonsteroid anti-inflammatory drugs | coxibs | PROSTAGLANDIN H-2 SYNTHASE | CELL BIOLOGY | CYCLO-OXYGENASE-2 | THERAPY | FLUID | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGY | prostaglandins | SELECTIVITY | Organic Chemicals - cerebrospinal fluid | Humans | Naproxen - pharmacology | Synovial Fluid - metabolism | Pyrazoles - cerebrospinal fluid | Sodium Salicylate - pharmacology | Lactones - pharmacology | Aspirin - cerebrospinal fluid | Cell Line - drug effects | Calcium - physiology | Pyrazoles - blood | Organic Chemicals - pharmacology | Dinoprostone - cerebrospinal fluid | Diclofenac - cerebrospinal fluid | Aspirin - pharmacology | Sulfones - cerebrospinal fluid | Aspirin - blood | Thiazines - blood | Sulfonamides - pharmacology | Indomethacin - cerebrospinal fluid | Indomethacin - pharmacology | Cyclooxygenase 1 - drug effects | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - blood | Diclofenac - pharmacology | Thiazoles - blood | Thromboxane A2 - blood | Cerebrospinal Fluid Proteins - pharmacology | Dinoprostone - biosynthesis | Lactones - cerebrospinal fluid | Blood Platelets - enzymology | Cyclooxygenase 2 Inhibitors - cerebrospinal fluid | Sodium Salicylate - cerebrospinal fluid | Sulfones - pharmacology | Blood Proteins - pharmacology | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Naproxen - cerebrospinal fluid | Sodium Salicylate - blood | Thiazines - pharmacology | Cyclooxygenase 2 Inhibitors - blood | Cyclooxygenase Inhibitors - cerebrospinal fluid | Blood Platelets - drug effects | Sulfones - blood | Organic Chemicals - blood | Ionophores - pharmacology | Pyrazoles - pharmacology | Sulfonamides - cerebrospinal fluid | Cyclooxygenase 2 Inhibitors - pharmacology | Thiazoles - cerebrospinal fluid | Celecoxib | Diclofenac - blood | Dinoprostone - blood | Naproxen - blood | Organ Specificity | Calcimycin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Indomethacin - blood | Protein Binding | Thiazines - cerebrospinal fluid | Thiazoles - pharmacology | Index Medicus
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 11/2013, Volume 9, Issue 11, pp. 8851 - 8863
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2013, Volume 64, pp. 114 - 123
Previous studies have demonstrated that cognitive function can be restored in mouse models of Alzheimer's disease (AD) following administration of sildenafil,... 
PDE5 | Tadalafil | Alzheimer's disease | Memory | Blood–brain barrier | Blood-brain barrier | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES | ALZHEIMERS-DISEASE | MEMORY DEFICITS | GLYCOGEN-SYNTHASE KINASE-3 | CGMP-BINDING | NEUROSCIENCES | MESSENGER-RNA | AMYLOID-BETA | NITRIC-OXIDE | OBJECT RECOGNITION | PHARMACOLOGY & PHARMACY | TRANSGENIC MICE | Gene Expression Regulation, Enzymologic - drug effects | Sulfones - therapeutic use | Species Specificity | Nootropic Agents - metabolism | Humans | Half-Life | Macaca fascicularis | Male | Carbolines - metabolism | Phosphodiesterase 5 Inhibitors - pharmacokinetics | Brain - metabolism | Sildenafil Citrate | Tissue Distribution | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Phosphodiesterase 5 Inhibitors - metabolism | Female | Phosphodiesterase 5 Inhibitors - therapeutic use | Purines - therapeutic use | Carbolines - blood | Carbolines - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Disease Models, Animal | Phosphodiesterase 5 Inhibitors - blood | Mice, Inbred C57BL | Nootropic Agents - pharmacokinetics | Alzheimer Disease - drug therapy | Nootropic Agents - therapeutic use | Mice, Transgenic | Piperazines - therapeutic use | Nootropic Agents - blood | Blood-Brain Barrier - metabolism | Brain - drug effects | Animals | Alzheimer Disease - metabolism | Brain - pathology | Cyclic Nucleotide Phosphodiesterases, Type 5 - genetics | Mice | Carbolines - pharmacokinetics | Alzheimer Disease - genetics | Neurosciences | Messenger RNA | Analysis | Smart drugs and nutrients | Universities and colleges | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 39, pp. 17017 - 17022
Chronic administration of high levels of selective COX-2 inhibitors (coxibs), particularly rofecoxib, valdecoxib, and parecoxib, increases risk for... 
Metabolomics | Blood coagulation | Metabolites | Coagulation | Mice | Platelet aggregation | Bleeding time | Platelets | Blood | Blood plasma | Eicosanoids | Coxib | Vioxx | Cardiovascular side effect | coxib | MULTIDISCIPLINARY SCIENCES | ENDOTHELIUM-DEPENDENT VASOCONSTRICTOR | 20-HYDROXYEICOSATETRAENOIC ACID | RISK | TOXICITY | INCREASED PLATELET AGGREGABILITY | CORONARY HEART-DISEASE | 20-HETE CONTRIBUTES | eicosanoids | metabolomics | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | cardiovascular side effect | ACUTE MYOCARDIAL-INFARCTION | EPOXIDE HYDROLASE INHIBITORS | Cyclooxygenase 2 Inhibitors - administration & dosage | Mice, Inbred C57BL | Sulfones - adverse effects | Male | Biomarkers - blood | Lactones - adverse effects | Hydroxyeicosatetraenoic Acids - blood | Cyclooxygenase 2 Inhibitors - adverse effects | Animals | Blood Coagulation - drug effects | Hydroxyeicosatetraenoic Acids - pharmacology | Lactones - administration & dosage | Cardiovascular Diseases - blood | Bleeding Time | Cardiovascular Diseases - chemically induced | Platelet Aggregation - drug effects | Blood Platelets - drug effects | Cardiovascular Diseases - diagnosis | Sulfones - administration & dosage | Metabonomic analysis | COX-2 inhibitors | Care and treatment | Physiological aspects | Dosage and administration | Research | Cardiovascular diseases | Biological markers | Methods | Biomarkers | Cardiovascular disease | Pharmacology | Nonsteroidal anti-inflammatory drugs | Rodents | Risk factors | Index Medicus | Animal models | biomarkers | Oral administration | Data processing | Bleeding | Clotting | Blood levels | Cost-benefit analysis | rofecoxib | Cytochromes | Cyclooxygenase-2 | Biological Sciences
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 03/2019, Volume 175, pp. 586 - 595
Journal Article
Journal Article