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Drug Metabolism and Disposition, ISSN 0090-9556, 07/2012, Volume 40, Issue 7, pp. 1366 - 1379
The transcription factors aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), pregnane X receptor (PXR), peroxisome proliferator-activated... 
TRANSCRIPTION FACTORS | PRIMARY HUMAN HEPATOCYTES | ANTIOXIDANT RESPONSE ELEMENT | MESSENGER-RNA EXPRESSION | CONSTITUTIVE ANDROSTANE RECEPTOR | BILIARY-EXCRETION | PROLIFERATOR-ACTIVATED RECEPTOR | MOUSE-LIVER | PHARMACOLOGY & PHARMACY | MICROSOMAL-ENZYME INDUCERS | PREGNANE-X-RECEPTOR | Inactivation, Metabolic | Receptors, Steroid - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | NAD(P)H Dehydrogenase (Quinone) - genetics | Organic Anion Transporters - metabolism | Glucuronosyltransferase - genetics | Organic Anion Transporters - genetics | Glutathione Transferase - genetics | Receptors, Aryl Hydrocarbon - metabolism | Female | NF-E2-Related Factor 2 - genetics | Sulfotransferases - metabolism | Aldehyde Dehydrogenase - metabolism | Sulfotransferases - genetics | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Receptors, Aryl Hydrocarbon - genetics | Glutathione Transferase - metabolism | Aldehyde Dehydrogenase - genetics | PPAR alpha - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | Mice, Knockout | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Animals | Glucuronosyltransferase - metabolism | Receptors, Steroid - genetics | NF-E2-Related Factor 2 - metabolism | Cytochrome P-450 Enzyme System - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | PPAR alpha - metabolism | Multidrug Resistance-Associated Proteins | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 2, pp. 193 - 203
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 03/2010, Volume 17, Issue 1, pp. 17 - 25
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e106774 - e106774
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11524 - 11529
Neuronal development is the result of a multitude of neural migrations, which require extensive cell-cell communication. These processes are modulated by... 
Enzymes | Phenotypes | Neurons | Medical genetics | Ligands | Sulfates | Genetic mutation | Kallmann syndrome | Human genetics | Hypogonadism | Heparan sulfotransferase | SPECIFICITY | GONADOTROPIN-RELEASING-HORMONE | MULTIDISCIPLINARY SCIENCES | DEFICIENCY | FGF RECEPTOR | FAMILY | heparan sulfotransferase | CAENORHABDITIS-ELEGANS | KALLMANN-SYNDROME | MUTATIONS | EXPRESSION | HEPARAN-SULFATE 6-O-SULFOTRANSFERASE | Species Specificity | Humans | Middle Aged | Genes, Helminth | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Kallmann Syndrome - enzymology | Male | Mutation, Missense | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Sulfotransferases - deficiency | Intercellular Signaling Peptides and Proteins - metabolism | Receptors, Fibroblast Growth Factor - genetics | Adult | Female | Sulfotransferases - metabolism | Child | Extracellular Matrix Proteins - metabolism | Sulfotransferases - genetics | Amino Acid Sequence | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Kallmann Syndrome - genetics | Extracellular Matrix Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Models, Molecular | Nerve Tissue Proteins - genetics | Hypogonadism - enzymology | Hypogonadism - genetics | Nerve Tissue Proteins - metabolism | Sequence Homology, Amino Acid | Animals | Pedigree | Receptors, Fibroblast Growth Factor - metabolism | Mutation | In Vitro Techniques | Caenorhabditis elegans Proteins - genetics | Sulfotransferases - chemistry | Amino Acid Substitution | Index Medicus | Heparan sulfate | Fibroblast growth factor | Puberty | Intercellular signalling | Polysaccharides | Hedgehog protein | Infertility | Extracellular matrix | Gonadotropin-releasing hormone | Cell migration | Sugar | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e67040 - e67040
Background: Genomic deletion at tumor suppressor loci is a common genetic aberration in human cancers. The study aimed to explore candidate tumor suppressor... 
PATHOGENESIS | ISOZYMES | MOLECULAR MARKERS | INSTABILITY | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | PATTERNS | HEPARAN-SULFATE PROTEOGLYCANS | CARCINOMA | DELETIONS | SULFOTRANSFERASE | Sulfotransferases - genetics | Intestinal Mucosa - metabolism | Prognosis | Membrane Proteins - genetics | Colorectal Neoplasms - genetics | Down-Regulation | Humans | Middle Aged | Genetic Loci - genetics | Male | Chromosomes, Human, Pair 4 - genetics | Colorectal Neoplasms - diagnosis | Sulfotransferases - deficiency | Membrane Proteins - deficiency | Colonic Polyps - genetics | Alleles | Aged, 80 and over | Adult | Female | Aged | Colorectal Neoplasms - pathology | Neoplasm Staging | Genes, Tumor Suppressor | Gene Expression Regulation, Neoplastic - genetics | RNA | Analysis | Oncology, Experimental | Genes | Colorectal cancer | Genetic aspects | Genetic transcription | Research | Tumors | Cancer | Biotechnology | DNA polymerase | Laboratories | Epithelial cells | Colorectal carcinoma | Reverse transcription | Biosynthesis | Metastasis | Tissues | Clonal deletion | Surgery | Deletion | Bioindicators | Chromosomes | Deoxyribonucleic acid--DNA | Heparan sulfate | Microsatellites | Tumor cells | Chromosome deletion | Chromosome 4 | Gene expression | Ribonucleic acid--RNA | Loci | Heterozygosity | Medicine | Polymerase chain reaction | Genetic markers | Hospitals | Medical prognosis | Loss of heterozygosity | Biomarkers | Tumor suppressor genes | Mutation | Aberration | Gene mapping | Index Medicus | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 06/2015, Volume 234, pp. 309 - 319
Estrogens have important roles in the pathogenesis of endometrial cancer. They can have carcinogenic effects through stimulation of cell proliferation or... 
Aromatase pathway | Sulfatase pathway | Phase I and phase II estrogen metabolism | Aldo–keto reductase 1C3 (AKR1C3) | 17β-Hydroxysteroid dehydrogenases (17β-HSDs, HSD17B) | Catechol-O-methyl transferase (COMT) | 17b-Hydroxysteroid dehydrogenases | (17b-HSDs HSD17B)Aldoketo reductase 1C3 (AKR1C3) | 17 beta-Hydroxysteroid dehydrogenases (17 beta-HSDs, HSD17B) | DEHYDROGENASES | QUINONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGESTERONE ACTION | 17-BETA-ESTRADIOL | CARCINOGENESIS | OVARIAN ENDOMETRIOSIS | Aldo-keto reductase 1C3 (AKR1C3) | ENZYMES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PHASE-I | CARCINOMA | PRE-RECEPTOR REGULATION | Sulfatases - genetics | Progesterone Reductase - metabolism | Humans | Endometrial Neoplasms - metabolism | Aromatase - metabolism | Catechol O-Methyltransferase - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Androstenedione - metabolism | Catechol O-Methyltransferase - metabolism | Aromatase - genetics | Endometrial Neoplasms - genetics | Sulfatases - metabolism | Estrogens - genetics | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Sulfotransferases - metabolism | Estrogens - metabolism | Quinones - pharmacology | Glutathione S-Transferase pi - genetics | Sulfotransferases - genetics | Estrone - genetics | Quinone Reductases - metabolism | Androstenedione - genetics | Glutathione S-Transferase pi - metabolism | Estrogens - biosynthesis | RNA, Messenger - genetics | Transcriptome - genetics | Progesterone Reductase - genetics | Arylsulfotransferase - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Estrone - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | Estrone - metabolism | Cell Line, Tumor | Quinone Reductases - genetics | 3-Hydroxysteroid Dehydrogenases - genetics | Arylsulfotransferase - metabolism | Physiological aspects | Endometrial cancer | Sulfates | Genes | Estrogen | Steroids | Index Medicus
Journal Article
P L o S Genetics (Print), ISSN 1553-7390, 04/2011, Volume 7, Issue 4, pp. e1002025 - e1002025
textabstractDehydroepiandrosterone sulphate (DHEAS) is the most abundant circulating steroid secreted by adrenal glands-yet its function is unknown. Its serum... 
POLYCYSTIC-OVARY-SYNDROME | DEHYDROEPIANDROSTERONE-SULFATE LEVELS | RISK LOCI | BONE-MINERAL DENSITY | XENOBIOTIC METABOLISM | INSULIN-RESISTANCE | ACID-METABOLISM | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | CARDIOVASCULAR-DISEASE | GENOME-WIDE ASSOCIATION | Cytochrome P-450 CYP2C9 | Homeodomain Proteins - metabolism | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Actin-Related Protein 2-3 Complex - genetics | Male | Young Adult | Actin-Related Protein 2-3 Complex - metabolism | Aging - genetics | Bcl-2-Like Protein 11 | Kruppel-Like Transcription Factors - metabolism | Apoptosis Regulatory Proteins - genetics | Adult | Female | Sulfotransferases - metabolism | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Sulfotransferases - genetics | European Continental Ancestry Group - genetics | Gene Expression | Genome-Wide Association Study | Membrane Proteins - genetics | Liver - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Dehydroepiandrosterone Sulfate - blood | Homeodomain Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Linkage Disequilibrium | Aging - blood | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - genetics | Aged | Polymorphism, Single Nucleotide | Adaptor Proteins, Signal Transducing - metabolism | Kruppel-Like Transcription Factors - genetics | Physiological aspects | Aging | Dehydroepiandrosterone | Research | Single nucleotide polymorphisms | Gene expression | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Mens health | Womens health | Mortality | Men | Technological change | Genomes | Lymphomas | Diabetes | Metabolism | Age
Journal Article
The Plant Journal, ISSN 0960-7412, 07/2012, Volume 71, Issue 2, pp. 194 - 204
Pattern‐triggered immunity (PTI) is triggered by recognition of elicitors called microbe‐associated molecular patterns (MAMPs). Although immune responses may... 
Arabidopsis thaliana | pattern‐triggered immunity | microbe‐associated molecular pattern | phytosulfokine | receptor‐like protein kinase | PSKR | pattern-triggered immunity | microbe-associated molecular pattern | receptor-like protein kinase | DEFENSE RESPONSES | ARABIDOPSIS-THALIANA | SYSTEMIC ACQUIRED-RESISTANCE | PLANT SCIENCES | RICH REPEAT RECEPTOR | MOLECULAR-PATTERNS | TYROSYLPROTEIN SULFOTRANSFERASE | RECOGNITION RECEPTORS | MESOPHYLL-CELLS | DISEASE RESISTANCE | INNATE IMMUNITY | Arabidopsis - physiology | Plant Diseases - immunology | Arabidopsis - immunology | Plant Roots - genetics | Seedlings - genetics | Seedlings - microbiology | Plant Diseases - microbiology | Peptide Hormones - genetics | Arabidopsis Proteins - metabolism | Peptide Hormones - metabolism | Plant Roots - physiology | Intercellular Signaling Peptides and Proteins - metabolism | Seedlings - immunology | Plants, Genetically Modified | Flagellin - metabolism | Sulfotransferases - metabolism | Plant Proteins - metabolism | Pseudomonas syringae - physiology | Sulfotransferases - genetics | Arabidopsis Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Cell Communication | Gene Expression Regulation, Plant - genetics | Receptors, Cell Surface - metabolism | Plant Immunity - physiology | RNA, Plant - genetics | Plant Roots - microbiology | Plant Leaves - immunology | Arabidopsis - genetics | Arabidopsis - microbiology | Plant Proteins - genetics | DNA, Bacterial - genetics | Plant Leaves - genetics | Seedlings - physiology | Plant Roots - immunology | Signal Transduction - physiology | Mutagenesis, Insertional | Plant Leaves - microbiology | Plant Leaves - physiology | Receptors, Cell Surface - genetics | Enzymes | Anopheles | Messenger RNA | Chorionic gonadotropin | Plant physiology | Analysis | Cholecystokinin | Sulfates | Gene expression | Protein kinases | Plant biology | Signal transduction | Peptides | Plant growth | Index Medicus
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 01/2008, Volume 86, Issue 1, pp. 3 - 14
Selection of B cells subjected to hypermutation in germinal centres (GC) during T cell‐dependent (TD) antibody responses yields memory cells and long‐lived... 
axon | T‐dependent | germinal centre | B cell memory | T-dependent | Germinal centre | Axon | PLASMA-CELL | IV SEMAPHORIN CD100 | IMMUNOLOGY | CELL BIOLOGY | INVASIVE GROWTH | NEURITE OUTGROWTH | IN-VIVO | NONREDUNDANT ROLES | ANTIBODY-RESPONSES | SCATTER-FACTOR | PRIMARY IMMUNE-RESPONSE | TRANSGENIC MICE | Sulfotransferases | Antigens, T-Independent - immunology | Oligonucleotide Array Sequence Analysis | Cytoskeletal Proteins - genetics | Germinal Center - immunology | Humans | B-Lymphocyte Subsets - cytology | Axons - physiology | Lymphocyte Cooperation - genetics | Lymphocyte Cooperation - immunology | Hedgehog Proteins - genetics | B-Lymphocyte Subsets - immunology | Gene Rearrangement, B-Lymphocyte | Germinal Center - cytology | Transcription Factors - immunology | Leukemia, Lymphoid - genetics | Calmodulin-Binding Proteins - genetics | Nerve Tissue Proteins - immunology | Gene Expression Regulation - immunology | Calmodulin-Binding Proteins - immunology | Nerve Growth Factors - immunology | Transcription Factors - genetics | Organ Specificity | Nerve Tissue Proteins - genetics | Animals | Cytoskeletal Proteins - immunology | T-Lymphocytes - cytology | Nerve Growth Factors - genetics | Antigens, T-Independent - genetics | Immunologic Memory | T-Lymphocytes - immunology | Mice | Hedgehog Proteins - immunology | Leukemia, Lymphoid - immunology | Cytoskeletal Proteins, genetics | Intracellular Signaling Peptides and Proteins, metabolism | Up-Regulation | Spleen, cytology | Molecular Chaperones, metabolism | Membrane Proteins, metabolism | Germinal Center, physiology | Hedgehog Proteins, metabolism | Gene Expression Profiling | Spleen, metabolism | Sulfotransferases, genetics | Gene Expression, physiology | Sulfotransferases, metabolism | Heat-Shock Proteins, metabolism | GABA Plasma Membrane Transport Proteins, genetics | B-Lymphocytes, physiology | Germinal Center, metabolism | Membrane Proteins, genetics | RNA, Messenger, metabolism | Molecular Chaperones, genetics | Down-Regulation | B-Lymphocytes, metabolism | Reverse Transcriptase Polymerase Chain Reaction | Calmodulin-Binding Proteins, genetics | Calmodulin-Binding Proteins, metabolism | Cytoskeletal Proteins, metabolism | Nerve Tissue Proteins, genetics | GABA Plasma Membrane Transport Proteins, metabolism | Hedgehog Proteins, genetics | Intracellular Signaling Peptides and Proteins, genetics | Neurites, physiology | Nerve Tissue Proteins, metabolism | Heat-Shock Proteins, genetics | Index Medicus
Journal Article