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Cell Research, ISSN 1001-0602, 10/2018, Volume 28, Issue 10, pp. 963 - 964
Journal Article
NATURE, ISSN 0028-0836, 08/2018, Volume 560, Issue 7720, pp. 557 - 557
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 10/2014, Volume 20, Issue 10, pp. 1130 - 1137
Efforts to identify and annotate cancer driver genetic lesions have been focused primarily on the analysis of protein-coding genes; however, most genetic... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | APC DEFICIENCY | SMALL-INTESTINE | VARIANT | CELL BIOLOGY | SUPER-ENHANCERS | COLORECTAL-CANCER | PROSTATE-CANCER | MICE | MUTATIONS | EXPRESSION
Journal Article
Epigenomes, ISSN 2075-4655, 06/2019, Volume 3, Issue 2, p. 11
The spreading of epigenetic domains has emerged as a distinguishing epigenomic phenotype for diverse cell types. In particular, clusters of H3K27ac- and... 
epigenomics | pancreatic cancer | super-enhancers
Journal Article
NATURE METHODS, ISSN 1548-7091, 01/2015, Volume 12, Issue 1, pp. 71 - 78
High-throughput methods based on chromosome conformation capture have greatly advanced our understanding of the threedimensional (3D) organization of genomes... 
NUCLEAR-ORGANIZATION | ELEMENTS | HUMAN GENOME | LONG NONCODING RNAS | INTEGRATIVE ANNOTATION | SUPER-ENHANCERS | EMBRYONIC STEM-CELLS | HIGH-RESOLUTION | BIOCHEMICAL RESEARCH METHODS | CHROMOSOME CONFORMATION | TRANSCRIPTIONAL REGULATION
Journal Article
CELL, ISSN 0092-8674, 05/2018, Volume 173, Issue 6, pp. 1398 - 1398
Noncoding mutations in cancer genomes are frequent but challenging to interpret. PVT1 encodes an oncogenic lncRNA, but recurrent translocations and deletions... 
LONG NONCODING RNAS | SUPER-ENHANCERS | RANGE CHROMATIN INTERACTIONS | GENOME ARCHITECTURE | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | GENE-EXPRESSION | C-MYC | CANCER | FUSION GENES | CELL BIOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 07/2019, Volume 134, Issue 3, pp. 239 - 251
The oncogenic transcription factor TAL1 regulates the transcriptional program in T-ALL. ARID5B is one of the critical downstream targets of TAL1, which further... 
IDENTITY | TRANSLOCATION | REGULATOR | INHIBITION | LONG NONCODING RNAS | SUPER-ENHANCERS | GENETICS | MEDIATOR | TAL1 COMPLEX | HEMATOLOGY | INSIGHTS
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 07/2019, Volume 79, Issue 13, pp. 3479 - 3491
Recent studies suggest that targeting transcriptional machinery can lead to potent and selective anticancer effects in cancers dependent on high and constant... 
RNA-POLYMERASE-II | SUPER-ENHANCERS | ONCOLOGY | PHOSPHORYLATION | INITIATION | CDK7-DEPENDENT TRANSCRIPTIONAL ADDICTION | CANCER
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2019, Volume 75, Issue 5, pp. 905 - 920.e6
Variable levels of DNA methylation have been reported at tissue-specific differential methylation regions (DMRs) overlapping enhancers, including... 
dynamic DNA methylation | transcriptional heterogeneity | embryonic stem cells | super-enhancers | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2016, Volume 29, Issue 3, pp. 379 - 393
Journal Article
Science, ISSN 0036-8075, 06/2017, Volume 356, Issue 6344, pp. 1248 - +
Journal Article
RNA, ISSN 1355-8382, 11/2017, Volume 23, Issue 11, pp. 1729 - 1742
Super-enhancers are characterized by high levels of Mediator binding and are major contributors to the expression of their associated genes. They exhibit high... 
DATABASE | long-noncoding RNAs | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | logistic regression | transposable elements | triplex | EXPRESSION | MOTIF | super-enhancers
Journal Article