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1. Superantigens
: methods and protocols
by Brosnahan, Amanda J
2016, Methods in molecular biology, ISBN 9781493933440, Volume 1396.
This volume combines protocols that encompass the true variety of investigation done on superantigens in the fields of microbiology, immunology, molecular... 
Superantigens
Web Resource
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2. Full Text The bacterial superantigen and superantigen‐like proteins
by Fraser, John D and Proft, Thomas
Immunological Reviews, ISSN 0105-2896, 10/2008, Volume 225, Issue 1, pp. 226 - 243
The bacterial superantigens are protein toxins that bind to major histocompatibility complex class II and T‐cell receptor to stimulate large numbers of T... 
toxic shock | MHC | enterotoxin | TCR | superantigen | staphylococcus | Enterotoxin | Superantigen | Toxic shock | Staphylococcus | RECEPTOR BETA-CHAIN | IMMUNOLOGY | MITOGENIC EXOTOXIN-Z | MAMMARY-TUMOR VIRUS | COMPLETE GENOME SEQUENCE | STAPHYLOCOCCAL-ENTEROTOXIN-B | GROUP-A STREPTOCOCCUS | T-CELL-ACTIVATION | TOXIC-SHOCK-SYNDROME | POLYSPECIFIC IMMUNOGLOBULIN-G | MHC CLASS-II | Superantigens - toxicity | Receptors, Antigen, T-Cell - chemistry | Shock, Septic - etiology | Humans | Antigens, Bacterial - immunology | Shock, Septic - immunology | Shock, Septic - metabolism | Enterotoxins - immunology | T-Lymphocytes - metabolism | Histocompatibility Antigens Class II - metabolism | Receptors, Antigen, T-Cell - immunology | Staphylococcal Infections - microbiology | Staphylococcus aureus - metabolism | Protein Structure, Tertiary | Streptococcal Infections - microbiology | Receptors, Antigen, T-Cell - metabolism | Staphylococcal Infections - immunology | Streptococcal Infections - therapy | Gene Expression Regulation - immunology | Streptococcus pyogenes - immunology | Streptococcus pyogenes - metabolism | Superantigens - immunology | Protein Binding - immunology | Staphylococcal Infections - therapy | Sequence Alignment | Histocompatibility Antigens Class II - immunology | Superantigens - chemistry | Superantigens - genetics | Enterotoxins - metabolism | Staphylococcus aureus - immunology | T-Lymphocytes - immunology | Streptococcal Infections - immunology | Antigens, Bacterial - metabolism | Index Medicus
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3. Costimulation-mediated Rescue of Superantigen-activated T cells in an Animal Model of Kawasaki Disease
by Liang, Lisa
06/2012
Lactobacillus casei cell wall extract (LCWE)- induced coronary arteritis in mice models Kawasaki disease (KD). LCWE injections consist of T-cell dependent... 
0982 | superantigens | kawasaki disease
Dissertation
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4. Full Text Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction
by Revital Levy and Ziv Rotfogel and Dalia Hillman and Andrey Popugailo and Gila Arad and Emmanuelle Supper and Farhat Osman and Raymond Kaempfer
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 42, pp. E6437 - E6446
Full T-cell activation requires interaction between the costimulatory receptors B7-2 and CD28. By binding CD28, bacterial superantigens elicit harmful... 
Superantigen | Costimulatory receptor | B7-2 dimer interface | Cytokine storm | COMPLEX | B7-2 | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | superantigen | STAPHYLOCOCCAL ENTEROTOXIN-B | costimulatory receptor | STREPTOCOCCUS-PYOGENES | BETA-CHAIN | cytokine storm | LETHAL SHOCK | T-CELL-RECEPTOR | BINDING | CLASS-II | B7-2 Antigen - chemistry | B7-2 Antigen - genetics | Humans | Protein Multimerization | Recombinant Fusion Proteins | Superantigens - metabolism | CD28 Antigens - metabolism | Molecular Mimicry | Peptides - metabolism | Enterotoxins - immunology | Inflammation Mediators - metabolism | Female | Protein Interaction Domains and Motifs | Cytokines - genetics | Amino Acid Sequence | Protein Conformation, alpha-Helical | Cytokines - metabolism | Peptides - chemistry | Signal Transduction | Peptides - immunology | Models, Molecular | Superantigens - immunology | Protein Binding - immunology | B7-2 Antigen - metabolism | Animals | Superantigens - chemistry | Cell Line, Tumor | Mice | Enterotoxins - chemistry | Cytokines | Physiological aspects | Superantigens | Biological Sciences | PNAS Plus
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5. Dissecting The Role Of TNFα In Kawasaki Disease: Alteration Of Cell Fate By TNFα After Superantigen Activation
by Wong, Aaron
11/2011
Kawasaki disease (KD) is an acute inflammatory disease characterized by persistent inflammation of the coronary arteries. KD is characterized by the release of... 
0379 | 0982 | Superantigen | apoptosis | Kawasaki Disease | TNF
Dissertation
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6. The Role of 4-1BB in Kawasaki Disease
by Almeida, Fiona M
11/2011
Kawasaki disease (KD) is a multisystem vasculitis with predilection for the coronary arteries. Although the cause of KD remains elusive, there is evidence to... 
T-cell | costimulation | 0982 | Kawasaki Disease | superantigen
Dissertation
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7. Superantigens : molecular basis for their role in human disease
by Fraser, John D and Kotb, Malak
ISBN 1555814247, xii, 263
Bacteria | Immunology | Virulence factors | Superantigens
Book
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8. Human B-cell superantigens
by Zouali, Moncef, 1952
1996, Molecular biology intelligence unit (Unnumbered), ISBN 157059385X, 270
B-Lymphocytes | Superantigens | B cells
Book
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9. Efficacy and safety of combination ointment "fluticasone propionate 0.005% plus mupirocin 2.0%" for the treatment of atopic dermatitis with clinical suspicion of secondary bacterial infection: an open label uncontrolled study
by Khobragade, Kunal J
Efficacy and safety of combination ointment "fluticasone propionate 0.005% plus mupirocin 2.0%" for the treatment of atopic dermatitis with clinical suspicion of secondary bacterial infection: an open label uncontrolled study, 12/2005
BACKGROUND: The skin of patients with atopic dermatitis is colonized with Staphylococcus aureus. Reduction of bacterial colonization has been reported to be... 
Superantigens, Staphylococcus aureus, Topical corticosteroid, Topical antibiotic
Journal
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10. Bacterial superantigens
: structure, function, and therapeutic potential
by Sékaly, Rafick-Pierre and Thibodeau, Jacques
1995, Molecular biology intelligence unit (Unnumbered), ISBN 1570592640, 241
physiology | Bacterial antigens | Antigens, Bacterial | immunology | Superantigens | Staphylococcus aureus
Book
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11. Full Text Evolutionary paths of streptococcal and staphylococcal superantigens
by Okumura, Kayo and Shimomura, Yumi and Murayama, Somay Y and Yagi, Junji and Ubukata, Kimiko and Kirikae, Teruo and Miyoshi-Akiyama, Tohru
BMC Genomics, ISSN 1471-2164, 08/2012, Volume 13, Issue 1, pp. 404 - 404
Background: Streptococcus pyogenes (GAS) harbors several superantigens (SAgs) in the prophage region of its genome, although speG and smez are not located in... 
Superantigen | Bayes MCMC | Fenome comparison | Streptococcus | Staphylococcus | DYSGALACTIAE SUBSP EQUISIMILIS | BACTERIAL SUPERANTIGEN | PYROGENIC EXOTOXIN-G | PATHOGENICITY ISLAND | VIRULENCE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENES | GENETICS & HEREDITY | PYOGENES | TOXIC-SHOCK-SYNDROME | GROUP-A | GROUP-C | Staphylococcus aureus - genetics | Genome, Bacterial | Genome-Wide Association Study | Superantigens - classification | Humans | Selection, Genetic | Synteny | Molecular Sequence Data | Phylogeny | Sequence Analysis, DNA | Streptococcus pyogenes - genetics | Streptococcus - genetics | Base Sequence | Superantigens - genetics | Exotoxins - genetics | Bacterial Toxins - genetics | Monte Carlo Method | Amino Acid Substitution | Evolution, Molecular | Superantigens | Evolutionary genetics | Research | Properties | Natural history | Monte Carlo method | Genes | Genomics | Genetic research | Markov processes | Genomes | Comparative analysis | Proteins | Gram-positive bacteria | Bacteria
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12. The Role of Costimulation in the Persistence of the Immune Response in Kawasaki Disease
by Moolani, Yasmin
11/2009
Superantigens (SAgs) are implicated in the initiation of many diseases, including Kawasaki disease (KD), a multi-system vasculitis that leads to persistent... 
Immunology | Costimulation | 0982 | Superantigen | Kawasaki Disease
Dissertation
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13. Full Text Gram‐positive bacterial superantigen outside‐in signaling causes toxic shock syndrome
by Brosnahan, Amanda J and Schlievert, Patrick M
The FEBS Journal, ISSN 1742-464X, 12/2011, Volume 278, Issue 23, pp. 4649 - 4667
Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐positive pathogens capable of producing a variety of bacterial exotoxins known... 
Streptococcus pyogenes | toxic shock syndrome | superantigen | Staphylococcus aureus | MRSA | mucosal immunity | CLASS-II BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | LETHAL ENDOTOXIN-SHOCK | NECROSIS-FACTOR-ALPHA | MAJOR HISTOCOMPATIBILITY COMPLEX | NASAL EPITHELIAL-CELLS | STAPHYLOCOCCAL-ENTEROTOXIN-B | T-CELL-RECEPTOR | GROUP-A | STREPTOCOCCAL-PYROGENIC-EXOTOXIN | MHC CLASS-II | Antigen-Presenting Cells - metabolism | Epithelial Cells - metabolism | Signal Transduction | Humans | Virulence Factors - immunology | Shock, Septic - immunology | Superantigens - immunology | Antigen-Presenting Cells - immunology | Shock, Septic - metabolism | Superantigens - metabolism | Shock, Septic - microbiology | Gram-Positive Bacteria - metabolism | Animals | Superantigens - chemistry | Protein Conformation | Virulence Factors - metabolism | Gram-Positive Bacteria - immunology | T cells | Staphylococcus aureus infections | Toxic shock syndrome | Index Medicus
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14. Superantigen protocols
by Krakauer, Teresa and SpringerLink (Online service)
2003, Methods in molecular biology, ISBN 0896039846, Volume 214., xii, 259
Superantigens, a class of proteins produced by bacteria and microbes, cause diseases ranging from food poisoning to toxic shock, but can also be used to... 
Superantigens | Laboratory manuals | Antigens | Immunology | Biomedicine
Book
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15. Full Text Invariant Natural Killer T Cells Are Pathogenic in the HLA-DR4–Transgenic Humanized Mouse Model of Toxic Shock Syndrome and Can Be Targeted to Reduce Morbidity
by Szabo, Peter A and Rudak, Patrick T and Choi, Joshua and Xu, Stacey X and Schaub, Robert and Singh, Bhagirath and McCormick, John K and Haeryfar, S. M. Mansour
The Journal of Infectious Diseases, ISSN 0022-1899, 03/2017, Volume 215, Issue 5, pp. 824 - 829
Abstract During toxic shock syndrome (TSS), bacterial superantigens trigger a polyclonal T -cell response leading to a potentially catastrophic “cytokine... 
Invariant natural killer T cells | Cytokines | Superantigen | Inflammation | Staphylococcal enterotoxin B | Staphylococcus aureus | Toxic shock syndrome | ENCEPHALOMYELITIS | INFECTIOUS DISEASES | BACTERIAL SUPERANTIGENS | MICROBIOLOGY | toxic shock syndrome | IMMUNOLOGY | superantigen | CD1D-INDEPENDENT ACTIVATION | inflammation | cytokines | MICE | staphylococcal enterotoxin B | Superantigens - blood | Humans | Mice, Inbred C57BL | Mice, Transgenic | Shock, Septic - prevention & control | Shock, Septic - immunology | Superantigens - immunology | HLA-DR4 Antigen - genetics | Animals | Enterotoxins - immunology | Mice | Disease Models, Animal | Natural Killer T-Cells - immunology
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16. Full Text Identification and characterization of a novel staphylococcal emetic toxin
by Ono, Hisaya K and Sato'o, Yusuke and Narita, Kouji and Naito, Ikunori and Hirose, Shouhei and Hisatsune, Junzo and Asano, Krisana and Hu, Dong-Liang and Omoe, Katsuhiko and Sugai, Motoyuki and Nakane, Akio
Applied and Environmental Microbiology, ISSN 0099-2240, 2015, Volume 81, Issue 20, pp. 7034 - 7040
Staphylococcal enterotoxins (SEs) produced by Staphylococcus aureus have superantigenic and emetic activities, which cause toxic shock syndrome and... 
RESISTANT | PROTEIN | SUPERANTIGENS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SHOCK-SYNDROME | MICROBIOLOGY | ENTEROTOXIN GENE | AUREUS | INFECTION | CLUSTER | GENOME | Foodborne Diseases - microbiology | Enterotoxins - toxicity | Humans | Molecular Sequence Data | RNA, Messenger - analysis | Enterotoxins - isolation & purification | Gene Expression Profiling | Superantigens - isolation & purification | Recombinant Proteins - isolation & purification | Emetics - pharmacology | Cattle | Shrews | Leukocytes, Mononuclear - immunology | Staphylococcus aureus - metabolism | Staphylococcus aureus - genetics | Leukocytes, Mononuclear - drug effects | Staphylococcus aureus - isolation & purification | Cytokines - secretion | Recombinant Proteins - genetics | Superantigens - immunology | Sequence Analysis, DNA | Sequence Homology, Amino Acid | Mastitis, Bovine - microbiology | Enterotoxins - genetics | Nasal Mucosa - microbiology | Animals | Superantigens - genetics | Recombinant Proteins - toxicity | Cell Proliferation - drug effects | Physiological aspects | Microbial toxins | Genetic aspects | Research | Staphylococcus | Index Medicus | Food Microbiology
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17. Superantigens
: molecular basis for their role in human diseases
by Kotb, Malak and Fraser, John D and American Society for Microbiology
2007, ISBN 1555814247, xii, 263
physiology | Bacteria | Virulence Factors | immunology | Superantigens
Book
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18. Full Text The Retrovirus/Superantigen Hypothesis of Multiple Sclerosis
by Emmer, Alexander and Staege, Martin S and Kornhuber, Malte E
Cellular and Molecular Neurobiology, ISSN 0272-4340, 11/2014, Volume 34, Issue 8, pp. 1087 - 1096
The pathogenesis of multiple sclerosis (MS) is as yet unknown. Commonly, MS is assumed to be due to an autoimmune inflammation of the central nervous system... 
Therapy | Neurosciences | Multiple sclerosis | Biomedicine | Pathogenesis | Human endogenous retrovirus (HERV) | Neurobiology | Envelope protein | Superantigen | Cell Biology | ENDOGENOUS RETROVIRUS-K | SUPERANTIGEN STAPHYLOCOCCAL-ENTEROTOXIN | NEUROSCIENCES | IMMEDIATE-EARLY PROTEINS | CELL BIOLOGY | CYTOTOXIC T-CELLS | HERPES-SIMPLEX-VIRUS | TOXIC SHOCK SYNDROME | LONG TERMINAL REPEAT | HERV-K18 SUPERANTIGEN | ANTIGEN SELF-PRESENTATION | EPSTEIN-BARR-VIRUS | Animals | Humans | Immunotherapy | Multiple Sclerosis - immunology | Endogenous Retroviruses - immunology | Superantigens - immunology | Antigen Presentation - immunology | Multiple Sclerosis - therapy | Disease Progression | Proteins | Development and progression | T cells
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