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2009, ISBN 9789812833792, xxx, 691
Book
Journal Article
Science, ISSN 0036-8075, 1/2010, Volume 327, Issue 5961, pp. 94 - 97
Noncoding RNA is emerging as an important regulator of gene expression in many organisms. We are characterizing RNA-mediated chromatin silencing of the... 
Chromatin | RNA | Genes | Polyadenylation | Histones | Antisense RNA | Reports | Gene expression regulation | Repression | Transgenes | Genetic mutation | RNA-POLYMERASE-II | FLOWERING-TIME | PROTEIN | AUTONOMOUS PATHWAY | FCA | MULTIDISCIPLINARY SCIENCES | HETEROCHROMATIN | REQUIRES | REGULATORS | TERMINATION | REVEALS | Chromatin - metabolism | RNA-Binding Proteins - genetics | Arabidopsis - growth & development | mRNA Cleavage and Polyadenylation Factors - metabolism | Cleavage Stimulation Factor - metabolism | RNA, Plant - metabolism | Cleavage Stimulation Factor - genetics | Arabidopsis Proteins - metabolism | Gene Expression Regulation, Plant | Transcription, Genetic | mRNA Cleavage and Polyadenylation Factors - genetics | Arabidopsis Proteins - genetics | Histone Deacetylases - genetics | RNA Processing, Post-Transcriptional | MADS Domain Proteins - genetics | Gene Silencing | Histone Deacetylases - metabolism | Flowers - growth & development | Arabidopsis - metabolism | Arabidopsis - genetics | MADS Domain Proteins - metabolism | Epistasis, Genetic | RNA, Antisense - metabolism | Models, Genetic | Chromatin - genetics | RNA-Binding Proteins - metabolism | Suppression, Genetic | Arabidopsis thaliana | Gene silencing | Genetic aspects | Research | Genetic transcription | Properties | Flowering locus C | Plant biology | Flowers & plants | Ribonucleic acid--RNA | Gene expression | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 217 - 228
Loss of the tumor suppressor gene von Hippel-Lindau (VHL) plays a key role in the oncogenesis of clear cell renal cell carcinoma (CCRCC). The loss leads to... 
MEDICINE, RESEARCH & EXPERIMENTAL | HIF-1 | TUMOR SUPPRESSION | CYCLIN D1 | PATHWAY | GENE ALTERATIONS | VHL | KIDNEY | FATE | EXPRESSION | CANCER | Neoplasm Transplantation | RNA, Small Interfering - genetics | Humans | Carcinoma, Renal Cell - genetics | Male | Intracellular Signaling Peptides and Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Transformation, Neoplastic - genetics | Serrate-Jagged Proteins | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Membrane Proteins - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Carcinoma, Renal Cell - drug therapy | Intracellular Signaling Peptides and Proteins - genetics | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Carcinoma, Renal Cell - pathology | Membrane Proteins - genetics | RNA, Small Interfering - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Signal Transduction - genetics | Receptor, Notch1 - metabolism | Cell Transformation, Neoplastic - metabolism | Cyclin-Dependent Kinase Inhibitor p27 | Carcinoma, Renal Cell - metabolism | Animals | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | Mice | Cell Transformation, Neoplastic - drug effects | Receptor, Notch1 - antagonists & inhibitors | Cell Transformation, Neoplastic - pathology | Receptor, Notch1 - genetics | Calcium-Binding Proteins - genetics | Care and treatment | Enzyme inhibitors | Tumor suppressor genes | Dosage and administration | Genetic aspects | Carcinoma, Renal cell | Research | Health aspects | Index Medicus | Abridged Index Medicus | RNA; Small Interfering/genetics/pharmacology | Membrane Proteins/genetics/metabolism | Mice; Nude | Signal Transduction/drug effects/genetics | Intracellular Signaling Peptides and Proteins/genetics/metabolism | Basic Helix-Loop-Helix Transcription Factors/genetics/metabolism | Receptor; Notch1/antagonists & inhibitors/genetics/metabolism | Von Hippel-Lindau Tumor Suppressor Protein/genetics/metabolism | Cell Transformation; Neoplastic/drug effects/genetics/metabolism/pathology | Cyclin-Dependent Kinase Inhibitor p21/genetics/metabolism | Cell Line; Tumor | Intercellular Signaling Peptides and Proteins/genetics/metabolism | Calcium-Binding Proteins/genetics/metabolism | Carcinoma; Renal Cell/drug therapy/genetics/metabolism/pathology
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 4, pp. 593 - 605
The yeast histone deacetylase Rpd3 can be recruited to promoters to repress transcription initiation. Biochemical, genetic, and gene-expression analyses show... 
RNA-POLYMERASE-II | CHROMATIN REMODELING COMPLEX | TRANSCRIPTION ELONGATION-FACTORS | REGULATES H3 METHYLATION | TARGETED RECRUITMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENE-EXPRESSION | DEACETYLASE COMPLEX | SACCHAROMYCES-CEREVISIAE | H2A VARIANT HTZ1 | CELL BIOLOGY | Acetyltransferases - metabolism | Oligonucleotide Array Sequence Analysis | Saccharomyces cerevisiae - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Molecular Sequence Data | RNA Polymerase II - metabolism | Acetyltransferases - genetics | Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae - metabolism | Sirtuin 2 | Gene Deletion | Lysine - metabolism | Acetylation | Cyclin-Dependent Kinases - genetics | Sirtuins - genetics | Repressor Proteins - metabolism | Gene Expression Regulation, Fungal | Amino Acid Sequence | Histone Deacetylases - genetics | Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | Mutation - genetics | Down-Regulation - genetics | Sequence Homology, Amino Acid | Transcription Factors - metabolism | Epistasis, Genetic | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Histones - metabolism | Methylation | Sirtuins - metabolism | Cluster Analysis | Suppression, Genetic | Medical colleges | Methyltransferases | RNA | Lysine | Medical genetics | Histones | Nucleosomes | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e45277 - e45277
Cassava brown streak disease (CBSD) and cassava mosaic disease (CMD) are currently two major viral diseases that severely reduce cassava production in large... 
TRANSFORMATION | NICOTIANA-BENTHAMIANA | MIXED INFECTIONS | SMALL RNAS | PLANT-VIRUSES | MULTIDISCIPLINARY SCIENCES | DISEASE | DNA-A | EAST-AFRICA | SUPPRESSION | TRANSGENIC CASSAVA | Inverted Repeat Sequences - genetics | Transformation, Genetic | RNA, Small Interfering - genetics | Plant Immunity - genetics | Viral Proteins - chemistry | Plant Diseases - immunology | Manihot - genetics | Africa South of the Sahara | Viral Proteins - genetics | Manihot - virology | Sequence Analysis, DNA | Begomovirus - physiology | Genetic Engineering | Plant Diseases - virology | Potyviridae - physiology | RNA, Viral - genetics | Plants, Genetically Modified | Potyviridae - pathogenicity | Begomovirus - pathogenicity | Agrobacterium - genetics | Plant Diseases - genetics | Manihot - immunology | RNA, Small Interfering - metabolism | Usage | Diseases and pests | Plant immunology | Genetic aspects | Genetic engineering | Research | Cassava | Biotechnology | Transformation | Genes | Viral diseases | Transgenic | Viruses | Biology | Infections | Immunity | Proteins | Mosaic disease | Disease resistance | Inoculation | Conserved sequence | Load resistance | Coat protein | Plant viruses | Species | Deoxyribonucleic acid--DNA | Cultivars | Streak | Plant diseases | Regeneration | MicroRNAs | Binding sites | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
New Phytologist, ISSN 0028-646X, 2/2012, Volume 193, Issue 3, pp. 570 - 575
Journal Article