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Nature Cell Biology, ISSN 1465-7392, 2015, Volume 17, Issue 8, pp. 1074 - 1087
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-genome siRNA-based reverse genetics... 
JOUBERT-SYNDROME | RPGRIP1 | TRANSPORT | CENTRIOLE BIOGENESIS | PROTEIN | C-ELEGANS | MUTATIONS | PHOTORECEPTOR CELLS | MASTER REGULATOR | PRIMARY CILIA | CELL BIOLOGY | Humans | Pregnancy Proteins - genetics | Databases, Genetic | Suppressor Factors, Immunologic - genetics | Photoreceptor Cells - ultrastructure | Pregnancy Proteins - metabolism | Ellis-Van Creveld Syndrome - genetics | Cerebellum - abnormalities | Genetic Testing - methods | Suppressor Factors, Immunologic - metabolism | Membrane Proteins - deficiency | Transfection | RNA Interference | HEK293 Cells | Kidney Diseases, Cystic - genetics | Genomics - methods | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Caenorhabditis elegans - metabolism | Cilia - pathology | Caenorhabditis elegans - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Abnormalities, Multiple | Genetic Markers | Eye Abnormalities - genetics | Cilia - metabolism | Zebrafish - genetics | Cilia - genetics | Mice, Knockout | Proteins - genetics | Caenorhabditis elegans - ultrastructure | Phenotype | Animals | Cerebellar Diseases - genetics | Ciliary Motility Disorders - pathology | Proteins - metabolism | Photoreceptor Cells - metabolism | Zebrafish - metabolism | Retina - abnormalities | High-Throughput Nucleotide Sequencing | Ciliary Motility Disorders - metabolism | Mutation | Ciliary Motility Disorders - genetics | RNA | Cilia and ciliary motion | Genetic research | Biosynthesis | Genetic aspects | Research | Gene expression | Properties | reverse genetics | cilia | ciliopathies | Joubert syndrome | whole-genome siRNA screen | Jeune syndrome
Journal Article
Journal Article
Analytical Chemistry, ISSN 0003-2700, 12/2018, Volume 90, Issue 24, pp. 14287 - 14293
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 12/2013, Volume 70, Issue 23, pp. 4617 - 4630
Invasiveness is a common feature of trophoblast and tumors; however, while tumor invasion is uncontrolled, trophoblast invasion is strictly regulated. Both... 
Life Sciences | Biochemistry, general | Life Sciences, general | PIBF | Tumor | Zebrafish | Trophoblast | Biomedicine general | Invasion | Cell Biology | CELLS | SIGNALING PATHWAYS | EGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | STAT3 ACTIVATION | FACTOR PIBF | SIGNAL-TRANSDUCER-AND-ACTIVATOR-OF-TRANSCRIPTION-3 | CANCER DEVELOPMENT | GROWTH-FACTORS | GENE-EXPRESSION | BINDING | Neoplasms - metabolism | Embryo, Nonmammalian - cytology | Humans | Pregnancy Proteins - genetics | Embryo, Nonmammalian - metabolism | Suppressor Factors, Immunologic - genetics | Transplantation, Heterologous | Green Fluorescent Proteins - genetics | Pregnancy Proteins - metabolism | Zebrafish - embryology | Promoter Regions, Genetic - genetics | Suppressor Factors, Immunologic - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Trophoblasts - transplantation | Matrix Metalloproteinase 9 - metabolism | Neoplasms - genetics | RNA Interference | Matrix Metalloproteinase 9 - genetics | Trophoblasts - cytology | Cell Line | Green Fluorescent Proteins - metabolism | Trophoblasts - metabolism | Animals, Genetically Modified | Matrix Metalloproteinase 2 - metabolism | HCT116 Cells | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Signal Transduction - genetics | Blotting, Western | Zebrafish - genetics | Heparin-binding EGF-like Growth Factor | Matrix Metalloproteinase 2 - genetics | Microscopy, Confocal | Animals | Zebrafish - metabolism | Cell Line, Tumor | Protein Binding | Neoplasms - pathology | Cell Movement | Cell Transplantation - methods | Progesterone | Tumors | Signal transduction | Proteases | Cell adhesion & migration | Cancer
Journal Article
Journal Article