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1. Full Text Suprachiasmatic nucleus: Cell autonomy and network properties
by Welsh, David K and Takahashi, Joseph S and Kay, Steve A
Annual Review of Physiology, ISSN 0066-4278, 03/2009, Volume 72, Issue 1, pp. 551 - 577
The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals. Individual SCN neurons in dispersed culture can generate independent circadian... 
Circadian | Clock | Coupling | PHYSIOLOGY | SELF-SUSTAINED OSCILLATORS | clock | MAMMALIAN CIRCADIAN CLOCK | PERIPHERAL-TISSUES | coupling | circadian | IN-VITRO | VPAC RECEPTOR | INDUCED PHASE-SHIFTS | VASOACTIVE INTESTINAL POLYPEPTIDE | GENE-EXPRESSION | RHYTHM GENERATION | BIOLOGICAL CLOCK | Drosophila | Humans | Circadian Rhythm - physiology | Photoperiod | Suprachiasmatic Nucleus - anatomy & histology | Nerve Net - physiology | Nerve Net - cytology | Suprachiasmatic Nucleus - physiology | Animals | Biological Clocks - physiology | Nerve Net - anatomy & histology | Light | Neurons - physiology | Hormones - physiology | Suprachiasmatic Nucleus - chemistry | Circadian rhythms | Neurons | Analysis | Physiological aspects | Genetic aspects | Gene expression | Mammals
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2. Full Text Central and peripheral circadian clocks in mammals
by Mohawk, Jennifer A and Green, Carla B and Takahashi, Joseph S
Annual Review of Neuroscience, ISSN 0147-006X, 07/2012, Volume 35, Issue 1, pp. 445 - 462
The circadian system of mammals is composed of a hierarchy of oscillators that function at the cellular, tissue, and systems levels. A common molecular... 
temperature | clock genes | metabolism | suprachiasmatic nucleus | oscillator coupling | DORSOMEDIAL HYPOTHALAMIC NUCLEUS | FOOD-ANTICIPATORY ACTIVITY | NEUROSCIENCES | INDIVIDUAL FIBROBLASTS | RETINAL GANGLION-CELLS | GLUCOSE-HOMEOSTASIS | REVEALS PERSISTENT | PARAVENTRICULAR NUCLEUS | GENE-EXPRESSION | ENERGY-METABOLISM | Methamphetamine - pharmacology | Suprachiasmatic Nucleus - drug effects | Circadian Clocks - drug effects | Circadian Rhythm - physiology | Neural Pathways - physiology | Feeding Behavior - physiology | Suprachiasmatic Nucleus - physiology | Animals | Models, Biological | Mammals - physiology | Neurons - physiology | Neural Pathways - metabolism | Signal Transduction - physiology | Suprachiasmatic Nucleus - metabolism | Neurons - metabolism | Circadian Clocks - physiology | Circadian Rhythm - drug effects | Circadian rhythms | Physiological aspects | Genetic aspects | Research | Genes | Clock Genes | Suprachiasmatic Nucleus | Temperature | Metabolism | Oscillator Coupling
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3. Full Text Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling
by Brancaccio, Marco and Patton, Andrew P and Chesham, Johanna E and Maywood, Elizabeth S and Hastings, Michael H
Neuron, ISSN 0896-6273, 03/2017, Volume 93, Issue 6, pp. 1420 - 1435.e5
The suprachiasmatic nucleus (SCN) of the hypothalamus orchestrates daily rhythms of physiology and behavior in mammals. Its circadian (∼24 hr) oscillations of... 
circadian | circuit synchronization | membrane potential oscillations | astrocytic-neuronal interactions | GABA | circadian behavior | extracellular glutamate | calcium oscillations | SCN | NMDAR2C | MOUSE | GLUTAMINE-SYNTHETASE | NEURONS | INHIBITORY SYNAPTIC-TRANSMISSION | RECEPTOR-CHANNEL | NEURAL CIRCUITS | DIVERSITY | CLOCK | EXPRESSION | NEUROSCIENCES | NONCOMPETITIVE INHIBITION | Motor Activity - physiology | Glutamic Acid - physiology | Male | Mice, Transgenic | Circadian Rhythm - physiology | Receptors, N-Methyl-D-Aspartate - physiology | Receptors, N-Methyl-D-Aspartate - genetics | Suprachiasmatic Nucleus - physiology | Astrocytes - physiology | Animals | Neurons - physiology | Female | Mice | Circadian Clocks - physiology | Glutamate | Gene expression | Neurons | Neurophysiology | Molecular biology | Circadian rhythms | Suprachiasmatic nucleus | Cell culture | Daytime | Circadian rhythm | Hypothalamus | Metabolism | Nuclei | Clocks
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4. Full Text Circadian Pacemaking in Cells and Circuits of the Suprachiasmatic Nucleus
by Hastings, M. H and Brancaccio, M and Maywood, E. S
Journal of Neuroendocrinology, ISSN 0953-8194, 01/2014, Volume 26, Issue 1, pp. 2 - 10
The suprachiasmatic nucleus (SCN) of the hypothalamus is the principal circadian pacemaker of the brain. It co‐ordinates the daily rhythms of sleep and... 
sleep | VIP | paracrine | DREADD | pharmacogenetic | Paracrine | Pharmacogenetic | Sleep | SLEEP DURATION | BEHAVIOR | MOUSE | LIGHT | OSCILLATOR | NEUROSCIENCES | OBESITY | RHYTHMS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | REV-ERB-ALPHA | CLOCK | Period Circadian Proteins - physiology | Animals | Vasoactive Intestinal Peptide - physiology | Cryptochromes - physiology | Neurons - physiology | Suprachiasmatic Nucleus - cytology | Signal Transduction - physiology | Circadian Rhythm - physiology | Feedback, Physiological - physiology | Circadian Clocks - physiology | Neural Pathways - physiology | Suprachiasmatic Nucleus - physiology | Proteins | Physiological aspects | Pharmacogenetics | Vasoactive intestinal peptides | Brain | Review
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5. Full Text Generation of circadian rhythms in the suprachiasmatic nucleus
by Hastings, Michael H and Maywood, Elizabeth S and Brancaccio, Marco
Nature Reviews Neuroscience, ISSN 1471-003X, 08/2018, Volume 19, Issue 8, pp. 453 - 469
The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering only about 10,000 neurons on each side of the third ventricle, the SCN... 
SLEEP | GABA TRANSPORTERS | BEHAVIOR | MOUSE | PERIOD | CALCIUM RHYTHM | NEURONS | OSCILLATIONS | CASEIN KINASE 1 | NEUROSCIENCES | CELLULAR CLOCKS | Astrocytes - physiology | Animals | Signal Transduction | Humans | Neurons - physiology | Circadian Clocks | Circadian Rhythm | Suprachiasmatic Nucleus - physiology | Suprachiasmatic nucleus | Circadian rhythms | Genetic transcription | Research | Health aspects | Cell culture | Transcription | Astrocytes | Circuits | Ventricles (cerebral) | Nervous system | Hypothalamus | Circadian rhythm | Post-translation | Ventricle | Biological clocks
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6. Full Text The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms
by Saper, Clifford B and Gooley, Joshua J and Schomer, Ashley
Nature Neuroscience, ISSN 1097-6256, 03/2006, Volume 9, Issue 3, pp. 398 - 407
Circadian rhythms of behavior and physiology can be entrained by daily cycles of restricted food availability, but the pathways that mediate food entrainment... 
EFFERENT PROJECTIONS | ORGANIZATION | BODY-WEIGHT | TEMPERATURE RHYTHMICITY | RAT | SUPRACHIASMATIC NUCLEUS | VENTROLATERAL PREOPTIC NUCLEUS | ANTICIPATORY ACTIVITY | FEEDING SCHEDULES | NEUROSCIENCES | LESIONS | Motor Activity - physiology | Conditioning (Psychology) - physiology | Dorsomedial Hypothalamic Nucleus - physiology | Proto-Oncogene Proteins c-fos - metabolism | Rats | Dorsomedial Hypothalamic Nucleus - anatomy & histology | Male | Circadian Rhythm - physiology | Body Temperature - physiology | Neural Pathways - physiology | Food Deprivation - physiology | Neural Pathways - anatomy & histology | Animals | Biological Clocks - physiology | Time Factors | Wakefulness - physiology | Neurons - metabolism | Appetite Regulation - physiology | Denervation | Circadian rhythms | Biological research | Physiological aspects | Research | Hypothalamus | Biology, Experimental
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7. Full Text Physiology of circadian entrainment
by Golombek, Diego A and Rosenstein, Ruth E
Physiological Reviews, ISSN 0031-9333, 07/2010, Volume 90, Issue 3, pp. 1063 - 1102
Golombek DA, Rosenstein RE. Physiology of Circadian Entrainment. Physiol Rev 90: 1063-1102, 2010; doi:10.1152/physrev.00009.2009.-Mammalian circadian rhythms... 
CLOCK GENE-EXPRESSION | RETINAL GANGLION-CELLS | PHYSIOLOGY | INDUCED PHASE-SHIFTS | NITRIC-OXIDE SYNTHASE | FIBRILLARY ACIDIC PROTEIN | RAT SUPRACHIASMATIC NUCLEUS | CYCLASE-ACTIVATING PEPTIDE | CASEIN-KINASE-I | MESSENGER-RNA LEVELS | RHYTHM SLEEP DISORDERS | Retina - physiology | Retina - radiation effects | Animals | Biological Clocks - physiology | Gene Expression - physiology | Humans | Light | Neurons - physiology | Neurotransmitter Agents - metabolism | Signal Transduction - physiology | Circadian Rhythm - physiology | Suprachiasmatic Nucleus - physiology | Circadian rhythms | Physiological aspects | Photoreceptors | Retina | Research | Neurophysiology
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8. Full Text A hypothalamic circuit for the circadian control of aggression
by Todd, William D and Fenselau, Henning and Wang, Joshua L and Zhang, Rong and Machado, Natalia L and Venner, Anne and Broadhurst, Rebecca Y and Kaur, Satvinder and Lynagh, Timothy and Olson, David P and Lowell, Bradford B and Fuller, Patrick M and Saper, Clifford B
Nature Neuroscience, ISSN 1097-6256, 05/2018, Volume 21, Issue 5, pp. 717 - 724
'Sundowning' in dementia and Alzheimer's disease is characterized by early-evening agitation and aggression. While such periodicity suggests a circadian... 
EFFERENT PROJECTIONS | SLEEP | TRANSPORT | DEMENTIA | PARAVENTRICULAR NUCLEUS | SUPRACHIASMATIC NUCLEUS | OUTPUT | SUBPARAVENTRICULAR ZONE | NEUROSCIENCES | GABAERGIC NEURONS | BEHAVIORS | Aggression - physiology | Paraventricular Hypothalamic Nucleus - physiology | Hypothalamus - physiology | Mice, Inbred C57BL | Male | Circadian Rhythm - physiology | Optogenetics | Ventromedial Hypothalamic Nucleus - physiology | Neural Pathways - physiology | Suprachiasmatic Nucleus - physiology | gamma-Aminobutyric Acid - physiology | Excitatory Postsynaptic Potentials - physiology | Paraventricular Hypothalamic Nucleus - cytology | Animals | Hypothalamus - cytology | Vasoactive Intestinal Peptide - physiology | Neural Pathways - cytology | Brain Mapping | Mice | Ventromedial Hypothalamic Nucleus - cytology | Corticosterone - blood | Circadian rhythms | Control | Research | Hypothalamus | Aggressiveness (Psychology) | Suprachiasmatic nucleus | Aggressive behavior | Neurons | Aggression | Circuits | Periodicity | Circadian rhythm | Periodic variations | Disease control | Nuclei | Hypothalamus (ventromedial) | γ-Aminobutyric acid | Intestine | Vasoactive agents | Vasoactive intestinal peptide | Dementia disorders | Biological clocks
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9. Full Text Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators
by Mohawk, Jennifer A and Takahashi, Joseph S
Trends in Neurosciences, ISSN 0166-2236, 2011, Volume 34, Issue 7, pp. 349 - 358
The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of the master circadian pacemaker in mammals. The individual cells of the SCN are capable of... 
Neurology | PHASE-SHIFTS | CLOCK MUTATION | VPAC RECEPTOR | CONSTANT LIGHT | PROTEIN EXPRESSION | FUNCTIONAL-ANALYSIS | GASTRIN-RELEASING-PEPTIDE | AMBIENT-TEMPERATURE CYCLES | NEUROSCIENCES | NOCTURNAL RODENTS | FORCED DESYNCHRONIZATION | Animals | Humans | Neurons - physiology | Suprachiasmatic Nucleus - cytology | Neurons - cytology | Circadian Rhythm - physiology | Models, Neurological | Circadian Clocks - physiology | Nerve Net - physiology | Suprachiasmatic Nucleus - physiology
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