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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 1, pp. 218 - 224
Purpose A prognostic index for survival was constructed and validated from patient data from two European Organisation for Research and Treatment of Cancer... 
Radiology | Hematology, Oncology and Palliative Medicine | Radiotherapy | Prognostic factors | Low-grade glioma | SURVIVAL | CANCER EORTC | OLIGODENDROGLIOMA | EFFICACY | EUROPEAN ORGANIZATION | RANDOMIZED-TRIAL | CHEMOTHERAPY | RADIATION-THERAPY | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Prognosis | Prospective Studies | Astrocytoma - therapy | Humans | Middle Aged | Brain Neoplasms - pathology | Male | Glioma - radiotherapy | Glioma - genetics | Young Adult | Astrocytoma - pathology | Glioma - pathology | Mental Status Schedule | Adult | Female | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Astrocytoma - mortality | Astrocytoma - genetics | Glioma - psychology | Glioma - mortality | Brain Neoplasms - psychology | Supratentorial Neoplasms - pathology | Risk Factors | Brain Neoplasms - genetics | Supratentorial Neoplasms - mortality | Tumor Burden | Supratentorial Neoplasms - radiotherapy | Disease-Free Survival | Supratentorial Neoplasms - psychology | Analysis of Variance | Adolescent | Aged | Astrocytoma - psychology | Supratentorial Neoplasms - genetics | Care and treatment | Gliomas | Oncology, Experimental | Radiation | Research | Cancer | Index Medicus | GLIOMAS | SURGERY | NEOPLASMS | STATISTICS | ADULTS | VALIDATION | HISTOLOGY | MEDICINE | NUCLEAR MEDICINE | MATHEMATICS | MULTIVARIATE ANALYSIS | NERVOUS SYSTEM DISEASES | TESTING | DISEASES | THERAPY | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | AGE GROUPS | RADIOLOGY | HAZARDS
Journal Article
Brain Pathology, ISSN 1015-6305, 03/2018, Volume 28, Issue 2, pp. 172 - 182
Pleomorphic xanthoastrocytoma (PXA) is a rare localized glioma characterized by frequent BRAF V600E mutation and CDKN2A/B deletion. We explored the association... 
anaplastic pleomorphic xanthoastrocytoma | pleomorphic xanthoastrocytoma | glioma | BRAF | low‐grade glioma | low-grade glioma | GLIOMAS | ACTIVATION | PATHOLOGY | INDUCED SENESCENCE | NEUROSCIENCES | CLINICAL NEUROLOGY | FEATURES | DELETION | GLIOBLASTOMAS | PILOCYTIC ASTROCYTOMAS | DIFFUSE | ATYPICAL TERATOID/RHABDOID TUMOR | PROGRESSION | Follow-Up Studies | Humans | Middle Aged | Child, Preschool | Male | DNA Copy Number Variations | Glioma - genetics | Young Adult | SMARCB1 Protein - metabolism | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Glioma - pathology | Adult | Female | Cerebellar Neoplasms - pathology | Glioma - surgery | Child | Glioma - mortality | Supratentorial Neoplasms - pathology | Cerebellar Neoplasms - mortality | Neoplasm Recurrence, Local | Supratentorial Neoplasms - mortality | Cerebellar Neoplasms - genetics | Supratentorial Neoplasms - surgery | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Proto-Oncogene Proteins B-raf - genetics | Adolescent | Chromosome Aberrations | Mutation | Cerebellar Neoplasms - surgery | Supratentorial Neoplasms - genetics | Cytogenetics | Genetic aspects | Gene mutations | Gliomas | Chromosomes | Genomics | Transformation | Astrocytes | Copy number | Brain tumors | Cytology | Central nervous system diseases | Chromosome deletion | Hybridization | Gene deletion | Survival | Heterozygosity | Glioma | Clonal deletion | Chromosome 9 | Morphology | Loss of heterozygosity | Deletion | Tumors | Index Medicus
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 1/2017, Volume 133, Issue 1, pp. 5 - 12
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 12/2010, Volume 120, Issue 6, pp. 719 - 729
Journal Article
Neuro-Oncology, ISSN 1522-8517, 2/2011, Volume 13, Issue 2, pp. 212 - 222
Overall, pediatric high-grade glioma (pHGG) has a poor prognosis, in part due to the lack of understanding of the underlying biology. High-resolution 244 K... 
PDGFRA | CDKN2B | MYCN | Diffuse intrinsic pontine glioma | Genome wide analysis | Pediatric high-grade glioma | ADAM3A | COPY-NUMBER ABERRATIONS | genome wide analysis | DISTINCT | BRAIN-STEM GLIOMAS | TUMORS | diffuse intrinsic pontine glioma | CLINICAL NEUROLOGY | pediatric high-grade glioma | CHILDREN | GLIOBLASTOMAS | AMPLIFICATION | ONCOLOGY | MALIGNANT GLIOMAS | INTRACRANIAL EPENDYMOMA | CHROMOSOMAL IMBALANCES | Oncogene Proteins - genetics | Prognosis | Oligonucleotide Array Sequence Analysis | Brain Stem Neoplasms - pathology | Humans | Child, Preschool | Infant | Male | Loss of Heterozygosity | Brain Stem Neoplasms - metabolism | Chromosomes, Human, Pair 17 - genetics | Immunoenzyme Techniques | Glioma - metabolism | Glioma - genetics | Young Adult | Glioma - pathology | Polymerase Chain Reaction | Biomarkers, Tumor - metabolism | Adult | Female | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Child | Chromosome Deletion | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Supratentorial Neoplasms - pathology | Supratentorial Neoplasms - metabolism | Oncogene Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Survival Rate | Chromosome Mapping | Homozygote | ADAM Proteins - metabolism | Brain Stem Neoplasms - genetics | Gene Amplification | Comparative Genomic Hybridization | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adolescent | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Biomarkers, Tumor - genetics | DNA, Neoplasm - genetics | ADAM Proteins - genetics | Supratentorial Neoplasms - genetics | Chromosomes, Human, Pair 14 - genetics | Index Medicus | Basic and Translational Investigations
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 1/2016, Volume 131, Issue 1, pp. 137 - 146
Journal Article
Journal Article
Neurology, ISSN 0028-3878, 08/2012, Volume 79, Issue 9, pp. 883 - 889
Journal Article
World Neurosurgery, ISSN 1878-8750, 12/2018, Volume 120, pp. 442 - 447
Glioblastoma multiforme (GBM) is usually characterized by diffuse, infiltrative growth and local tumor progression. Extensive leptomeningeal metastases are... 
Biomarker | Outcome | Extracranial | Genetic profile | Salvage treatment | Glioblastoma multiforme | Leptomeningeal metastases | GLIOMAS | SURGERY | MICROSATELLITE INSTABILITY | ADULT | CLINICAL NEUROLOGY | DISSEMINATION | RADIOTHERAPY | EXPRESSION | Irinotecan - administration & dosage | Microsatellite Instability | Humans | Middle Aged | Male | Palliative Care | Glioblastoma - secondary | Chemoradiotherapy, Adjuvant | Temozolomide - therapeutic use | Neurosurgical Procedures | Glioblastoma - diagnostic imaging | Glioblastoma - genetics | Supratentorial Neoplasms - therapy | DNA Mutational Analysis | Supratentorial Neoplasms - diagnostic imaging | Antibodies, Monoclonal, Humanized - therapeutic use | Meningeal Neoplasms - genetics | Bevacizumab - administration & dosage | Supratentorial Neoplasms - pathology | Isocitrate Dehydrogenase - genetics | Radiotherapy | Sequence Analysis, DNA | Meningeal Neoplasms - therapy | Antineoplastic Agents, Alkylating - therapeutic use | Glioblastoma - therapy | Magnetic Resonance Imaging | Antineoplastic Agents, Immunological - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | High-Throughput Nucleotide Sequencing | Supratentorial Neoplasms - genetics | Meningeal Neoplasms - diagnostic imaging | Meningeal Neoplasms - secondary | Tyrosine | Chemotherapy | Development and progression | Palliative treatment | Metastasis | Methylation | Risk factors | Cancer | Index Medicus
Journal Article
Journal Article
Neuro-Oncology, ISSN 1522-8517, 8/2011, Volume 13, Issue 8, pp. 866 - 879
Central nervous system primitive neuroectodermal tumor (CNS PNET) and pineoblastoma are highly malignant embryonal brain tumors with poor prognoses. Current... 
CDKN2A/CDKN2B | CNS PNET | SNP array | Pineoblastoma | Copy number imbalance | NUMBER | copy number imbalance | HYBRIDIZATION DETECTS | SUPRATENTORIAL | CHILDHOOD | CLINICAL NEUROLOGY | CYTOGENETIC ANALYSIS | CHILDREN | PATHWAY ACTIVATION | ONCOLOGY | pineoblastoma | PEDIATRIC BRAIN-TUMORS | GENETIC-HETEROGENEITY | MEDULLOBLASTOMA | Neuroectodermal Tumors, Primitive - genetics | Oligonucleotide Array Sequence Analysis | Humans | Pineal Gland - metabolism | Pinealoma - metabolism | Child, Preschool | Infant | Male | Gene Expression Profiling | Brain Neoplasms - metabolism | Immunoenzyme Techniques | Pineal Gland - pathology | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Polymerase Chain Reaction | Biomarkers, Tumor - metabolism | Female | DNA, Neoplasm - analysis | Child | Neuroectodermal Tumors, Primitive - metabolism | Neoplasm Recurrence, Local - metabolism | Vesicular Transport Proteins - genetics | Brain Neoplasms - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Adolescent | Polymorphism, Single Nucleotide - genetics | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | DNA, Neoplasm - genetics | Genome, Human | Pinealoma - genetics | Calcium-Binding Proteins - genetics | Index Medicus | CDKN2B | CDKN2A | Basic and Translational Investigations
Journal Article