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The Journal of immunology (1950), ISSN 1550-6606, 2005, Volume 174, Issue 11, pp. 6943 - 6954
Lung surfactant protein A (SP-A) and D (SP-D) are innate immune molecules which are known to interact with allergens and immune cells and modulate cytokine and chemokine profiles during host hypersensitivity response... 
MACROPHAGE FUNCTION | A SP-A | II CELL HYPERTROPHY | TARGETED MICE | EOSINOPHIL RECRUITMENT | IMMUNE-RESPONSES | IN-VIVO | HISTAMINE-RELEASE | IMMUNOLOGY | NF-KAPPA-B | LYMPHOCYTE-PROLIFERATION | Recombinant Proteins - therapeutic use | Interleukin-13 - antagonists & inhibitors | Humans | Pulmonary Eosinophilia - genetics | Male | Pulmonary Surfactant-Associated Protein A - administration & dosage | Interleukin-5 - biosynthesis | Interleukin-15 - biosynthesis | Interleukin-13 - biosynthesis | Allergens - administration & dosage | Allergens - immunology | Female | Erythropoietin - metabolism | Erythropoietin - biosynthesis | Pulmonary Surfactant-Associated Protein A - genetics | Pulmonary Eosinophilia - immunology | Pulmonary Surfactant-Associated Protein D - deficiency | Genetic Predisposition to Disease - genetics | Pulmonary Eosinophilia - prevention & control | Serum Albumin, Bovine - immunology | Mice, Inbred C57BL | Cells, Cultured | Interleukin-15 - antagonists & inhibitors | Antigens, Fungal - immunology | Aspergillosis, Allergic Bronchopulmonary - genetics | Pulmonary Surfactant-Associated Protein D - administration & dosage | Aspergillosis, Allergic Bronchopulmonary - pathology | Pulmonary Surfactant-Associated Protein D - genetics | Recombinant Proteins - administration & dosage | Mice, Knockout | Animals | Antigens, Fungal - administration & dosage | Aspergillosis, Allergic Bronchopulmonary - immunology | Aspergillus fumigatus - immunology | Pulmonary Surfactant-Associated Protein D - therapeutic use | Mice | Pulmonary Surfactant-Associated Protein A - deficiency
Journal Article
Orphanet journal of rare diseases, ISSN 1750-1172, 2009, Volume 4, Issue 1, pp. 29 - 29
...); however, the effectiveness of GM-CSF in treating LPI associated PAP is uncertain. We hypothesized that GM-CSF and surfactant protein D (SP-D... 
MEDICINE, RESEARCH & EXPERIMENTAL | HOMEOSTASIS IN-VIVO | PULMONARY SURFACTANT | SLC7A7 GENE | COLONY-STIMULATING FACTOR | WHOLE-LUNG LAVAGE | DISEASE | GENETICS & HEREDITY | INNATE | GENE-TARGETED MICE | DEFICIENT MICE | TRANSGENIC MICE | Granuloma - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Amino Acid Metabolism, Inborn Errors - physiopathology | Humans | Child, Preschool | Pulmonary Alveoli - physiology | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Lung - cytology | Amino Acid Metabolism, Inborn Errors - metabolism | Pulmonary Alveoli - metabolism | Pulmonary Alveolar Proteinosis - metabolism | Adult | Bronchoalveolar Lavage Fluid - cytology | Lung - metabolism | Lysine - metabolism | Pulmonary Alveolar Proteinosis - therapy | Pulmonary Alveolar Proteinosis - physiopathology | Macrophages, Alveolar - physiology | Treatment Outcome | Pulmonary Surfactant-Associated Protein D - metabolism | Cholesterol - metabolism | Amino Acid Metabolism, Inborn Errors - immunology | Amino Acid Metabolism, Inborn Errors - therapy | Pulmonary Alveolar Proteinosis - immunology | Pulmonary Surfactant-Associated Protein D - therapeutic use | Bronchoalveolar Lavage Fluid - chemistry | Care and treatment | Surfactant protein D | Pulmonary alveolar proteinosis | Physiological aspects | Genetic aspects | Research | Granulocyte-macrophage colony stimulating factor | Proteins | Mutation | Lungs | Surfactants
Journal Article
Journal Article
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 10/2002, Volume 130, Issue 1, pp. 19 - 24
...). A comparison of the effect of treatment of allergen challenged mice by intranasal administration of a 60-kDa truncated recombinant form of human SP-D (rfhSP-D... 
ABPA allergy IL-12 plethysmography SP-D | ABPA allergy IL‐12 plethysmography SP‐D | ABPA allergy | SURFACTANT PROTEIN-A | INTERLEUKIN-12 | HISTAMINE-RELEASE | IMMUNOLOGY | BRONCHOPULMONARY ASPERGILLOSIS | SP-D | INTERFERON-GAMMA | IL-12 plethysmography | INFLAMMATION | ASTHMA | AIRWAY HYPERRESPONSIVENESS | CYSTIC-FIBROSIS | EXPRESSION | Pulmonary Surfactant-Associated Protein D - analysis | Antigens, Plant | Spleen - immunology | Antibodies, Fungal - biosynthesis | Recombinant Fusion Proteins - pharmacology | Humans | Fungal Proteins - toxicity | Pulmonary Surfactant-Associated Protein A - analysis | Aspergillosis, Allergic Bronchopulmonary - drug therapy | Allergens - immunology | Fungal Proteins - immunology | Eosinophilia - drug therapy | Allergens - toxicity | Antigens, Fungal - toxicity | Bronchial Hyperreactivity - chemically induced | Immunization | Pulmonary Surfactant-Associated Protein A - pharmacology | Plethysmography, Whole Body | Antigens, Fungal - immunology | Interleukin-4 - analysis | Aspergillosis, Allergic Bronchopulmonary - chemically induced | Pulmonary Surfactant-Associated Protein D - chemistry | Aspergillus fumigatus - immunology | Mice | Mice, Inbred BALB C | Peptide Fragments - therapeutic use | Pulmonary Surfactant-Associated Protein A - therapeutic use | Eosinophilia - chemically induced | Species Specificity | Bronchial Hyperreactivity - drug therapy | Recombinant Fusion Proteins - therapeutic use | Peptide Fragments - pharmacology | Pulmonary Surfactant-Associated Protein D - pharmacology | Female | Drug Evaluation, Preclinical | Spleen - pathology | Recombinant Fusion Proteins - administration & dosage | Interleukin-12 - analysis | Lung - pathology | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Pulmonary Surfactant-Associated Protein D - administration & dosage | Antibodies, Fungal - immunology | Administration, Intranasal | Aspergillosis, Allergic Bronchopulmonary - pathology | Spleen - chemistry | Interferon-gamma - analysis | Animals | Pulmonary Surfactant-Associated Protein D - therapeutic use | Animal Studies
Journal Article
Journal Article
Lung, ISSN 0341-2040, 2/2015, Volume 193, Issue 1, pp. 25 - 30
Surfactant protein D (SP-D) plays an important role in the innate responses against pathogens and its production is altered in lung... 
Biomarker | Pneumology/Respiratory System | Medicine & Public Health | A/H1N1 virus | Influenza | Mortality | Surfactant protein D (SP-D) | ARDS | ACUTE LUNG INJURY | PNEUMONIA | H1N1 | MEXICO | BIOMARKERS | RESPIRATORY SYSTEM | IDIOPATHIC PULMONARY-FIBROSIS | EXPRESSION | Multivariate Analysis | Up-Regulation | Prognosis | Humans | Middle Aged | Critical Illness | Male | Respiratory Distress Syndrome, Adult - mortality | Pneumonia, Viral - blood | Case-Control Studies | Respiratory Distress Syndrome, Adult - blood | Time Factors | Influenza, Human - mortality | Adult | Female | Influenza, Human - diagnosis | Influenza, Human - virology | Influenza, Human - therapy | Respiratory Distress Syndrome, Adult - therapy | Hospital Mortality | Pneumonia, Viral - therapy | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Pulmonary Surfactant-Associated Protein D - blood | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - blood | Logistic Models | Biomarkers - blood | Chi-Square Distribution | Respiratory Distress Syndrome, Adult - diagnosis | Respiratory Distress Syndrome, Adult - virology | Pneumonia, Viral - diagnosis | Pneumonia, Viral - mortality | Pneumonia, Viral - virology | Acute respiratory distress syndrome | Influenza viruses | Immune response | Causes of | Physiological aspects | Development and progression | Genetic aspects | Research | Membrane proteins | H1N1 virus
Journal Article
Disease Markers, ISSN 0278-0240, 2012, Volume 33, Issue 2, pp. 91 - 100
Introduction : There are limited data linking serum levels of surfactant protein D, its genetic polymorphisms to the risk of Chronic Obstructive Pulmonary Disease (COPD). Objectives... 
SP-D SNPs | Surfactant protein D | COPD risk | serum SP-D levels | SP-D haplotypes | Other
Journal Article
FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 07/2019, Volume 9, p. 565
Surfactant Protein D (SP-D), a pattern recognition innate immune molecule, has been implicated in the immune surveillance against cancer A recent report showed an association of decreased SP-D expression in human prostate... 
LOCALIZATION | SURFACTANT PROTEIN-D | PHOSPHORYLATION | apoptosis | pAkt | prostate tumor explants | viability | p53 | CYTOCHROME-C | LNCaP cells | ONCOLOGY | SP-A | GROWTH | PC3 cells | EXPRESSION | pattern recognition receptor | PROGRESSION | Treatment outcome | Care and treatment | Analysis | Cancer cells | Genetic aspects | Research | Prostate cancer | Androgens | Gene expression | Apoptosis
Journal Article