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Nature Biotechnology, ISSN 1087-0156, 03/2010, Volume 28, Issue 3, pp. 271 - 274
Journal Article
Journal Article
Human Gene Therapy, ISSN 1043-0342, 03/2018, Volume 29, Issue 3, pp. 285 - 298
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, pp. e0203398 - e0203398
Objectives Spinal muscular atrophy (SMA) is a devastating motor neuron disorder caused by homozygous loss of the survival motor neuron 1 (SMN1) gene and... 
RHEUMATOID-ARTHRITIS | SURVIVAL | GENE | FATTY LIVER-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IMPAIRED ENDOCYTOSIS | SERUM FETUIN | OLIGOMERIC MATRIX PROTEIN | MOTOR-NEURON PROTEIN | CARTILAGE | Biomarkers - metabolism | Muscular Atrophy, Spinal - metabolism | Oligodeoxyribonucleotides, Antisense - pharmacology | Membrane Glycoproteins - biosynthesis | Muscular Atrophy, Spinal - pathology | Membrane Glycoproteins - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Muscular Atrophy, Spinal - genetics | Microfilament Proteins - biosynthesis | Animals | Survival of Motor Neuron 1 Protein - antagonists & inhibitors | Muscular Atrophy, Spinal - therapy | Survival of Motor Neuron 1 Protein - genetics | Mice | Survival of Motor Neuron 1 Protein - biosynthesis | Microfilament Proteins - genetics | Research | Biological markers | Gene expression | Drug therapy | Spinal muscular atrophy | Therapy | Immunoassay | SMN protein | Oligonucleotides | Vitronectin | Motors | Feasibility analysis | Cartilage oligomeric matrix protein | Proteins | Atrophy | Cartilage | Biomedical materials | Genetics | Biocompatibility | Bioindicators | Matrix protein | Phenotypes | Liver diseases | Peptidase | Cell survival | Glycoprotein | Feasibility studies | Osteopontin | Antisense oligonucleotides | Medicine | Medical prognosis | Biomarkers | Alzheimers disease | Index Medicus
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2016, Volume 111, pp. 58 - 75
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by motor neurons degeneration and muscular atrophy. There is no... 
Neuroprotection | Loganin | IGF-1 | Muscular atrophy | Survival motor neuron protein | Akt/mTOR | MUSCLE ATROPHY | DIABETIC-NEPHROPATHY | CORNI-FRUCTUS | IMPROVES SURVIVAL | UBIQUITIN LIGASES | SINGLE NUCLEOTIDE | MOTOR-NEURON PROTEIN | SIGNALING PATHWAY | MOUSE MODEL | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | Fibroblasts - enzymology | Phosphorylation | Protein Biosynthesis | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Humans | Muscular Atrophy, Spinal - enzymology | Motor Activity - drug effects | Motor Neurons - pathology | Dose-Response Relationship, Drug | Muscular Atrophy, Spinal - genetics | Neuroprotective Agents - pharmacology | Transfection | RNA Interference | Time Factors | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Survival of Motor Neuron 1 Protein - genetics | Weight Gain - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Muscular Atrophy, Spinal - physiopathology | Motor Neurons - drug effects | Cytoprotection | Disease Models, Animal | Cell Line | Genetic Predisposition to Disease | Muscle, Skeletal - enzymology | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | SKP Cullin F-Box Protein Ligases - metabolism | Motor Neurons - enzymology | Fibroblasts - pathology | Phenotype | Animals | Signal Transduction - drug effects | Iridoids - pharmacology | Fibroblasts - drug effects | Muscular Atrophy, Spinal - drug therapy | Mice | Muscle Strength - drug effects | Survival of Motor Neuron 1 Protein - biosynthesis | Tripartite Motif Proteins - metabolism | Muscle, Skeletal - pathology | Mutation | Nerve Degeneration | Insulin-Like Growth Factor I - metabolism | Medical colleges | Protein biosynthesis | Pharmacy | Glycogen | Analysis | Diabetic nephropathies | Models | Protein kinases | Protein binding | Spinal muscular atrophy | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 03/2017, Volume 26, Issue 5, pp. 932 - 941
Journal Article
neurogenetics, ISSN 1364-6745, 2/2010, Volume 11, Issue 1, pp. 27 - 40
Journal Article