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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 25, pp. 10337 - 10342
Spinal muscular atrophy (SMA), caused by the deletion of the SMN1 gene, is the leading genetic cause of infant mortality. SMN protein is present at high levels... 
Axons | Motor neurons | Growth cones | Neuroscience | Messenger RNA | RNA | Neurons | Antibodies | Gene expression regulation | SMN complex proteins | Neuritin | Local protein synthesis | Embryonic lethal abnormal vision drosophila-like 4 (ELAV-L4) | LOCALIZATION | RIBONUCLEOPROTEIN | MULTIDISCIPLINARY SCIENCES | ACTIVITY-DEPENDENT EXPRESSION | IDENTIFICATION | neuritin | GROWTH CONES | TRANSPORT | DETERMINING GENE-PRODUCT | SPINAL MUSCULAR-ATROPHY | IN-VIVO | ASSOCIATION | embryonic lethal abnormal vision Drosophila-like 4 (ELAV-L4) | local protein synthesis | ELAV-Like Protein 4 | Humans | RNA, Messenger - metabolism | Zebrafish - embryology | Recombinant Fusion Proteins - metabolism | Embryo, Mammalian - anatomy & histology | Motor Neurons - cytology | Survival of Motor Neuron 1 Protein - genetics | Neuropeptides - genetics | Animals, Genetically Modified | RNA, Messenger - genetics | Cells, Cultured | ELAV Proteins - metabolism | Axons - metabolism | Neuropeptides - metabolism | Survival of Motor Neuron 1 Protein - metabolism | Nerve Tissue Proteins - genetics | GPI-Linked Proteins - metabolism | Motor Neurons - metabolism | Nerve Tissue Proteins - metabolism | Embryo, Mammalian - physiology | Animals | Axons - pathology | Recombinant Fusion Proteins - genetics | Zebrafish - physiology | Mice | ELAV Proteins - genetics | GPI-Linked Proteins - genetics | Gene mutations | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Spinal muscular atrophy | Proteins | Genotype & phenotype | Neuromuscular diseases | Zebrafish | Infant mortality | Ribonucleic acid--RNA | Index Medicus | Spinal cord | Translation | Cell survival | Mental disorders | Axonogenesis | Mortality | SMN protein | survival | Mass spectroscopy | Infants | Gene deletion | infant mortality | HuD protein | Pathology | RNA-binding protein | Actin | Neuromuscular junctions | spinal muscular atrophy | Axon guidance | Mass spectrometry | Biological Sciences
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