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JAMA, ISSN 0098-7484, 12/2003, Volume 290, Issue 21, pp. 2805 - 2816
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 04/2016, Volume 124, Issue 4, pp. 542 - 549
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87548
Background: Inhibition of the transporter-mediated hepatobiliary elimination of bile salts is a putative mechanism for liver toxicity observed with some... 
BILE-ACID TRANSPORT | IN-VITRO | RAT HEPATOCYTES | PULMONARY ARTERIAL-HYPERTENSION | SALT EXPORT PUMP | BILIARY-EXCRETION | MULTIDISCIPLINARY SCIENCES | HEPATIC-UPTAKE | KNOCKOUT MICE | FAMILIAL INTRAHEPATIC CHOLESTASIS | P-GLYCOPROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Middle Aged | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Bile - metabolism | Male | Hepatocytes - metabolism | Pyridazines - pharmacology | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Liver - drug effects | Organic Anion Transporters, Sodium-Independent - metabolism | ATP-Binding Cassette Transporters - metabolism | Adult | Female | Membrane Transport Proteins - metabolism | Endothelin Receptor Antagonists | Hepatocytes - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | Taurocholic Acid - pharmacology | Liver - metabolism | Receptors, Endothelin - metabolism | Thiophenes - pharmacology | Bile Acids and Salts - metabolism | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Symporters - metabolism | Isoxazoles - pharmacology | Phenylpropionates - pharmacology | Bile - drug effects | Solute Carrier Organic Anion Transporter Family Member 1b1 | Multidrug Resistance-Associated Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Drug resistance in microorganisms | Endothelin | Bile acids | Research | Analysis | Salts | Transplants & implants | Toxicity | Pathogenesis | Liver | Gallbladder diseases | Accumulation | Bioaccumulation | Rodents | Protein transport | P-Glycoprotein | Efflux | Polypeptides | Mortality | Multidrug resistance | Glycoprotein | Substrate inhibition | Breast cancer | Substrates | Bile salts | Organic anion transporting polypeptide | Molecular modelling | Acids | Sodium | Hepatocytes | Transporter | Cancer | Bile
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 06/2010, Volume 88, Issue 6, pp. 682 - 691
To evaluate potential mechanisms of clinical hepatotoxicity, 4 endothelin receptor antagonists (ERAs) were examined for substrate activity and inhibition of... 
Hepatic transport | BSEP | Endothelin | Transporter substrate | Pulmonary artery hypertension | Endothelin receptor antagonists | OATP | PHARMACOKINETIC INTERACTION | PHYSIOLOGY | pulmonary artery hypertension | RAT HEPATOCYTES | PULMONARY ARTERIAL-HYPERTENSION | SALT EXPORT PUMP | transporter substrate | HEPATIC-UPTAKE | endothelin receptor antagonists | CLINICAL-PRACTICE GUIDELINES | endothelin | CYCLOSPORINE-A | THERAPY | BILIARY-EXCRETION | KETOCONAZOLE | PHARMACOLOGY & PHARMACY | hepatic transport | Antihypertensive Agents - pharmacology | Estradiol - analogs & derivatives | Taurocholic Acid - metabolism | Humans | Middle Aged | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Male | Thiophenes - metabolism | Antihypertensive Agents - metabolism | Hepatocytes - metabolism | Pyridazines - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Organic Anion Transporters - metabolism | Pyrimidines - metabolism | Young Adult | Phenylpropionates - metabolism | Symporters - antagonists & inhibitors | ATP-Binding Cassette Transporters - metabolism | Adult | Female | Pyridazines - metabolism | Biological Transport - drug effects | Cell Culture Techniques | Endothelin Receptor Antagonists | Hepatocytes - drug effects | Estradiol - metabolism | Organic Anion Transporters - antagonists & inhibitors | Isoxazoles - metabolism | Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors | Cells, Cultured | Thiophenes - pharmacology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Symporters - metabolism | Isoxazoles - pharmacology | Phenylpropionates - pharmacology | ATP Binding Cassette Subfamily B Member 11 | Enkephalin, D-Penicillamine (2,5)- - metabolism | Adolescent | Sulfonamides - metabolism | Aged | Multidrug Resistance-Associated Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Cell receptors | Genetic aspects | Research | Diagnosis | Properties | Health aspects | Liver cells | Pulmonary hypertension
Journal Article
Journal of Hypertension, ISSN 0263-6352, 08/2011, Volume 29, Issue 8, pp. 1649 - 1659
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2013, Volume 368, Issue 7, pp. 623 - 632
Inhibition of mitogen-activated protein kinase resulted in an increase in expression of the sodium–iodide symporter in 12 of 20 patients, 8 of whom had... 
CELLS | MEDICINE, GENERAL & INTERNAL | ACTIVATION | THERAPY | BRAF MUTATIONS | PHASE-II | PAPILLARY | DIFFERENTIATION | RADIOACTIVE IODINE | CARCINOMA | EXPRESSION | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Multimodal Imaging | Iodine Radioisotopes - therapeutic use | Neoplasm Metastasis | Thyrotropin Alfa - pharmacology | Adult | Female | Radiometry | Benzimidazoles - therapeutic use | MAP Kinase Kinase 1 - antagonists & inhibitors | Thyroid Neoplasms - radiotherapy | Iodine Radioisotopes - pharmacokinetics | Symporters - metabolism | Thyroid Neoplasms - genetics | MAP Kinase Kinase 2 - antagonists & inhibitors | Benzimidazoles - pharmacology | Aged | Symporters - drug effects | Mutation | Mitogen-Activated Protein Kinases - metabolism | Thyroid Neoplasms - pathology | Drugs | Dose-response relationship (Biochemistry) | Care and treatment | Thyroid cancer | Product/Service Evaluations | Dosage and administration | Drug therapy | Isotopes | Methods | Cancer | Iodine | Animal models | MAP kinase | Antagonists | Thyroid gland | Kinases | Cancer therapies | Patients | Myelodysplastic syndrome | Metastases | Thyroid-stimulating hormone | Sodium | Thyroglobulin | Protein kinase | Dosimetry | Positron emission tomography | Thyroid | Tumors | Index Medicus | Abridged Index Medicus
Journal Article