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Neuroscience, ISSN 0306-4522, 2008, Volume 155, Issue 2, pp. 423 - 438
Abstract Nutrient transporters and ABC efflux pumps at the blood–brain barrier are major determinants of drug penetration into the brain. Immunohistochemical... 
Neurology | abluminal | cerebral microvessels | luminal | ABC transporter | choroid plexus | NEUROSCIENCES | P-GLYCOPROTEIN ABCB1 | MICROVESSEL ENDOTHELIUM | AMINO-ACID TRANSPORTER | ABLUMINAL MEMBRANE | GLUCOSE-TRANSPORTER | RESISTANCE-ASSOCIATED PROTEIN-1 | CENTRAL-NERVOUS-SYSTEM | CAPILLARY ENDOTHELIAL-CELLS | CHOROID-PLEXUS | MULTIDRUG TRANSPORTERS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Ependyma - blood supply | Cerebrovascular Circulation - physiology | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Choroid Plexus - metabolism | Glucose Transporter Type 1 - metabolism | Male | Gene Expression Profiling | Choroid Plexus - ultrastructure | Blood-Brain Barrier - ultrastructure | Microcirculation - physiology | Choroid Plexus - blood supply | Monocarboxylic Acid Transporters - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Blood-Brain Barrier - physiology | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Cell Line | Biotinylation | Rats | Ependyma - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Kidney - cytology | Rats, Sprague-Dawley | Blotting, Western | Symporters - metabolism | Animals | Glucose Transporter Type 1 - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Symporters - genetics | Microcirculation - ultrastructure | Monocarboxylic Acid Transporters - genetics | Multidrug Resistance-Associated Proteins - metabolism | Ependyma - ultrastructure | Phosphates | Glucose metabolism | Brain | Fluorescein | Biotin | Glucose | Drug resistance | Intermediate filament proteins | Dextrose | Protein binding | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 03/2006, Volume 113, Issue 9, pp. 1213 - 1225
Journal Article
Clinical Trials, ISSN 1740-7745, 10/2014, Volume 11, Issue 5, pp. 532 - 546
Background: High blood pressure is an important public health concern because it is highly prevalent and a risk factor for adverse health outcomes, including... 
Hypertension | Stroke | Randomized clinical trial | Brain structure and function | Cardiovascular | Major adverse cardiovascular outcomes | Blood pressure targets | Cognition | Kidney | Geriatrics | GLOBAL BURDEN | MEDICINE, RESEARCH & EXPERIMENTAL | cognition | brain structure and function | FEMALE SEXUAL FUNCTION | VALIDATION | INDEX FSFI | cardiovascular | stroke | STROKE RISK-FACTORS | blood pressure targets | kidney | geriatrics | major adverse cardiovascular outcomes | DOUBLE-BLIND | CORONARY-HEART-DISEASE | hypertension | COGNITIVE ASSESSMENT | ISCHEMIC-STROKE | Sodium Potassium Chloride Symporter Inhibitors - therapeutic use | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Clinical Protocols | Hypertension - drug therapy | Male | Treatment Outcome | Renal Insufficiency, Chronic - complications | Sodium Chloride Symporter Inhibitors - therapeutic use | Systole | Antihypertensive Agents - therapeutic use | Patient Care Planning | Cardiovascular Diseases - complications | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Aged, 80 and over | Hypertension - complications | Female | Aged | Angiotensin Receptor Antagonists - therapeutic use | Adrenergic beta-Antagonists - therapeutic use | Clinical trials | Design of experiments | Research methodology | Myocardial infarction | Heart | Intervention | End-stage renal disease | Cognitive ability | Cardiovascular disease | Blood | Risk factors | Subgroups | Recruitment | Cost-benefit analysis | Randomization | Ischemia | Minorities | Developmental stages | Dementia disorders | Blood pressure | Cerebral ischemic disease | Heart diseases | Public health | Age | Heart failure | Cerebral infarction | Risk groups | Complications | Health risks | Disease control | Coronary artery disease | Glomerular filtration rate | Renal failure | Infarction | Kidney diseases | Acute coronary syndromes | Cardiovascular diseases | Mercury | Kidney transplantation | Index Medicus
Journal Article
The Lancet, ISSN 0140-6736, 09/2005, Volume 366, Issue 9489, pp. 895 - 906
The apparent shortfall in prevention of coronary heart disease (CHD) noted in early hypertension trials has been attributed to disadvantages of the diuretics... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | MANAGEMENT | MORBIDITY | DISEASE | GUIDELINES | DOUBLE-BLIND | CALCIUM-ANTAGONISTS | HYPERTENSION | INTERVENTION | Calcium Channel Blockers - adverse effects | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antihypertensive Agents - administration & dosage | Bendroflumethiazide - administration & dosage | Hypertension - drug therapy | Male | Perindopril - administration & dosage | Sodium Chloride Symporter Inhibitors - administration & dosage | Diuretics | Adrenergic beta-Antagonists - adverse effects | Adult | Female | Blood Pressure - drug effects | Atenolol - administration & dosage | Drug Therapy, Combination | Amlodipine - administration & dosage | Adrenergic beta-Antagonists - administration & dosage | Risk Factors | Amlodipine - adverse effects | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Antihypertensive Agents - adverse effects | Coronary Disease - prevention & control | Calcium Channel Blockers - administration & dosage | Atenolol - adverse effects | Hypertension - complications | Aged | Hypertension | Antihypertensive drugs | Evaluation | Dosage and administration | Drug therapy | Prevention | Drug therapy, Combination | Health aspects | Coronary heart disease | Risk factors | Studies | Drugs | Cardiovascular disease | Medical treatment | Myocardial infarction | Heart attacks | Clinical trials | Family medical history | Blood | Randomization | Motivation | Blood pressure | Heart diseases | Antihypertensive agents | Cerebral infarction | Stroke | Fasting | Mortality | Diabetes mellitus | Health risks | Triglycerides | Metabolism | Risk analysis | Atenolol | Fatal | Patients | Coronary artery disease | Cholesterol | Heart rate | Infarction | Diabetes | Cardiovascular diseases | Health risk assessment | Potassium | Index Medicus | Abridged Index Medicus | Amlodipine/administration & dosage/adverse effects | Bendroflumethiazide/administration & dosage | Cardiovascular Diseases/prevention & control | Perindopril/administration & dosage | MEDICIN OCH HÄLSOVETENSKAP | Atenolol/administration & dosage/adverse effects | Combination | Antihypertensive Agents/administration & dosage/adverse effects | Angiotensin-Converting Enzyme Inhibitors/administration & dosage | MEDICAL AND HEALTH SCIENCES | Coronary Disease/prevention & control | Drug Therapy | Adrenergic beta-Antagonists/administration & dosage/adverse effects | Blood Pressure/drug effects | Hypertension/complications/drug therapy | Calcium Channel Blockers/administration & dosage/adverse effects | Sodium Chloride Symporter Inhibitors/administration & dosage
Journal Article
ISSN 1420-682X, 2017
Hypertension (high blood pressure) is a major public health problem affecting more than a billion people worldwide with complications, including stroke, heart... 
Hypertension | Blood Pressure | Animals | Signal Transduction | Pseudohypoaldosteronism | Cullin Proteins | Humans | Protein-Serine-Threonine Kinases | Sodium-Potassium-Chloride Symporters | Receptors, Drug | Neovascularization, Physiologic | Sodium Chloride Symporters
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2012, Volume 436, Issue 1-2, pp. 508 - 518
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