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Nature (London), ISSN 1476-4687, 2011, Volume 472, Issue 7344, pp. 466 - 470
... by interventions that are associated with beneficial effects on cognition and mood, such as learning... 
DEPRESSION | MODELS | MEMORY | MULTIDISCIPLINARY SCIENCES | NEURONS | DISORDER | DENTATE GYRUS | MATURATION | SYNAPTIC PLASTICITY | FLUOXETINE | BRAIN | Apoptosis - drug effects | Learning - drug effects | Neuronal Plasticity - drug effects | Male | Neural Stem Cells - cytology | Anxiety - therapy | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Exploratory Behavior - drug effects | Cognition - physiology | Long-Term Potentiation - physiology | Antidepressive Agents - pharmacology | bcl-2-Associated X Protein - deficiency | Extinction, Psychological - physiology | Cell Survival - drug effects | Synapses - drug effects | Conditioning, Classical - drug effects | Affect - physiology | bcl-2-Associated X Protein - metabolism | Anxiety - physiopathology | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Mice, Knockout | Dentate Gyrus - cytology | Aging - physiology | Dentate Gyrus - physiology | Mice | Dentate Gyrus - pathology | Hippocampus - physiopathology | Memory - physiology | Memory - drug effects | Aging - drug effects | Extinction, Psychological - drug effects | Fear - physiology | Dentate Gyrus - physiopathology | Exploratory Behavior - physiology | Synapses - metabolism | Fear - psychology | Female | Neurogenesis - drug effects | bcl-2-Associated X Protein - genetics | Neural Stem Cells - drug effects | Hippocampus - cytology | Physical Conditioning, Animal - physiology | Conditioning, Classical - physiology | Aging - pathology | Learning - physiology | Animals | Neurogenesis - physiology | Models, Neurological | Hippocampus - physiology | Neural Stem Cells - metabolism | Physiological aspects | Hippocampus (Brain) | Neurogenesis | Health aspects | Proteins | Studies | Young adults | Cognition & reasoning | Neurons | Anxieties | Rodents | Behavior
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2002, Volume 110, Issue 4, pp. 429 - 441
The adult brain is extremely vulnerable to various insults. The recent discovery of neural progenitors in adult mammals, however, raises the possibility of... 
RAT SPINAL-CORD | GERBIL HIPPOCAMPUS | STEM-CELLS | TRANSIENT FOREBRAIN ISCHEMIA | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROBLAST-GROWTH-FACTOR | CENTRAL-NERVOUS-SYSTEM | ADULT MAMMALIAN BRAIN | SUBVENTRICULAR ZONE | SYNAPTIC PLASTICITY | CELL BIOLOGY | Neural Pathways - drug effects | Recovery of Function - drug effects | Nerve Regeneration - physiology | Neuronal Plasticity - drug effects | Male | Dendrites - ultrastructure | Nerve Degeneration - metabolism | Neuronal Plasticity - physiology | Recovery of Function - physiology | Hippocampus - ultrastructure | Pyramidal Cells - drug effects | Organ Culture Techniques | Dendrites - drug effects | Synapses - drug effects | Neural Pathways - growth & development | Rats | Synapses - ultrastructure | Brain Ischemia - physiopathology | Cell Division - drug effects | Stem Cells - ultrastructure | Cell Division - physiology | Cell Movement - drug effects | Brain Ischemia - drug therapy | Nerve Regeneration - drug effects | Growth Substances - pharmacology | Pyramidal Cells - metabolism | Rats, Wistar | Microtubule-Associated Proteins - metabolism | Nerve Degeneration - physiopathology | Brain Ischemia - metabolism | Hippocampus - drug effects | Stem Cells - metabolism | Excitatory Postsynaptic Potentials - drug effects | Cell Movement - physiology | Excitatory Postsynaptic Potentials - physiology | Synapses - metabolism | Up-Regulation - physiology | Hippocampus - growth & development | Pyramidal Cells - ultrastructure | Dendrites - metabolism | Transcription Factors - genetics | Microscopy, Electron | Transcription Factors - metabolism | Up-Regulation - drug effects | Animals | Growth Substances - therapeutic use | Stem Cells - drug effects | Neural Pathways - ultrastructure | Nerve Degeneration - drug therapy | Neural circuitry | Neurons | Growth | Physiological aspects | Hippocampus (Brain) | Developmental neurology | Research
Journal Article
Neuron, ISSN 0896-6273, 2007, Volume 56, Issue 4, pp. 701 - 713
Acetylcholine is a ubiquitous cortical neuromodulator implicated in cognition. In order to understand the potential for acetylcholine to play a role in visual... 
SYSNEURO | SIGNALING | ACETYLCHOLINE-RECEPTORS | CORTICAL-NEURONS | CAT VISUAL-CORTEX | MONKEY STRIATE CORTEX | CHOLINERGIC MODULATION | CONTRAST RESPONSE FUNCTIONS | SPATIAL ATTENTION | NEUROSCIENCES | CEREBRAL-CORTEX | GABAERGIC NEURONS | MACACA-FASCICULARIS | Pyramidal Cells - metabolism | Synaptic Transmission - physiology | Visual Perception - drug effects | gamma-Aminobutyric Acid - metabolism | Visual Pathways - metabolism | Macaca fascicularis | Male | Acetylcholine - metabolism | Geniculate Bodies - drug effects | Nicotine - pharmacology | Neural Inhibition - physiology | Neurons - ultrastructure | Synapses - metabolism | Synaptic Transmission - drug effects | Neurons - metabolism | Pyramidal Cells - drug effects | Neurons - drug effects | Pyramidal Cells - ultrastructure | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microscopy, Electron, Transmission | Synapses - drug effects | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Contrast Sensitivity - physiology | Visual Perception - physiology | Geniculate Bodies - metabolism | Interneurons - ultrastructure | Geniculate Bodies - ultrastructure | Interneurons - drug effects | Synapses - ultrastructure | Animals | Interneurons - metabolism | Visual Pathways - drug effects | Visual Pathways - ultrastructure | Contrast Sensitivity - drug effects | Visual Cortex - ultrastructure | Visual Cortex - drug effects | Visual Cortex - metabolism | Neural Inhibition - drug effects | GABA | Neurons | Nicotine | Brain | Rodents
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 13, pp. 2549 - 2566
DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when... 
MEDICINE, RESEARCH & EXPERIMENTAL | HERPES-SIMPLEX-VIRUS | IN-VITRO | DENDRITIC CELLS | LEUKOCYTE MIGRATION | VARICELLA-ZOSTER-VIRUS | RM CELLS | TISSUE | IMMUNOLOGY | ALDRICH-SYNDROME PROTEIN | MEMORY T-CELLS | IMMUNOLOGICAL SYNAPSES
Journal Article
Sleep Medicine Reviews, ISSN 1087-0792, 2012, Volume 17, Issue 3, pp. 227 - 238
Summary This review considers recent evidence showing that cells in the reticular activating system (RAS) exhibit 1) electrical coupling mainly in GABAergic... 
Neurology | Sleep Medicine | Subthreshold oscillations | Calcium channels | Gamma band | Modafinil | Gap junctions | Arousal | ELECTRICAL SYNAPSES | MESOPONTINE CHOLINERGIC NUCLEI | THALAMIC NEURONS | GAMMA-OSCILLATIONS | NEURONAL OSCILLATIONS | PARADOXICAL SLEEP | NEUROSCIENCES | CLINICAL NEUROLOGY | ENTORHINAL CORTEX | CALCIUM-CHANNELS | THALAMOCORTICAL ACTIVITY | SLEEP INDUCTION ZONE | Wakefulness - drug effects | Central Nervous System Stimulants - pharmacology | Neural Pathways - drug effects | Synaptic Transmission - physiology | Reticular Formation - drug effects | Humans | Locus Coeruleus - drug effects | Sodium Channels - physiology | Intralaminar Thalamic Nuclei - physiopathology | Cerebral Cortex - physiopathology | gamma-Aminobutyric Acid - physiology | Calcium Channels - physiology | Locus Coeruleus - physiopathology | Neurons - physiology | Reticular Formation - physiopathology | Beta Rhythm - physiology | Signal Processing, Computer-Assisted | Synaptic Transmission - drug effects | Cerebral Cortex - drug effects | Neural Pathways - physiopathology | Sleep - physiology | Neurons - drug effects | Calcium Channels - drug effects | Pons - physiopathology | Pedunculopontine Tegmental Nucleus - physiopathology | Awareness - drug effects | Awareness - physiology | Sodium Channels - drug effects | Sleep - drug effects | Beta Rhythm - drug effects | Animals | Electroencephalography - drug effects | Intralaminar Thalamic Nuclei - drug effects | Wakefulness - physiology | Benzhydryl Compounds - pharmacology | Pedunculopontine Tegmental Nucleus - drug effects | GABA
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 500, Issue 7463, pp. 422 - 426
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 11, pp. e0142340 - e0142340
.... Here, we used an adeno-associated viral vector-based mouse model of early-stage AD-type tauopathy to investigate effects of the mTOR inhibitor and autophagy stimulator rapamycin on the tau-driven... 
MAMMALIAN TARGET | IN-VITRO | STIMULATION | MULTIDISCIPLINARY SCIENCES | MEMORY IMPAIRMENT | DISEASE | TAU | ENTORHINAL CORTEX NEURONS | TOXICITY | AUTOPHAGY | PATHOLOGY | Microglia - metabolism | Entorhinal Cortex - metabolism | Humans | tau Proteins - metabolism | Male | Hippocampus - drug effects | Neurodegenerative Diseases - drug therapy | TOR Serine-Threonine Kinases - antagonists & inhibitors | Synapses - metabolism | Dentate Gyrus - drug effects | Perforant Pathway - metabolism | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Disease Models, Animal | Synapses - drug effects | Dentate Gyrus - metabolism | Microglia - drug effects | Alzheimer Disease - drug therapy | Axons - drug effects | Axons - metabolism | Memory, Long-Term - drug effects | Entorhinal Cortex - drug effects | Neurodegenerative Diseases - metabolism | Sirolimus - pharmacology | Hippocampus - metabolism | Tauopathies - metabolism | Animals | Perforant Pathway - drug effects | Alzheimer Disease - metabolism | Mice | Tauopathies - drug therapy | TOR protein | Brain | Phosphorylation | Toxicity | Activation | mRNA | Kinases | Autophagy | Neurotoxicity | Neurodegeneration | Rodents | Long term memory | Degeneration | Inhibition | Alzheimer's disease | Neurodegenerative diseases | Neurons | Astrocytes | Rapamycin | Inflammation | Substrates | Microglia | Pathology | Cortex (entorhinal) | Dentate gyrus | Gliosis | Inhibitors | Tau protein | Mutation | Hippocampus | Phagocytosis | Synapses | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 4, pp. 1337 - 1347
Different GABAergic interneuron types have specific roles in hippocampal function, and anatomical as well as physiological features vary greatly between... 
BISTRATIFIED INTERNEURONS | INHIBITORY INTERNEURONS | NETWORK OSCILLATIONS | PERISOMATIC INHIBITION | EXCITATORY SYNAPSES | POSITIVE INTERNEURONS | RAT HIPPOCAMPUS | OSCILLATIONS IN-VIVO | SYNAPTIC PLASTICITY | NEUROSCIENCES | GABAERGIC NEURONS | Immunohistochemistry | Synaptic Transmission - physiology | gamma-Aminobutyric Acid - metabolism | Calcium Signaling - physiology | Neuronal Plasticity - drug effects | Parvalbumins - metabolism | Male | Dendrites - ultrastructure | Hippocampus - drug effects | Long-Term Synaptic Depression - drug effects | Presynaptic Terminals - ultrastructure | Neural Inhibition - physiology | Neuronal Plasticity - physiology | Synapses - metabolism | Long-Term Potentiation - drug effects | Long-Term Potentiation - physiology | Synaptic Transmission - drug effects | Cell Polarity - drug effects | Interneurons - cytology | Organ Culture Techniques | Receptors, AMPA - metabolism | Dendrites - drug effects | Dendrites - metabolism | Long-Term Synaptic Depression - physiology | Synapses - drug effects | Presynaptic Terminals - drug effects | Interneurons - drug effects | Rats | Synapses - ultrastructure | Hippocampus - cytology | Rats, Sprague-Dawley | Hippocampus - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Patch-Clamp Techniques | Animals | Interneurons - metabolism | Calcium Signaling - drug effects | Receptor, Cannabinoid, CB1 - drug effects | Presynaptic Terminals - metabolism | Cell Polarity - physiology | Glutamic Acid - metabolism | Cell Shape - physiology | Neural Inhibition - drug effects | Receptors, AMPA - drug effects
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 489, Issue 7414, pp. 150 - 154
Journal Article