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Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 65, Issue 3, pp. 320 - 327
Endocannabinoids are released from postsynaptic neurons and cause retrograde suppression of synaptic transmission. Anandamide and 2-arachidonoylglycerol (2-AG)... 
SYSNEURO | MOLNEURO | SIGNALING | SYSTEM | ENDOGENOUS CANNABINOIDS | DEPOLARIZATION | ACTIVATION | PRESYNAPTIC INHIBITION | GABA RELEASE | METABOTROPIC GLUTAMATE RECEPTORS | CANNABINOID CB1 RECEPTOR | NEUROSCIENCES | BRAIN | HIPPOCAMPAL SYNAPSES | Synaptic Transmission - physiology | Synaptic Transmission - genetics | Calcium - metabolism | Cerebellum - drug effects | Hippocampus - drug effects | Cerebellum - physiology | Corpus Striatum - cytology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Neural Inhibition - physiology | Arachidonic Acids - metabolism | Inhibitory Postsynaptic Potentials - genetics | Potassium Chloride - pharmacology | Lipoprotein Lipase - classification | Neurons - physiology | Statistics, Nonparametric | Synaptic Transmission - drug effects | Glycerol - analogs & derivatives | Neurons - drug effects | Electric Stimulation - methods | Lipoprotein Lipase - metabolism | Endocannabinoids | Excitatory Postsynaptic Potentials - genetics | Animals, Newborn | Neural Inhibition - genetics | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cells, Cultured | Lipoprotein Lipase - deficiency | Hippocampus - cytology | Polyunsaturated Alkamides - metabolism | Mice, Knockout | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Animals | Glycerol - metabolism | Cerebellum - cytology | Corpus Striatum - drug effects | Corpus Striatum - physiology | Mice | Hippocampus - physiology | In Vitro Techniques | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2012, Volume 32, Issue 26, pp. 8767 - 8777
Alzheimer's disease (AD) is the major cause of dementia. During the development of AD, neurofibrillary tangles progress in a fixed pattern, starting in the... 
PRION PROTEIN | CELLS | TRANSPORT | ALZHEIMERS-DISEASE | MECHANISMS | PRECURSOR PROTEIN | NEUROSCIENCES | BRAIN | OLIGOMERS | PEPTIDE | PARKINSONS-DISEASE | Membrane Glycoproteins - metabolism | Coculture Techniques | Humans | Cell Communication - physiology | Male | Green Fluorescent Proteins - genetics | rab5 GTP-Binding Proteins - metabolism | Neurons - ultrastructure | Time Factors | Amyloid beta-Peptides - metabolism | Synaptic Transmission - drug effects | Neurons - metabolism | Animals, Newborn | Microinjections | Endocytosis - drug effects | Rats | Rats, Sprague-Dawley | Nerve Degeneration - pathology | Patch-Clamp Techniques | Cell Communication - drug effects | Lysosomal-Associated Membrane Protein 2 - metabolism | Heterocyclic Compounds, 3-Ring - metabolism | Synaptic Transmission - physiology | Peptide Fragments - toxicity | Exocytosis - physiology | Exocytosis - drug effects | Nerve Degeneration - chemically induced | Neuroglia - drug effects | Dose-Response Relationship, Drug | Tetrazolium Salts | Transfection | Thiazoles | Female | Neurons - drug effects | Neuroblastoma - pathology | Dendrites - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Peptide Fragments - metabolism | Amyloid beta-Peptides - toxicity | Cells, Cultured | Hippocampus - cytology | Endocytosis - physiology | Nerve Tissue Proteins - metabolism | Animals | Cell Differentiation - drug effects | Heterocyclic Compounds, 3-Ring - administration & dosage | Neocortex - cytology | Neuroglia - metabolism | Index Medicus | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 02/2011, Volume 16, Issue 2, pp. 156 - 170
Corticosteroid stress hormones have a strong impact on the function of prefrontal cortex (PFC), a central region controlling cognition and emotion, though the... 
working memory | SGK | acute stress | Rab4 | AMPA receptors | corticosterone | NMDA receptors | LIFE-SPAN | AMPA RECEPTOR TRAFFICKING | ENDOCYTIC PATHWAY | PSYCHIATRY | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MINERALOCORTICOID RECEPTORS | SERUM | SYNAPTIC PLASTICITY | NEUROSCIENCES | PREFRONTAL CORTEX | LONG-TERM DEPRESSION | INDUCIBLE KINASE ISOFORMS | Receptors, Glutamate - metabolism | Corticosterone - pharmacology | Electric Stimulation | Prefrontal Cortex - physiopathology | Male | rab GTP-Binding Proteins - genetics | Green Fluorescent Proteins - genetics | Memory, Short-Term - physiology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Immediate-Early Proteins - metabolism | Drug Interactions | Prefrontal Cortex - drug effects | Transfection - methods | Long-Term Potentiation - drug effects | Time Factors | Pyramidal Cells - physiology | Excitatory Amino Acid Agents - pharmacology | Synaptic Transmission - drug effects | Pyramidal Cells - drug effects | Excitatory Postsynaptic Potentials - genetics | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | rab GTP-Binding Proteins - metabolism | Maze Learning - physiology | Receptors, Glutamate - genetics | Gene Expression Regulation - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Rats | Memory, Short-Term - drug effects | Biophysics | Maze Learning - drug effects | Prefrontal Cortex - cytology | Rats, Sprague-Dawley | Hormone Antagonists - pharmacology | Peptides - pharmacology | Gene Expression Regulation - drug effects | Stress, Psychological - pathology | Animals | Immediate-Early Proteins - genetics | Glutamic Acid - metabolism | In Vitro Techniques | Mifepristone - pharmacology | Stress, Psychological - physiopathology | Psychological aspects | Methyl aspartate | Short-term memory | Physiological aspects | Genetic aspects | Research | Stress (Psychology) | Risk factors | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2015, Volume 373, Issue 1, pp. 8 - 9
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2011, Volume 69, Issue 8, pp. 754 - 761
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2009, Volume 29, Issue 41, pp. 12982 - 12993
Estrogen, in addition to its genomic effects in brain, causes rapid and reversible changes to synaptic operations. We report here that these acute actions are... 
SPRAGUE-DAWLEY RATS | INDUCED INCREASE | DENDRITIC SPINE DENSITY | NEUROTROPHIC FACTOR | ACTIN POLYMERIZATION | HIPPOCAMPAL PYRAMIDAL NEURONS | LIM-KINASE | REPLACEMENT THERAPY | LONG-TERM POTENTIATION | NEUROSCIENCES | ESTROUS-CYCLE | Estradiol - analogs & derivatives | Synaptic Transmission - physiology | Age Factors | Rats, Long-Evans | Actins - metabolism | Neuronal Plasticity - drug effects | Estrogen Antagonists - pharmacology | Male | Neurons - cytology | Ginsenosides - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Sapogenins - pharmacology | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Dendritic Spines - drug effects | Neurons - physiology | Female | Synaptic Transmission - drug effects | Estrogens - metabolism | Neurons - drug effects | Thiazolidines - pharmacology | Electric Stimulation - methods | Estradiol - pharmacology | Phenols - pharmacology | Animals, Newborn | Dendritic Spines - physiology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Ovariectomy - methods | Biophysics | Hippocampus - cytology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Microscopy, Confocal | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Analysis of Variance | Signal Transduction - drug effects | Cytoskeleton - metabolism | Picrotoxin - pharmacology | Oxazoles - pharmacology | In Vitro Techniques | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2010, Volume 30, Issue 9, pp. 3398 - 3408
Striatal dopamine (DA) and acetylcholine (ACh) regulate motivated behaviors and striatal plasticity. Interactions between these neurotransmitters may be... 
KNOCK-OUT MICE | MEDIATED MODULATION | PRIMATE STRIATUM | M2-MUSCARINIC DRUGS | MIDBRAIN DOPAMINE | LONG-TERM POTENTIATION | AUTORECEPTOR FUNCTION | NICOTINIC ACETYLCHOLINE-RECEPTORS | NEUROSCIENCES | CAT CAUDATE-NUCLEUS | MONKEY STRIATUM | Receptor, Muscarinic M2 - genetics | Synaptic Transmission - physiology | Muscarinic Agonists - pharmacology | Nucleus Accumbens - metabolism | Basal Ganglia - metabolism | Receptor, Muscarinic M2 - drug effects | Electrophysiology | Receptors, Muscarinic - metabolism | Acetylcholine - metabolism | Corpus Striatum - cytology | Corpus Striatum - metabolism | Basal Ganglia - cytology | Receptors, Muscarinic - drug effects | Neostriatum - drug effects | Nucleus Accumbens - cytology | Neostriatum - metabolism | Synaptic Transmission - drug effects | Interneurons - cytology | Receptor, Muscarinic M4 - genetics | Dopamine - metabolism | Organ Culture Techniques | Receptors, Muscarinic - genetics | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Neostriatum - cytology | Presynaptic Terminals - drug effects | Receptor, Muscarinic M2 - metabolism | Mice, Inbred C57BL | Interneurons - drug effects | Receptor, Muscarinic M4 - metabolism | Mice, Knockout | Patch-Clamp Techniques | Animals | Interneurons - metabolism | Receptor, Muscarinic M4 - drug effects | Corpus Striatum - drug effects | Presynaptic Terminals - metabolism | Mice | Nucleus Accumbens - drug effects | Basal Ganglia - drug effects | Index Medicus | nicotinic receptors | cholinergic interneurons | caudate-putamen | acetylcholine | nucleus accumbens | M4 mAChRs
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2011, Volume 31, Issue 43, pp. 15340 - 15351
Information processing in the striatum is critical for basal ganglia function and strongly influenced by neuromodulators (e.g., dopamine). The striatum also... 
BASAL GANGLIA | HISTIDINE-DECARBOXYLASE | CHOLINERGIC INTERNEURONS | GABAERGIC INTERNEURONS | CENTRAL-NERVOUS-SYSTEM | PROJECTION NEURONS | FAST-SPIKING INTERNEURONS | RAT-BRAIN | GUINEA-PIG | MEDIUM SPINY NEURONS | NEUROSCIENCES | Tyrosine 3-Monooxygenase - metabolism | Electric Stimulation | Synaptic Transmission - genetics | Channelrhodopsins | Parvalbumins - metabolism | Male | Green Fluorescent Proteins - genetics | Corpus Striatum - cytology | Excitatory Postsynaptic Potentials - drug effects | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Histamine - metabolism | Histamine Agonists - metabolism | Transfection - methods | Inhibitory Postsynaptic Potentials - genetics | Piperidines - pharmacology | Thalamus - physiology | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Histamine Antagonists - pharmacology | Female | Synaptic Transmission - drug effects | Neurons - metabolism | Neurons - drug effects | Excitatory Postsynaptic Potentials - genetics | Histamine - pharmacology | Vesicular Glutamate Transport Protein 1 - metabolism | Mice, Transgenic | Mutation - genetics | Receptors, Dopamine D2 - genetics | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | GABA Agents - pharmacology | Animals | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Feedback, Physiological - drug effects | Mice | Feedback, Physiological - physiology | Histamine Agonists - pharmacology | Hippocampus - physiology | In Vitro Techniques | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Receptors, Dopamine D1 - genetics | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 8, pp. 1083 - 1091
Journal Article