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Arthritis research & therapy, ISSN 1478-6354, 2004, Volume 6, Issue 4, pp. R373 - 383
In the present study, we have shown for the first time that a plant steroid, diosgenin, causes an inhibition of the growth of fibroblast-like synoviocytes from... 
GASTROINTESTINAL TOXICITY | cyclooxygenase-2 | apoptosis | OSTEOSARCOMA CELLS | B SYNOVIOCYTES | RANDOMIZED CONTROLLED-TRIAL | RHEUMATOLOGY | rheumatoid arthritis | CELECOXIB | diosgenin | EXPERIMENTAL OSTEOARTHRITIS | TUMOR-NECROSIS-FACTOR | SYNOVIAL TISSUES | FAMILIAL ADENOMATOUS POLYPOSIS | EXPRESSION | human synoviocyte | Prostaglandin-Endoperoxide Synthases - biosynthesis | Fibroblasts - enzymology | Fibroblasts - secretion | Apoptosis - drug effects | Dinoprostone - biosynthesis | Plant Extracts - pharmacology | Synovial Membrane - enzymology | Cyclooxygenase 2 | Humans | Middle Aged | Synovial Membrane - pathology | Synovial Membrane - drug effects | Arthritis, Rheumatoid - metabolism | Caspases - metabolism | Isoenzymes - metabolism | Interleukin-1 - physiology | Caspase 3 | Interleukin-8 - secretion | DNA Fragmentation - drug effects | Isoenzymes - physiology | Membrane Potentials - drug effects | Interleukin-1 - metabolism | DNA Fragmentation - physiology | Diosgenin - pharmacology | Cells, Cultured | Mitochondria - drug effects | Fibroblasts - pathology | Interleukin-6 - secretion | Dinoprostone - metabolism | Membrane Proteins | Up-Regulation - drug effects | Prostaglandin-Endoperoxide Synthases - metabolism | Fibroblasts - drug effects | Aged | Cell Proliferation - drug effects | Isoenzymes - biosynthesis | Prostaglandin-Endoperoxide Synthases - physiology
Journal Article
Journal Article
Journal Article
Journal of Anatomy, ISSN 0021-8782, 08/2018, Volume 233, Issue 2, pp. 146 - 154
The infrapatellar pad, a fibro‐adipose tissue with peculiar microscopic and mechanical features, is gaining wide attention in the field of rheumatological... 
infrapatellar fat pad | knee plicae | synovial membrane | osteoarthritis | ANATOMY & MORPHOLOGY | PLICAE | PAIN | ARTICULAR-CARTILAGE | DISEASE | SYNOVIOCYTES | KNEE OSTEOARTHRITIS | JOINT | ASSOCIATION | MORPHOLOGY | ADIPOSE-TISSUE | Knee | Cell proliferation | Adipose tissue | Synovial membrane | Cartilage (articular) | Histology | Inflammation
Journal Article
The FEBS Journal, ISSN 1742-464X, 02/2014, Volume 281, Issue 3, pp. 750 - 765
Fibroblast‐like synoviocytes are important mediators of inflammatory joint damage in arthritis through the release of cytokines, but it is unknown whether... 
TNFα | arthritis | SW982 | SNAREs | IL‐6 | Arthritis | IL-6 | RHEUMATOID-ARTHRITIS | CYTOKINE SECRETION | TOXIN-A | TNF alpha | PROTEIN | BOTULINUM-NEUROTOXIN-A | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN SYNOVIOCYTES | SENSORY NEURONS | MEMBRANE-FUSION | JOINT PAIN | CLOSTRIDIAL NEUROTOXINS | Arthritis - metabolism | Membrane Glycoproteins - metabolism | Humans | Qb-SNARE Proteins - metabolism | Qb-SNARE Proteins - genetics | Synovial Membrane - immunology | Protein Transport - drug effects | Synovial Membrane - drug effects | Molecular Targeted Therapy | Exocytosis - drug effects | Membrane Glycoproteins - antagonists & inhibitors | Protein Isoforms - metabolism | Qc-SNARE Proteins - metabolism | RNA Interference | Interleukin-1beta - metabolism | Anti-Inflammatory Agents - therapeutic use | Arthritis - immunology | Qa-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - antagonists & inhibitors | Vesicle-Associated Membrane Protein 3 - genetics | Nerve Tissue Proteins - antagonists & inhibitors | Anti-Inflammatory Agents - pharmacology | Vesicle-Associated Membrane Protein 3 - metabolism | Tumor Necrosis Factor-alpha - secretion | Interleukin-6 - secretion | Nerve Tissue Proteins - genetics | Synovial Membrane - metabolism | Membrane Glycoproteins - genetics | Receptors, Interleukin-1 - metabolism | Nerve Tissue Proteins - metabolism | Synovial Membrane - secretion | Calcium Signaling - drug effects | Qa-SNARE Proteins - metabolism | Arthritis - drug therapy | Cell Line, Tumor | Qc-SNARE Proteins - genetics | Qa-SNARE Proteins - antagonists & inhibitors | Qc-SNARE Proteins - antagonists & inhibitors | RNA, Small Interfering | Qb-SNARE Proteins - antagonists & inhibitors | Protein Isoforms - antagonists & inhibitors | Protein Isoforms - genetics
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 02/2014, Volume 66, Issue 2, pp. 327 - 339
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5205, 2014, Volume 66, Issue 12, pp. 3289 - 3299
Injection of agonistic anti-Fas antibody has been shown to decrease disease symptoms in mouse models of arthritis. Additionally, membrane-bound FasL (mFasL)... 
HUMAN GENOME | SHARED EPITOPE HYPOTHESIS | SUSCEPTIBILITY LOCI | CLASSIFICATION | POPULATIONS | AFRICAN-AMERICANS | RHEUMATOLOGY | INFERENCE | ANCESTRY |