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Immunity, ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 89 - 103
Foxp3 T regulatory (Treg) cells prevent inflammatory disease but the mechanistic basis of suppression is not understood completely. Gene silencing by RNA... 
IN-VITRO | RNA | VESICLES | IFN-GAMMA | RECEPTOR | MECHANISMS | DIFFERENTIATION | RELEASE | DICER | IMMUNOLOGY | EXPRESSION | Biosynthesis | Genetic engineering | MicroRNA | T cells | Analysis | Cell growth | Lymphocytes | Hypoxia | Genomes | Gene expression | Experiments | Immune system
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2010, Volume 185, Issue 1, pp. 302 - 312
Mesenchymal stem cells (MSCs) exert immunomodulatory properties via the inhibition of T cell activation and proliferation. Because of the deleterious role of... 
PROGENITOR CELLS | GROWTH-FACTOR-BETA | TGF-BETA | ROR-GAMMA-T | DENDRITIC CELLS | INTERFERON-GAMMA | SPECIFICITY | NITRIC-OXIDE | IMMUNOLOGY | LYMPHOCYTE-PROLIFERATION | PROSTAGLANDIN-E2 | Cell Communication - immunology | T-Lymphocytes, Regulatory - metabolism | CD18 Antigens - physiology | Coculture Techniques | Humans | Interleukin-17 - physiology | L Cells (Cell Line) | T-Lymphocytes, Regulatory - pathology | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | CD11a Antigen - physiology | Cell Movement - immunology | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | Intercellular Adhesion Molecule-1 - biosynthesis | Inflammation Mediators - metabolism | Receptors, CCR6 - metabolism | T-Lymphocytes, Helper-Inducer - cytology | Inflammation Mediators - physiology | Receptors, CCR6 - physiology | CD11a Antigen - metabolism | Bone Marrow Cells - cytology | Cells, Cultured | Interferon-gamma - physiology | Immunophenotyping | Interleukin-17 - biosynthesis | CD18 Antigens - metabolism | Cell Adhesion - immunology | Cell Differentiation - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Tumor Necrosis Factor-alpha - physiology | Growth Inhibitors - physiology | Ligands | Mice | Mesenchymal Stromal Cells - pathology | Bone Marrow Cells - metabolism
Journal Article
Nature, ISSN 0028-0836, 06/2013, Volume 498, Issue 7452, pp. 42 - 43
Hepworth et al. noted that RORγt-deficient mice had symptoms that were characteristic of immune activation: their spleens were enlarged and contained... 
Immune response | Research | Properties | CD4 lymphocytes | Proteins | Medical research | Immunology | Immune system
Journal Article
Nature Immunology, ISSN 1529-2908, 10/2017, Volume 18, Issue 11, pp. 1249 - 1260
Interleukin 2 (IL-2) promotes Foxp(3+) regulatory T (T-reg) cell responses, but inhibits T follicular helper (T-FH) cell development. However, it is not clear... 
TGF-BETA | HELPER | INFLAMMATION | STAT5 | IL-2 | MICE | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | CUTTING EDGE | ANTIGEN | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Host-Pathogen Interactions - drug effects | Cell Movement - genetics | Host-Pathogen Interactions - immunology | Orthomyxoviridae - immunology | T-Lymphocytes, Regulatory - immunology | Cell Movement - immunology | T-Lymphocytes, Helper-Inducer - drug effects | Interleukin-2 Receptor alpha Subunit - genetics | Forkhead Transcription Factors - metabolism | Interleukin-2 - administration & dosage | T-Lymphocytes, Helper-Inducer - immunology | Proto-Oncogene Proteins c-bcl-6 - metabolism | Transcription Factors - immunology | Interleukin-2 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Orthomyxoviridae Infections - metabolism | Mice, Inbred C57BL | Gene Expression Profiling - methods | Mice, Transgenic | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Mice, Knockout | Proto-Oncogene Proteins c-bcl-6 - genetics | Transcription Factors - metabolism | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Interleukin-2 - pharmacology | Orthomyxoviridae Infections - virology | Orthomyxoviridae - physiology | Orthomyxoviridae Infections - immunology | Positive Regulatory Domain I-Binding Factor 1 | Care and treatment | Immune response | Interleukins | Analysis | Influenza | Research | Diagnosis | Cytokines | Interleukin | Infections | T cell receptors | Lymphocytes T | Follicles | Lymphocytes B | Interleukin 2 | Bcl protein | CD25 antigen | Foxp3 protein | Bcl-6 protein | Immune system
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 08/2019, Volume 106, Issue 2, pp. 369 - 383
The overwhelming body of research on regulatory lymphocytes has focused on CD4+ CD25+ Foxp3+ T cells (regulatory T cells); however, the last 5 years have... 
CD8+ Tregs | ILCregs | γδ‐Tregs | Bregs | regulatory cells | CD8(+) Tregs | CD8(+) TREG CELLS | gamma delta-Tregs | DENDRITIC CELLS | DELTA T-CELLS | ANTIGEN PRESENTATION | IMMUNOLOGY | AUTOIMMUNE ENCEPHALOMYELITIS | CUTTING EDGE | CELL BIOLOGY | B-CELLS | IMMUNE SUPPRESSION | MEDIATED SUPPRESSION | SUPPRESSOR-CELLS | HEMATOLOGY
Journal Article