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NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 10/2012, Volume 11, Issue 10, pp. 763 - 776
The key role of interleukin-17 (IL-17) and T helper 17 (T(H)17) cells in tissue inflammation, autoimmunity and host defence led to the experimental targeting... 
OBSTRUCTIVE PULMONARY-DISEASE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | COLONY-STIMULATING FACTOR | ROR-GAMMA-T | MESSENGER-RNA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RHEUMATOID-ARTHRITIS SYNOVIOCYTES | MUCOSAL HOST-DEFENSE | MAST-CELLS | PHARMACOLOGY & PHARMACY | ANTI-INTERLEUKIN-17 MONOCLONAL-ANTIBODY | HELPER T-CELLS
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 991 - 999
Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are often present at the sites of tissue inflammation in autoimmune diseases, which has led to... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | MULTIPLE-SCLEROSIS | ARYL-HYDROCARBON RECEPTOR | IFN-GAMMA | TRANSFORMING GROWTH-FACTOR-BETA-1 | IL-17-PRODUCING T-CELLS | IMMUNOLOGY | INTERLEUKIN-7 RECEPTOR | CYTOKINE GM-CSF | TH17 CELLS
Journal Article
Nature Immunology, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 991 - 999
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 10/2012, Volume 11, Issue 10, pp. 763 - 776
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 01/2014, Volume 20, Issue 1, pp. 62 - 62
Autoimmune diseases often result from an imbalance between regulatory T (T-reg) cells and interleukin-17 (IL-17)-producing T helper (T(H)17) cells; the origin... 
RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | CELL BIOLOGY | IMMUNE | IMMUNOLOGICAL SELF-TOLERANCE | TNF-ALPHA | DIFFERENTIATION | EXPRESSION | PLASTICITY
Journal Article
NATURE, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 518 - 518
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. Although the underlying genetic basis of this class of... 
OSMOTIC-STRESS | TGF-BETA | MULTIPLE-SCLEROSIS | GENE | THREONINE PROTEIN-KINASE | SGK | MULTIDISCIPLINARY SCIENCES | P38 MAPK | TRANSCRIPTIONAL TARGET | T-CELLS | CYTOKINE GM-CSF
Journal Article
NATURE, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 513 - 517
T(H)17 cells (interleukin-17 (IL-17)-producing helper T cells) are highly proinflammatory cells that are critical for clearing extracellular pathogens and for... 
PATHWAYS | SYSTEM | ACTIVATION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | SERUM | DIFFERENTIATION
Journal Article
ANNUAL REVIEW OF PHYSIOLOGY, ISSN 0066-4278, 2010, Volume 72, pp. 495 - 516
Asthma and chronic obstructive pulmonary disease (COPD) represent two classes of chronic obstructive lung disorders that may share some similar immunologic... 
PHYSIOLOGY | COLONY-STIMULATING FACTOR | BRONCHIAL EPITHELIAL-CELLS | allergy | ALLERGIC AIRWAY INFLAMMATION | HELPER T-CELLS | HYPER-IGE SYNDROME | OBSTRUCTIVE PULMONARY-DISEASE | GROWTH-FACTOR-BETA | inflammation | IL-17 | MYCOBACTERIUM-TUBERCULOSIS INFECTION | SMOOTH-MUSCLE-CELLS | NF-KAPPA-B
Journal Article
NATURE, ISSN 0028-0836, 06/2014, Volume 510, Issue 7503, pp. 152 - 152
T-helper-17 (T(H)17) cells have critical roles in mucosal defence and in autoimmune disease pathogenesis(1-3). They are most abundant in the small intestine... 
MULTIDISCIPLINARY SCIENCES | MICROBIOTA | INDUCTION | DIFFERENTIATION | IDENTIFICATION | MATURATION | TH17 | EXPRESSION | SEGMENTED FILAMENTOUS BACTERIA | T-CELLS | PREDICTION
Journal Article
NATURE, ISSN 0028-0836, 07/2011, Volume 475, Issue 7357, pp. 514 - U114
Interleukin (IL)-17-producing T helper cells (T(H)17) are a recently identified CD4(+) T cell subset distinct from T helper type 1 (T(H)1) and T helper type 2... 
GROWTH-FACTOR-BETA | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | MULTIDISCIPLINARY SCIENCES | MONOCLONAL-ANTIBODY | MICE | DIFFERENTIATION | INTERLEUKIN-10 | T-H-17 CELLS | T-CELLS | TH17 CELLS
Journal Article
NATURE REVIEWS IMMUNOLOGY, ISSN 1474-1733, 04/2019, Volume 19, Issue 4, pp. 200 - 201
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 04/2019, Volume 19, Issue 4, pp. 200 - 201
Journal Article
Journal Article
Journal Article
MOLECULAR IMMUNOLOGY, ISSN 0161-5890, 05/2019, Volume 109, pp. 81 - 87
IL-17-producing T(H)17 cells have been associated with autoimmune diseases such as multiple sclerosis (MS), psoriasis, Crohn's disease, and ulcerative colitis... 
EFFECTOR T-CELLS | ROR-GAMMA-T | BIOCHEMISTRY & MOLECULAR BIOLOGY | HELPER 17 | IMMUNOLOGY | BALANCE | CXC CHEMOKINE RECEPTOR-5 | HIF1 alpha Glycolysis | T(H)17 | mTOR | GENERATION | DIFFERENTIATION | TRANSCRIPTION FACTOR | EXPRESSION | Fatty acid synthesis | TH17 CELLS
Journal Article
NATURE, ISSN 0028-0836, 04/2012, Volume 484, Issue 7395, pp. 514 - U139
IL-17-producing CD4(+) T helper cells (T(H)17) have been extensively investigated in mouse models of autoimmunity(1). However, the requirements for... 
HYPER-IGE SYNDROME | GROWTH-FACTOR-BETA | TGF-BETA | MEMORY | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | HELPER-CELLS | CD4(+) T-CELLS | DIFFERENTIATION | TH17 CELLS | PROSTAGLANDIN-E2
Journal Article
Molecular Immunology, ISSN 0161-5890, 05/2019, Volume 109, pp. 81 - 87
IL-17-producing T 17 cells have been associated with autoimmune diseases such as multiple sclerosis (MS), psoriasis, Crohn's disease, and ulcerative colitis... 
Glycolysis | mTOR | T | HIF1α | 17 | Fatty acid synthesis | Animals | Signal Transduction | Th17 Cells - metabolism | Humans | Th17 Cells - cytology | Cell Differentiation | Lipogenesis
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 04/2013, Volume 14, Issue 4, pp. 372 - 379
Intestinal Peyer's patches are essential lymphoid organs for the generation of T cell-dependent immunoglobulin A (IgA) for gut homeostasis. Through the use of... 
HETEROGENEITY | ROR-GAMMA-T | GUT | RECEPTOR | GENERATION | DIFFERENTIATION | IMMUNOLOGY | SEGMENTED FILAMENTOUS BACTERIA | FOLLICULAR HELPER-CELLS | CENTER B-CELL | TH17 CELLS
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2008, Volume 181, Issue 6, pp. 4089 - 4097
Steroid-resistant asthma comprises an important source of morbidity in patient populations. T(H)17 cells represent a distinct population of CD4(+) Th cells... 
HUMAN NEUTROPHILS | COLONY-STIMULATING FACTOR | DENDRITIC CELLS | INTERLEUKIN-17 | NON-EOSINOPHILIC ASTHMA | ALLERGIC-ASTHMA | MAST-CELLS | IMMUNOLOGY | IL-17 PRODUCTION | T-CELLS | TH17 CELLS
Journal Article
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