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NATURE IMMUNOLOGY, ISSN 1529-2908, 10/2015, Volume 16, Issue 10, pp. 1051 - 1051
Type 2 helper T cells (T(H)2 cells) produce interleukin 13 (IL-13) when stimulated by papain or house dust mite extract (HDM) and induce eosinophilic... 
HYGIENE HYPOTHESIS | CYTOKINE PRODUCTION | IL-1 FAMILY | CHRONIC HELMINTH INFECTIONS | IMMUNE-RESPONSES | DISEASE | AIRWAY INFLAMMATION | INTERLEUKIN-13 | ASTHMA | IMMUNOLOGY | LYMPHOID-CELLS
Journal Article
Nature Immunology, ISSN 1529-2908, 09/2015, Volume 16, Issue 10, pp. 1051 - 1059
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 04/2014, Volume 133, Issue 4, pp. 1184 - 1184
Journal Article
NATURE REVIEWS IMMUNOLOGY, ISSN 1474-1733, 12/2010, Volume 10, Issue 12, pp. 838 - 848
Journal Article
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 08/2008, Volume 20, Issue 8, pp. 1019 - 1030
IL-33 is an IL-1 family member recently identified as the ligand for T1/ST2 (ST2), a member of the IL-1 receptor family. ST2 is stably expressed on mast cells... 
NK cells | T(h)1/T(h)2 cells | MAST-CELLS | EFFECTOR FUNCTION | INNATE IMMUNE-RESPONSE | CD4(+) T-CELLS | IMMUNOLOGY | RECEPTOR ACCESSORY PROTEIN | inflammation | HUMAN IGE SYNTHESIS | cytokines | SOLUBLE ST2 PROTEIN | HUMAN TH2 CELLS | T1/ST2 EXPRESSION | ACUTE EXACERBATION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 11/2009, Volume 106, Issue 44, pp. 18704 - 18709
Allergic asthma is an inflammatory disease of the lung characterized by abnormal T helper-2 (T(H)2) lymphocyte responses to inhaled antigens. The molecular... 
HYPERREACTIVITY | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL ASTHMA | T(H)2 cytokines | asthma | PLASMA-CELLS | inflammation | INHALED ANTIGEN | IMMUNE-RESPONSES | IN-VIVO | TOLL-LIKE RECEPTORS | microRNA | animal model | LINKING INNATE | EXPRESSION
Journal Article
MUCOSAL IMMUNOLOGY, ISSN 1933-0219, 11/2016, Volume 9, Issue 6, pp. 1407 - 1417
Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-4 (IL-4)-directed type 2 helper (TH2) differentiation of CD4(+) T... 
HELMINTH EXPULSION | ALTERNATIVELY ACTIVATED MACROPHAGES | CYTOKINE PRODUCTION | TRANSCRIPTION FACTOR GATA3 | MAST-CELLS | IN-VIVO | CD4(+) T-CELLS | TYPE-2 IMMUNITY | INNATE LYMPHOID-CELLS | IMMUNOLOGY | LUNG INFLAMMATION
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 05/2016, Volume 137, Issue 5, pp. 1514 - 1524
Background: Chronic rhinosinusitis with nasal polyposis (CRSwNP) in Western countries is characterized by eosinophilia, IgE production, and T(H)2 cytokine... 
T(H)2 cells | IL-17RB | AIRWAY INFLAMMATION | IL-25 | T-cell phenotype | INNATE LYMPHOID-CELLS | IMMUNOLOGY | IL-33 | CHRONIC RHINOSINUSITIS | CUTTING EDGE | ST2 | microarray | CYTOKINE PRODUCTION | Chronic rhinosinusitis with nasal polyps | ALLERGY | T-cell receptor V beta repertoire | HOST-DEFENSE | nasal mucosa | TYPE-2 IMMUNITY | HUMAN TH2 CELLS | T(H)17 cells | T-CELLS | TH17 CELLS
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 04/2016, Volume 137, Issue 4, pp. 1216 - 1216
Background: Food-mediated allergic reactions have emerged as a major health problem. The underlying mechanisms that promote uncontrolled type 2 immune... 
MAST-CELLS | IL-25 | CYTOKINE | IL-13 | IMMUNOLOGY | food allergy | THYMIC STROMAL LYMPHOPOIETIN | CD4(+) T(H)2 cells | type 2 innate lymphoid cells | ALLERGY | IMMUNE-RESPONSES | INFLAMMATION | INTERLEUKIN-25 | EXPRESSION | ANAPHYLAXIS | T-CELLS | ANTIGEN
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 03/2009, Volume 123, Issue 3, pp. 619 - 625
Background: Histamine influences T-cell reactions via histamine receptors I and 2. The histamine receptor 4 (H4R) is the most recently identified histamine... 
ACTIVATION | ANTIHISTAMINES | DENDRITIC CELLS | PRURITUS | AIRWAY INFLAMMATION | IMMUNOLOGY | T cells | IL-31 | SCRATCHING BEHAVIOR | Histamine | ATOPIC-DERMATITIS | ALLERGY | MICE | H-4 receptor | T-CELLS
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 08/2017, Volume 9, Issue 401
A new proinflammatory subtype of antigen-specific T-H 2 cell that expresses CD161 emerges as the pathogenic cell type in allergic disease and is deleted during... 
MEDICINE, RESEARCH & EXPERIMENTAL | SUBPOPULATION | DEFINES | CELL BIOLOGY
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 02/2015, Volume 6
Lymphatic vessels (LVs) are critical for immune surveillance and involved in the pathogenesis of diverse diseases. LV density is increased during inflammation;... 
SYSTEM | INTERLEUKIN-4 | ANGIOGENESIS | ENDOTHELIUM | VASCULATURE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | LYMPHANGIOGENESIS | RECEPTOR | DIFFERENTIATION
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 01/2017, Volume 139, Issue 1, pp. 246 - 246
Background: Although the prominent role of T(H)2 cells in type 2 immune responses is well established, the newly identified type 2 innate lymphoid cells... 
LUNG | Diesel exhaust particles | house dust mite | asthma | IL-25 | IMMUNOLOGY | IL-33 | type 2 innate lymphoid cell | ALLERGY | SENSITIZATION | INFLAMMATION | T(H)2 response | EXPRESSION | ASSOCIATION | T-CELLS
Journal Article
Science translational medicine, ISSN 1946-6234, 08/2017, Volume 9, Issue 401, p. eaao0392
A new proinflammatory subtype of antigen-specific T 2 cell that expresses CD161 emerges as the pathogenic cell type in allergic disease and is deleted during... 
Hypersensitivity - immunology | Models, Immunological | Clinical Trials as Topic | Th2 Cells - immunology | Humans
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 02/2016, Volume 137, Issue 2, pp. 545 - 558
Background: Regulatory dendritic cell (DC) markers, such as C1Q, are upregulated in PBMCs of patients with grass pollen allergy exhibiting clinical benefit... 
MECHANISMS | INDUCTION | IMMUNOLOGY | biomarker | B-CELLS | GRASS-POLLEN IMMUNOTHERAPY | ALLERGY | YELLOW-FEVER VACCINE | monocyte | sublingual immunotherapy | ANTIBODY-RESPONSES | EXPRESSION | dendritic cell | Allergen | IMMUNOGLOBULIN-E | TH2
Journal Article
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 08/2018, Volume 142, Issue 2, pp. 569 - 569
Background: The mechanisms that regulate maintenance of persistent T(H)2 cells and potentiate allergic inflammation are not well understood. Objective: The... 
SERPIN | memory | T(H)2 cells | AIRWAY INFLAMMATION | apoptosis | grass pollen allergy | CD4(+) T-CELLS | INNATE LYMPHOID-CELLS | MEDIATED APOPTOSIS | IMMUNOLOGY | MEMORY CELLS | ATOPIC-DERMATITIS | TH2 MEMORY | ALLERGY | CATHEPSIN-G | CARCINOMA ANTIGEN-2
Journal Article
ELIFE, ISSN 2050-084X, 02/2016, Volume 5
A polymorphism in the autophagy gene Atg1611 is associated with susceptibility to inflammatory bowel disease (IBD); however, it remains unclear how autophagy... 
IMPAIRED AUTOPHAGY | IBD GENETICS | CROHN-DISEASE | PROTEIN | BIOLOGY | FATTY-ACID-METABOLISM | DEGRADATION | VARIANT | GENOME-WIDE ASSOCIATION | BOWEL-DISEASE | LYMPHOCYTES
Journal Article
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