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CELL METABOLISM, ISSN 1550-4131, 02/2010, Volume 11, Issue 2, pp. 136 - 146
Aging increases oxidative stress and osteoblast apoptosis and decreases bone mass, whereas forkhead box O (FoxO) transcription factors defend against oxidative... 
CRUCIAL ROLE | FORKHEAD TRANSCRIPTION FACTOR | LIFE-SPAN | DEFICIENCY BONE LOSS | ENDOCRINOLOGY & METABOLISM | T-CELL-FACTOR | KAPPA-B | BETA-CATENIN | SEX STEROIDS | OSTEOCLAST DIFFERENTIATION | PROTEIN-KINASE B | CELL BIOLOGY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2004, Volume 101, Issue 34, pp. 12682 - 12687
Inherited and somatic mutations in the adenomatous polyposis coli occur in most colon cancers, leading to activation of β-catenin-responsive genes. To identify... 
T lymphocytes | Molecules | Biological Sciences | Epithelial cells | HCT116 cells | Genes | Cell lines | Colorectal cancer | Small interfering RNA | Antibodies | Cyclins | Coactivators | Wnt pathway | T cell factor | TARGET | APOPTOSIS | COMPLEX | GENE | CYCLIN D1 | COLORECTAL-CANCER | SURVIVIN | INTERACTS | MULTIDISCIPLINARY SCIENCES | EXPRESSION | COLON-CARCINOMA | Proteins | Medical research | Mutation | Cells | coactivators
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 36, pp. 14178 - 14189
Variants in the transcription factor-7-like 2 (TCF7L2/TCF4) gene, involved in Wnt signaling, are associated with type 2 diabetes. Loss of Tcf7l2 selectively... 
TCF7L2 | pancreatic islet | liver kinase B1 (LKB1) | pancreatic cell | PEUTZ-JEGHERS-SYNDROME | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELLS | cell growth | RISK | T-cell factor (TCF) | insulin secretion | LKB1 | IDENTITY | GLUCOSE-HOMEOSTASIS | MASS | EXPANSION | MICE | EXPRESSION
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 45, pp. 34621 - 34631
The formation of a β-catenin·TCF4 complex in the nucleus of cells is well known as a prerequisite for the transcription of Wnt target genes. Although many... 
T-cell Factor (TCF) | Signal Transduction | p15RS | β-Catenin | Tumor | Wnt Pathway | Cell Biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 14, pp. 5335 - 5344
The Wnt/-catenin pathway is essential for embryonic development and homeostasis, but excessive activation of this pathway is frequently observed in various... 
APOPTOSIS | small molecule | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | FEVERFEW | protein synthesis | OSTEOSARCOMA CELLS | T-cell factor (TCF) | BETA-CATENIN | CANCER | STEM | Wnt signaling | inhibitor | PATHWAY | GENOME-WIDE | NF-KAPPA-B
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2004, Volume 24, Issue 30, pp. 6791 - 6798
Journal Article
Journal of Cell Science, ISSN 0021-9533, 04/2006, Volume 119, Issue 7, pp. 1283 - 1296
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2006, Volume 103, Issue 49, pp. 18580 - 18585
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2016, Volume 126, Issue 5, pp. 1745 - 1758
Journal Article
BMC Cancer, ISSN 1471-2407, 11/2013, Volume 13, Issue 1, pp. 537 - 537
Background: Triple Negative subset of (TN) Breast Cancers (BC), a close associate of the basal-like subtype (with limited discordance) is an aggressive form of... 
Breast cancer | Microarray | Wnt | FFPE | Triple negative | GENE-EXPRESSION SIGNATURE | ANDROGEN RECEPTOR | REGULATES EXPRESSION | SUBTYPES | T-CELL-FACTOR | BETA-CATENIN | MESENCHYMAL TRANSITION | ONCOLOGY | PATHWAY | COLORECTAL-CANCER | BASAL | RNA, Small Interfering - genetics | Cell Proliferation | Prognosis | Follow-Up Studies | Oligonucleotide Array Sequence Analysis | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Bone Neoplasms - secondary | Gene Expression Profiling | Wnt Proteins - metabolism | Brain Neoplasms - metabolism | Immunoenzyme Techniques | Bone Neoplasms - metabolism | Neoplasm Recurrence, Local - pathology | Paraffin Embedding | Brain Neoplasms - secondary | Wnt Proteins - genetics | Lung Neoplasms - secondary | Triple Negative Breast Neoplasms - pathology | Biomarkers, Tumor - metabolism | Female | Bone Neoplasms - genetics | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Lung Neoplasms - genetics | Neoplasm Recurrence, Local - metabolism | Signal Transduction | RNA, Messenger - genetics | Brain Neoplasms - genetics | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Triple Negative Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - metabolism | beta Catenin - antagonists & inhibitors | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Neoplasm Staging | Cell Movement | Cohort Studies | Research | Metastasis | Biological markers | Analysis | Oncology, Experimental | Cancer | Index Medicus
Journal Article
ACTA PHYSIOLOGICA, ISSN 1748-1708, 01/2012, Volume 204, Issue 1, pp. 74 - 109
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 52, pp. 44326 - 44335
Endogenous glucocorticoids (GCs) and inflammatory cytokines contribute to the age-associated loss of bone mass and strength, but the molecular mechanisms... 
TRANSCRIPTIONAL ACTIVITY | REACTIVE OXYGEN | BONE-MINERAL DENSITY | PROTEASOMAL DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FORKHEAD-BOX-O | GENE-EXPRESSION | EXTENDS LIFE-SPAN | T-CELL-FACTOR | BETA-CATENIN | NF-KAPPA-B | Tumor Necrosis Factor-alpha - metabolism | Shc Signaling Adaptor Proteins - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Oxidative Stress - physiology | Tumor Necrosis Factor-alpha - genetics | Wnt Signaling Pathway - physiology | Male | Wnt Proteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Dexamethasone - pharmacology | MAP Kinase Kinase 4 - metabolism | Wnt Proteins - genetics | Forkhead Transcription Factors - metabolism | Female | Osteoblasts - cytology | Proto-Oncogene Proteins c-akt - metabolism | Cell Differentiation - physiology | Forkhead Transcription Factors - genetics | Prednisolone - pharmacology | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Animals | Shc Signaling Adaptor Proteins - genetics | Src Homology 2 Domain-Containing, Transforming Protein 1 | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Glucocorticoids - pharmacology | MAP Kinase Kinase 4 - genetics | Cell Proliferation - drug effects | Mice | Apoptosis - physiology | Oxidative Stress - drug effects | Osteoblasts - metabolism | Index Medicus | Wnt Signaling | FoxO | Glucocorticoids | Oxidative Stress | Tumor Necrosis Factor (TNF) | Osteoblasts | Cell Biology
Journal Article
Aging Cell, ISSN 1474-9718, 04/2010, Volume 9, Issue 2, pp. 147 - 161
Journal Article
Translational Psychiatry, ISSN 2158-3188, 12/2018, Volume 8, Issue 1, pp. 232 - 11
Susceptible genetic polymorphisms and altered expression levels of protein kinase C (PKC)-encoding genes suggest overactivation of PKC in autism spectrum... 
PATHWAY | PSYCHIATRY | INFLAMMATION | DYSREGULATION | NEUROGENESIS | DYSFUNCTION | AUTISM SPECTRUM DISORDERS | T CELL-FACTOR | LARVAL ZEBRAFISH | IDENTIFICATION | BRAIN | Kinases | Index Medicus
Journal Article