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Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 482 - 485
Despite antiretroviral therapy, proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to curing the infection(1).... 
CELLS | ACTIVATION | SUBEROYLANILIDE HYDROXAMIC ACID | MULTIDISCIPLINARY SCIENCES | IN-VIVO | VALPROIC ACID | INFECTION | HISTONE DEACETYLASE INHIBITORS | TYPE-1 | EXPRESSION | PCR | Gene Expression Regulation, Viral - drug effects | Humans | Hydroxamic Acids - adverse effects | Histone Deacetylase Inhibitors - administration & dosage | RNA, Viral - blood | Virus Latency - drug effects | Proviruses - drug effects | HIV-1 - growth & development | Proviruses - genetics | Hydroxamic Acids - administration & dosage | Anti-HIV Agents - therapeutic use | CD4-Positive T-Lymphocytes - virology | Hydroxamic Acids - pharmacology | Biomarkers - metabolism | HIV Infections - blood | Risk Assessment | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | RNA, Viral - biosynthesis | CD4-Positive T-Lymphocytes - metabolism | Viremia - drug therapy | HIV-1 - genetics | Proviruses - growth & development | Histones - drug effects | Up-Regulation - drug effects | Acetylation - drug effects | Viremia - virology | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Histones - metabolism | CD4-Positive T-Lymphocytes - drug effects | Histone Deacetylase Inhibitors - adverse effects | Physiological aspects | Antiviral agents | HIV patients | Health aspects | Vorinostat | Antiretroviral drugs | Plasma | Cell culture | Lymphocytes | Human immunodeficiency virus--HIV | Genomes | Drug therapy | Drug dosages | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 539, Issue 7629, pp. 443 - 447
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3272 - 3291
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7693, pp. 538 - 543
Most patients with colorectal cancer die as a result of the disease spreading to other organs. However, no prevalent mutations have been associated with... 
STEM-CELLS | GENE | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MOUSE | LEADS | RECEPTOR | MICE | GROWTH-FACTOR | TUMORIGENESIS | EXPRESSION | Intestines - drug effects | Colonic Neoplasms - genetics | Intestinal Mucosa - metabolism | Colonic Neoplasms - drug therapy | Humans | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Stem Cells - metabolism | Th1 Cells - immunology | T-Lymphocytes, Cytotoxic - drug effects | Neoplasm Metastasis - drug therapy | Neoplasm Metastasis - immunology | Colonic Neoplasms - immunology | Immunotherapy | Transforming Growth Factor beta - antagonists & inhibitors | Female | Liver Neoplasms - secondary | Disease Models, Animal | T-Lymphocytes, Cytotoxic - immunology | Transforming Growth Factor beta - immunology | Tumor Microenvironment - drug effects | Th1 Cells - drug effects | Intestines - pathology | Liver Neoplasms - drug therapy | Liver Neoplasms - immunology | Drug Synergism | Tumor Microenvironment - immunology | Neoplasm Metastasis - genetics | Animals | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Colonic Neoplasms - pathology | Alleles | Immune Evasion - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Mice | Mutation | T-Lymphocytes, Cytotoxic - cytology | PD-1 protein | Liver | Colorectal carcinoma | Colorectal cancer | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Metastasis | Metastases | Colon cancer | Intestine | Lymphocytes | Genetic analysis | Fibroblasts | Colon | Inhibition | Growth factors | Phenotypes | Data analysis | Liver diseases | Microsatellites | Organs | Gene expression | Patients | Signaling | Immune checkpoint | PD-L1 protein | Stem cells | Tumors | Cancer | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 7, pp. 1192 - 1202
Journal Article
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 11, pp. 1327 - 1333
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2016, Volume 22, Issue 9, pp. 991 - 993
Journal Article
Cell Metabolism, ISSN 1550-4131, 11/2016, Volume 24, Issue 5, pp. 657 - 671
Journal Article
Nature, ISSN 0028-0836, 08/2017, Volume 548, Issue 7668, pp. 471 - 475
Cyclin-dependent kinases 4 and 6 (CDK4/6) are fundamental drivers of the cell cycle and are required for the initiation and progression of various... 
BREAST-CANCER | CELLS | METHYLATION | MULTIDISCIPLINARY SCIENCES | SENESCENCE | EXPRESSION | REQUIREMENT | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Viruses - genetics | Breast Neoplasms - immunology | Humans | Transcriptome | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Regulatory - cytology | Female | Biological Mimicry - drug effects | Phosphorylation - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Disease Models, Animal | Viruses - drug effects | Viruses - immunology | Antigen Presentation - immunology | Breast Neoplasms - drug therapy | T-Lymphocytes, Regulatory - drug effects | Animals | Breast Neoplasms - genetics | Repressor Proteins - biosynthesis | Signal Transduction - drug effects | Breast Neoplasms - pathology | Cell Cycle Checkpoints - drug effects | Protein Kinase Inhibitors - therapeutic use | RNA, Double-Stranded - genetics | Cell Line, Tumor | Interferons - metabolism | Antigen Presentation - drug effects | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Oncology, Experimental | Cancer cells | Physiological aspects | Research | Protein kinases | Immunity | Cyclins | Cancer | Cell proliferation | Flow cytometry | Animal models | Phosphorylation | Senescence | Peptides | Genomics | Immune clearance | Cytotoxicity | Lymphocytes T | Genomes | Kinases | Cancer therapies | Cyclin-dependent kinase 4 | E2F protein | Breast carcinoma | Cell growth | Lymphocytes | New combinations | Cell cycle | Inhibition | Deoxyribonucleic acid--DNA | Antigen presentation | Medical research | Immune response | Immunoregulation | Intracellular levels | Double-stranded RNA | Breast cancer | Pharmacology | Gene expression | Ribonucleic acid--RNA | Immune systems | Inhibitors | Immune checkpoint | Immunogenicity | Breast | DNA methyltransferase | Interferon | Retinoblastoma | Tumors | Apoptosis | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 9, pp. 1695 - 1710
Treatment with monoclonal antibody specific for cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), an inhibitory receptor expressed by T lymphocytes, has... 
EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | CTLA-4 BLOCKADE | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | CANCER-PATIENTS | IN-VIVO | COMBINATION IMMUNOTHERAPY | MONOCLONAL-ANTIBODY | IMMUNOLOGY | LARGE ESTABLISHED MELANOMA | GAMMA-RIV | ANTITUMOR-ACTIVITY | Fas Ligand Protein - metabolism | Lymph Nodes - pathology | Antibodies, Blocking - pharmacology | Lymphocyte Depletion | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Receptors, IgG - metabolism | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Melanoma - prevention & control | Lymph Nodes - drug effects | Cell Membrane - metabolism | Clone Cells | Cell Membrane - drug effects | Tumor Microenvironment - drug effects | Phagocytes - drug effects | Mice, Inbred C57BL | Treatment Outcome | Lymph Nodes - immunology | Lymphocytes, Tumor-Infiltrating - drug effects | Melanoma - pathology | Phagocytes - immunology | TNF-Related Apoptosis-Inducing Ligand - metabolism | Tumor Microenvironment - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocytes, Tumor-Infiltrating - pathology | Signal Transduction - drug effects | Melanoma - immunology | CD8-Positive T-Lymphocytes - drug effects | Antibodies, Blocking - therapeutic use | Lymphocyte Count | Mice | CD11b Antigen - metabolism | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Melanoma - therapy | CD4 Antigens - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
Journal Article