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1. Full Text Expansion of HIV-specific T follicular helper cells in chronic HIV infection
by Lindqvist, Madelene and Van Lunzen, Jan and Soghoian, Damien Z and Kuhl, Bjorn D and Ranasinghe, Srinika and Kranias, Gregory and Flanders, Michael D and Cutler, Samuel and Yudanin, Naomi and Muller, Matthias I and Davis, Isaiah and Farber, Donna and Hartjen, Philip and Haag, Friedrich and Alter, Galit and Zur Wiesch, Julian Schulze and Streeck, Hendrik
The Journal of clinical investigation, ISSN 0021-9738, 09/2012, Volume 122, Issue 9, pp. 3271 - 3280
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cell Proliferation | Lymph Nodes - pathology | Immunoglobulin G - blood | Humans | Case-Control Studies | T-Lymphocytes, Helper-Inducer - virology | DNA-Binding Proteins - metabolism | HIV Infections - immunology | HIV-1 - physiology | HIV Infections - pathology | T-Lymphocytes, Helper-Inducer - immunology | B-Lymphocytes - metabolism | Anti-Retroviral Agents - therapeutic use | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Anti-Retroviral Agents - pharmacology | Cells, Cultured | Lymph Nodes - immunology | Host-Pathogen Interactions | T-Lymphocytes, Helper-Inducer - physiology | HIV-1 - immunology | Viremia - virology | HIV Infections - drug therapy | Chronic Disease | Interleukins - secretion | Proto-Oncogene Proteins c-bcl-6 | Index Medicus | Abridged Index Medicus
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2. Full Text PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals
by Banga, Riddhima and Procopio, Francesco Andrea and Noto, Alessandra and Pollakis, Georgios and Cavassini, Matthias and Ohmiti, Khalid and Corpataux, Jean-Marc and De Leval, Laurence and Pantaleo, Giuseppe and Perreau, Matthieu
Nature medicine, ISSN 1078-8956, 07/2016, Volume 22, Issue 7, pp. 754 - 761
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - cytology | Humans | Middle Aged | CD4-Positive T-Lymphocytes - metabolism | Programmed Cell Death 1 Receptor - metabolism | Male | Lymph Nodes - virology | HIV-1 - genetics | Lymph Nodes - cytology | Case-Control Studies | T-Lymphocytes, Helper-Inducer - virology | Antiretroviral Therapy, Highly Active | HIV-1 - physiology | Virus Replication | T-Lymphocytes, Helper-Inducer - cytology | Adult | Female | HIV Infections - drug therapy | RNA, Viral - metabolism | CD4-Positive T-Lymphocytes - virology | Cellular biology | Drug therapy | Human immunodeficiency virus--HIV | Index Medicus
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3. Full Text Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses
by Locci, Michela and Havenar-Daughton, Colin and Landais, Elise and Wu, Jennifer and Kroenke, Mark A and Arlehamn, Cecilia L and Su, Laura F and Cubas, Rafael and Davis, Mark M and Sette, Alessandro and Haddad, Elias K and Poignard, Pascal and Crotty, Shane and International AIDS Vaccine Initiative Protocol C Principal Investigators and Int AIDS Vaccine Initiative Protoc
Immunity (Cambridge, Mass.), ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 758 - 769
Life Sciences & Biomedicine | Immunology | Science & Technology | Germinal Center - immunology | Humans | Molecular Sequence Data | Gene Expression Profiling | T-Lymphocytes, Helper-Inducer - virology | HIV Infections - immunology | HIV Infections - pathology | Immunity, Humoral | T-Lymphocytes, Helper-Inducer - immunology | B-Lymphocytes - virology | HIV Antibodies - biosynthesis | T-Lymphocytes, Helper-Inducer - pathology | B-Lymphocytes - pathology | Amino Acid Sequence | Gene Expression | Receptors, CXCR5 - genetics | Signal Transduction | HIV Infections - virology | Germinal Center - pathology | Receptors, CXCR5 - immunology | HIV-1 - immunology | B-Lymphocytes - immunology | Antibodies, Neutralizing - biosynthesis | Germinal Center - virology | Receptors, CXCR3 - genetics | Receptors, CXCR3 - immunology | Immunologic Memory | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Antigens | Hypotheses | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Infections | Vaccines | Mutation | Gene expression | Viral infections | Immune system | Index Medicus
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4. Full Text Circulating Precursor CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure
by He, Jing and Tsai, Louis M and Leong, Yew Ann and Hu, Xin and Ma, Cindy S and Chevalier, Nina and Sun, Xiaolin and Vandenberg, Kirsten and Rockman, Steve and Ding, Yan and Zhu, Lei and Wei, Wei and Wang, Changqi and Karnowski, Alexander and Belz, Gabrielle T and Ghali, Joanna R and Cook, Matthew C and Riminton, D. Sean and Veillette, Andre and Schwartzberg, Pamela L and Mackay, Fabienne and Brink, Robert and Tangye, Stuart G and Vinuesa, Carola G and Mackay, Charles R and Li, Zhanguo and Yu, Di
Immunity (Cambridge, Mass.), ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 770 - 781
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CXCR - immunology | Germinal Center - immunology | Humans | T-Lymphocytes, Helper-Inducer - virology | Immunity, Humoral | T-Lymphocytes, Helper-Inducer - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | Antibodies - immunology | B-Lymphocytes - virology | Cell Differentiation | T-Lymphocytes, Helper-Inducer - pathology | B-Lymphocytes - pathology | Inducible T-Cell Co-Stimulator Protein - immunology | Gene Expression | DNA-Binding Proteins - immunology | Receptors, CXCR5 - genetics | Receptors, CXCR - genetics | Immunophenotyping | Germinal Center - pathology | DNA-Binding Proteins - genetics | Receptors, CXCR5 - immunology | Animals | B-Lymphocytes - immunology | Germinal Center - virology | Antigens - immunology | Immunologic Memory | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Proto-Oncogene Proteins c-bcl-6 | Index Medicus
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5. Full Text The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
by Ray, John P and Staron, Matthew M and Shyer, Justin A and Ho, Ping-Chih and Marshall, Heather D and Gray, Simon M and Laidlaw, Brian J and Araki, Koichi and Ahmed, Rafi and Kaech, Susan M and Craft, Joe
Immunity (Cambridge, Mass.), ISSN 1074-7613, 10/2015, Volume 43, Issue 4, pp. 690 - 702
Life Sciences & Biomedicine | Immunology | Science & Technology | Lymphocytic choriomeningitis virus - immunology | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | NFATC Transcription Factors - physiology | Th1 Cells - immunology | Interleukin-2 Receptor alpha Subunit - physiology | Mechanistic Target of Rapamycin Complex 1 | T-Lymphocytes, Helper-Inducer - virology | Th1 Cells - metabolism | Interleukin-2 - physiology | T-Lymphocytes, Helper-Inducer - immunology | Cell Division | T-Lymphocytes, Helper-Inducer - cytology | TOR Serine-Threonine Kinases - physiology | Calcium Signaling | Specific Pathogen-Free Organisms | T-Lymphocytes, Helper-Inducer - metabolism | Mice, Inbred C57BL | Oxygen Consumption | Transcription Factors - biosynthesis | Proto-Oncogene Proteins c-akt - physiology | Transcription Factors - genetics | Multiprotein Complexes - physiology | Animals | Cell Cycle | T-Lymphocyte Subsets - metabolism | Glucose - metabolism | Glycolysis | Signal Transduction - physiology | Th1 Cells - cytology | Enzyme Activation | Apoptosis | Positive Regulatory Domain I-Binding Factor 1 | Virus diseases | Physiological aspects | Glucose metabolism | Interleukins | T cells | Proteins | Flow cytometry | Scholarships & fellowships | Transcription factors | Cytokines | Lymphocytes | Cell cycle | Kinases | Metabolism | Gene expression | Viral infections | Index Medicus
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6. Full Text Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease
by David Favre and Jeff Mold and Peter W. Hunt and Bittoo Kanwar and P’ng Loke and Lillian Seu and Jason D. Barbour and Margaret M. Lowe and Anura Jayawardene and Francesca Aweeka and Yong Huang and Daniel C. Douek and Jason M. Brenchley and Jeffrey N. Martin and Frederick M. Hecht and Steven G. Deeks and Joseph M. McCune
Science Translational Medicine, ISSN 1946-6234, 05/2010, Volume 2, Issue 32, pp. 32ra36 - ra36
Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | T-Lymphocytes, Regulatory - metabolism | Up-Regulation | Prospective Studies | Colon, Sigmoid - immunology | Dendritic Cells - immunology | Humans | Interleukin-17 - immunology | HIV Infections - enzymology | Lipopolysaccharides - immunology | Rectum - virology | Tryptophan - metabolism | Viral Load | T-Lymphocytes, Helper-Inducer - virology | T-Lymphocytes, Regulatory - immunology | Lymph Nodes - enzymology | HIV Infections - immunology | CD4-CD8 Ratio | Colon, Sigmoid - virology | Time Factors | T-Lymphocytes, Helper-Inducer - immunology | Colon, Sigmoid - enzymology | Kynurenine - metabolism | Dendritic Cells - virology | Inflammation Mediators - immunology | T-Lymphocytes, Helper-Inducer - metabolism | HIV Seropositivity | HIV Infections - virology | Cells, Cultured | Inflammation - virology | CD4 Lymphocyte Count | Inflammation - immunology | Lymph Nodes - virology | 3-Hydroxyanthranilic Acid - metabolism | Lymph Nodes - immunology | Rectum - immunology | Disease Progression | Rectum - enzymology | Biopsy | Dendritic Cells - enzymology | Interferon-gamma - immunology | HIV Infections - drug therapy | Inflammation - enzymology | T-Lymphocytes, Regulatory - virology | Index Medicus
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7. Full Text Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4⁺ T Cells
by John J. O'Shea and William E. Paul
Science (American Association for the Advancement of Science), ISSN 0036-8075, 2/2010, Volume 327, Issue 5969, pp. 1098 - 1102
T lymphocytes | Beta cells | Transcription factors | Cytokines | Cell lines | Stem cells | Epigenetics | Review | Pluripotent stem cells | Cellular differentiation | Cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Microbiology | Virology | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Helper-Inducer - metabolism | T-Lymphocyte Subsets - cytology | Humans | Gene Expression Regulation | Cell Lineage | Animals | Models, Biological | T-Lymphocyte Subsets - metabolism | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Cell Differentiation | Cytokines - biosynthesis | Medical research | Immunology | Cellular biology | Index Medicus
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8. Full Text Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
by Brenchley, Jason M and Paiardini, Mirko and Knox, Kenneth S and Asher, Ava I and Cervasi, Barbara and Asher, Tedi E and Scheinberg, Phillip and Price, David A and Hage, Chadi A and Kholi, Lisa M and Khoruts, Alexander and Frank, Ian and Else, James and Schacker, Timothy and Silvestri, Guido and Douek, Daniel C
Blood, ISSN 0006-4971, 10/2008, Volume 112, Issue 7, pp. 2826 - 2835
Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases | Gastrointestinal Tract - virology | Th1 Cells - pathology | Humans | Antigens, Bacterial - immunology | Bronchoalveolar Lavage | Cercocebus atys | Antigens, Fungal - immunology | Epitopes | Lymphocyte Depletion | Gastrointestinal Tract - pathology | T-Lymphocytes, Helper-Inducer - virology | Th1 Cells - virology | Gastrointestinal Tract - immunology | HIV Infections - immunology | Phenotype | Animals | T-Lymphocytes, Helper-Inducer - immunology | Lentivirus Infections - immunology | Cell Differentiation | T-Lymphocytes, Helper-Inducer - pathology | Simian Immunodeficiency Virus - immunology | Index Medicus | Abridged Index Medicus | Immunobiology
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9. Full Text CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques
by McGary, Colleen S and Deleage, Claire and Harper, Justin and Micci, Luca and Ribeiro, Susan P and Paganini, Sara and Kuri-Cervantes, Leticia and Benne, Clarisse and Ryan, Emily S and Balderas, Robert and Jean, Sherrie and Easley, Kirk and Marconi, Vincent and Silvestri, Guido and Estes, Jacob D and Sekaly, Rafick-Pierre and Paiardini, Mirko
Immunity (Cambridge, Mass.), ISSN 1074-7613, 10/2017, Volume 47, Issue 4, pp. 776 - 788.e5
SIV | animal models | HIV | latent viral reservoir | regulatory T cells | co-inhibitory receptors | CTLA-4 | T follicular helper cells | PD-1 | regulatory T cells | Life Sciences & Biomedicine | Immunology | Science & Technology | Humans | Host-Pathogen Interactions - drug effects | Macaca mulatta | Immunologic Memory - drug effects | Host-Pathogen Interactions - immunology | T-Lymphocytes, Helper-Inducer - virology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - drug effects | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | HIV-1 - physiology | In Situ Hybridization | T-Lymphocytes, Helper-Inducer - immunology | Lymph Nodes - drug effects | CD4-Positive T-Lymphocytes - virology | Immunologic Memory - immunology | Simian Immunodeficiency Virus - immunology | Anti-Retroviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | Lymph Nodes - virology | Lymph Nodes - immunology | CTLA-4 Antigen - immunology | Simian Immunodeficiency Virus - physiology | Microscopy, Confocal | HIV-1 - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Simian Acquired Immunodeficiency Syndrome - immunology | HIV Infections - drug therapy | Programmed Cell Death 1 Receptor - immunology | Simian Immunodeficiency Virus - drug effects | CD4-Positive T-Lymphocytes - drug effects | T-Lymphocytes, Regulatory - virology | Therapy | PD-1 protein | Memory | Viruses | Infections | Lymphocytes T | Lymph nodes | CTLA-4 protein | Lymphocytes | Antiretroviral agents | Immunotherapy | Human immunodeficiency virus--HIV | Drug therapy | Deoxyribonucleic acid--DNA | Spleen | Antiretroviral drugs | Immunological memory | Memory cells | Immunoregulation | Latent infection | Monkeys & apes | Antiretroviral therapy | CD4 antigen | Lymphocytes B | Replication | Index Medicus
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