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Science Translational Medicine, ISSN 1946-6234, 05/2010, Volume 2, Issue 32, pp. 32ra36 - ra36
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2009, Volume 5, Issue 2, p. e1000295
Chronic immune activation and progression to AIDS are observed after SIV infection in macaques but not in natural host primate species. To better understand... 
DENDRITIC CELLS | HELPER-CELLS | INDOLEAMINE 2,3-DIOXYGENASE | AFRICAN-GREEN MONKEYS | SOOTY MANGABEYS | MICROBIOLOGY | VIRAL REPLICATION | GROWTH-FACTOR-BETA | VIROLOGY | SIMIAN IMMUNODEFICIENCY VIRUS | IMMUNE ACTIVATION | PARASITOLOGY | DISEASE PROGRESSION | T-Lymphocyte Subsets - immunology | Oligonucleotide Array Sequence Analysis | Interleukin-17 - immunology | Cercopithecus aethiops | Colon - immunology | Male | RNA, Viral - blood | Viral Load | T-Lymphocytes, Helper-Inducer - virology | T-Lymphocytes, Regulatory - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Flow Cytometry | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Statistics, Nonparametric | RNA, Viral - metabolism | Cytokines - immunology | Macaca nemestrina | Cytokines - metabolism | Lymphocyte Activation | Lymph Nodes - metabolism | RNA, Viral - analysis | Lymph Nodes - immunology | Colon - metabolism | Interleukin-17 - metabolism | Animals | Analysis of Variance | Simian Acquired Immunodeficiency Syndrome - immunology | CD8-Positive T-Lymphocytes - virology | Simian Immunodeficiency Virus | CD8-Positive T-Lymphocytes - immunology | T-Lymphocytes, Regulatory - virology | Immune response | AIDS (Disease) | Physiological aspects | Development and progression | Research | Simian immunodeficiency virus | T cells | Risk factors | HIV | Acquired immune deficiency syndrome | Primates | AIDS | Infections | Human immunodeficiency virus | Immune system
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2017, Volume 47, Issue 4, pp. 776 - 788.e5
Antiretroviral therapy (ART) suppresses viral replication in HIV-infected individuals but does not eliminate the reservoir of latently infected cells. Recent... 
SIV | animal models | HIV | latent viral reservoir | regulatory T cells | co-inhibitory receptors | CTLA-4 | T follicular helper cells | PD-1 | regulatory T cells | TGF-BETA | REPLICATION | RESERVOIR | REGULATORY CELLS | IMMUNE ACTIVATION | GENE-EXPRESSION | IMMUNODEFICIENCY VIRUS-INFECTION | IMMUNOLOGY | CHRONIC HIV-INFECTION | FOLLICULAR HELPER-CELLS | Humans | Host-Pathogen Interactions - drug effects | Macaca mulatta | Immunologic Memory - drug effects | Host-Pathogen Interactions - immunology | T-Lymphocytes, Helper-Inducer - virology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - drug effects | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | HIV-1 - physiology | In Situ Hybridization | T-Lymphocytes, Helper-Inducer - immunology | Lymph Nodes - drug effects | CD4-Positive T-Lymphocytes - virology | Immunologic Memory - immunology | Simian Immunodeficiency Virus - immunology | Anti-Retroviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | Lymph Nodes - virology | Lymph Nodes - immunology | CTLA-4 Antigen - immunology | Simian Immunodeficiency Virus - physiology | Microscopy, Confocal | HIV-1 - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Simian Acquired Immunodeficiency Syndrome - immunology | HIV Infections - drug therapy | Programmed Cell Death 1 Receptor - immunology | Simian Immunodeficiency Virus - drug effects | CD4-Positive T-Lymphocytes - drug effects | T-Lymphocytes, Regulatory - virology | Therapy | PD-1 protein | Memory | Viruses | Infections | Lymphocytes T | Lymph nodes | CTLA-4 protein | Lymphocytes | Antiretroviral agents | Immunotherapy | Human immunodeficiency virus--HIV | Drug therapy | Deoxyribonucleic acid--DNA | Spleen | Antiretroviral drugs | Immunological memory | Memory cells | Immunoregulation | Latent infection | Monkeys & apes | Antiretroviral therapy | CD4 antigen | Lymphocytes B | Replication | Reservoirs
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 683 - 690
Journal Article
European Journal of Immunology, ISSN 0014-2980, 02/2013, Volume 43, Issue 2, pp. 458 - 467
HCV is remarkable at disrupting human immunity to establish chronic infection. The accumulation of T reg cells at the site of infection and upregulation of... 
HCV | Hepatocytes | al‐9 | Immune modulation | Tim‐3 | Gal-9 | Tim-3 | IMMUNITY | GALECTIN-9 | MECHANISMS | IMMUNOLOGY | FOXP3 | BALANCE | SUPPRESSES | EXPRESSION | PD-1 | Forkhead Transcription Factors - immunology | Hepatitis C, Chronic - metabolism | T-Lymphocytes, Regulatory - metabolism | Hepacivirus - immunology | Coculture Techniques | Humans | Hepatitis C, Chronic - virology | Hepatocytes - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-2 Receptor alpha Subunit - genetics | Forkhead Transcription Factors - metabolism | Galectins - immunology | Membrane Proteins - metabolism | CD4-Positive T-Lymphocytes - virology | Interleukin-2 Receptor alpha Subunit - immunology | Transforming Growth Factor beta - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Membrane Proteins - immunology | Forkhead Transcription Factors - genetics | Hepatocytes - immunology | Hepatitis A Virus Cellular Receptor 2 | Transforming Growth Factor beta - genetics | Interleukin-2 Receptor alpha Subunit - metabolism | Hepatitis C, Chronic - immunology | Hepatocytes - virology | Hepatitis C, Chronic - genetics | Galectins - genetics | Galectins - metabolism | Transforming Growth Factor beta - metabolism | T-Lymphocytes, Regulatory - virology | Antiviral agents | Automobile driving | Bone morphogenetic proteins | Hepatitis C virus | T cells | Transforming growth factors | Motor vehicle driving | Infections | Immunology | Lymphocytes | Cells
Journal Article