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1. Full Text Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development
by Takeuchi, Jun K and Mileikovskaia, Maria and Koshiba-Takeuchi, Kazuko and Heidt, Analeah B and Mori, Alessandro D and Arruda, Eric P and Gertsenstein, Marina and Georges, Romain and Davidson, Lorinda and Mo, Rong and Hui, Chi-Chung and Henkelman, R. Mark and Nemer, Mona and Black, Brian L and Nagy, Andras and Bruneau, Benoit G
Development, ISSN 0950-1991, 05/2005, Volume 132, Issue 10, pp. 2463 - 2474
Heart | Motoneurons | Embryo | RNAi | Transcription factors | Optical projection tomography | Mouse | Tbx20 | T-box
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2. Full Text Unilaterale pulmonale Agenesie, Aplasie und Dysplasie
by Dembinski, J and Kroll, M and Lewin, M and Winkler, P
Zeitschrift für Geburtshilfe und Neonatologie, ISSN 0948-2393, 04/2009, Volume 213, Issue 2, pp. 56 - 61
Zusammenfassung Unilaterale pulmonale Fehlbildungen sind seltene, ätiologisch ungeklärte Ereignisse mit grosser klinischer Variabilität. Neonatale Symptomatik... 
Übersicht | Lung malformation | Embryology | T-box genes | Pitx2 | FGF 10
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3. Full Text Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin
by Mullen, Alan C and Takemoto, Naofumi and Ahmed, Rafi and Kaech, Susan M and Miller, Joseph D and Palanivel, Vikram R and Orange, Jordan S and Longworth, Sarah A and Gasink, Christopher R and Russ, Andreas P and Lindsten, Tullia and Reiner, Steven L and Intlekofer, Andrew M and Northrup, John T and Goldrath, Ananda W and Ryan, Kenneth and Gapin, Laurent and Wherry, E John
Nature Immunology, ISSN 1529-2908, 12/2005, Volume 6, Issue 12, pp. 1236 - 1244
Two seemingly unrelated hallmarks of memory CD8(+) T cells are cytokine-driven proliferative renewal after pathogen clearance and a latent effector program in... 
LINEAGE COMMITMENT | NATURAL-KILLER | PROTECTIVE IMMUNITY | IFN-GAMMA PRODUCTION | MARROW-DERIVED CELLS | CD8-T-CELL MEMORY | INTERLEUKIN-2 RECEPTOR-BETA | IMMUNOLOGY | HOMEOSTATIC PROLIFERATION | TRANSCRIPTION FACTOR | CUTTING EDGE | T-Box Domain Proteins - physiology | Transcription Factors - physiology | Humans | Mice, Inbred C57BL | Cells, Cultured | T-Box Domain Proteins - biosynthesis | Receptors, Interleukin-2 - metabolism | Mice, Transgenic | Interleukin-15 - deficiency | T-Box Domain Proteins - genetics | CD8-Positive T-Lymphocytes - physiology | T-Box Domain Proteins - metabolism | Mice, Knockout | Immunologic Memory - physiology | Phenotype | Animals | Interleukin-15 - genetics | Mice | Transcription factors | Gene mutations | CD8 lymphocytes | Physiological aspects | Genetic aspects | Research | Health aspects
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4. Full Text Complementarity and redundancy of IL-22-producing innate lymphoid cells
by Rankin, Lucille C and Girard-Madoux, Mathilde J H and Seillet, Cyril and Mielke, Lisa A and Kerdiles, Yann and Fenis, Aurore and Wieduwild, Elisabeth and Putoczki, Tracy and Mondot, Stanislas and Lantz, Olivier and Demon, Dieter and Papenfuss, Anthony T and Smyth, Gordon K and Lamkanfi, Mohamed and Carotta, Sebastian and Renauld, Jean-Christophe and Shi, Wei and Carpentier, Sabrina and Soos, Tim and Arendt, Christopher and Ugolini, Sophie and Huntington, Nicholas D and Belz, Gabrielle T and Vivier, Eric
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 179 - 186
Intestinal T cells and group 3 innate lymphoid cells (ILC3 cells) control the composition of the microbiota and gut immune responses. Within the gut, ILC3... 
IL-22 PRODUCTION | NATURAL-KILLER-CELLS | NK CELLS | COMMENSAL BACTERIA | INFLAMMATION | HOST-DEFENSE | INTERLEUKIN-22 | INFECTION | T-CELL | IMMUNOLOGY | LYMPHOCYTES | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Transcriptome | Homeostasis | Male | Gene Expression Profiling | Lymphocyte Subsets - immunology | Enterobacteriaceae Infections - immunology | Lymphocyte Subsets - metabolism | Lymphocytes - immunology | Enterobacteriaceae Infections - genetics | Female | Interleukins - biosynthesis | Myeloid Cell Leukemia Sequence 1 Protein - deficiency | Disease Models, Animal | Lymphocytes - metabolism | Citrobacter rodentium - immunology | Signal Transduction | T-Box Domain Proteins - deficiency | Enterobacteriaceae Infections - metabolism | Enterobacteriaceae Infections - mortality | Gene Expression Regulation | Mice, Transgenic | Enterobacteriaceae Infections - pathology | Immunity, Innate | T-Box Domain Proteins - genetics | Myeloid Cell Leukemia Sequence 1 Protein - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | Animals | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Mice | Cluster Analysis | Complications and side effects | Care and treatment | Microbiota (Symbiotic organisms) | Interleukins | Gastrointestinal diseases | Influence | Research | Health aspects | Life Sciences | Immunology
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5. Full Text IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
by Fernando, Romaine I and Castillo, Marianne D and Litzinger, Mary and Hamilton, Duane H and Palena, Claudia
Cancer Research, ISSN 0008-5472, 08/2011, Volume 71, Issue 15, pp. 5296 - 5306
The switch of tumor cells from an epithelial to a mesenchymal-like phenotype [designated as epithelial-to-mesenchymal transition (EMT)] is known to induce... 
BREAST-CARCINOMA | STEM-CELLS | IN-VITRO | ONCOLOGY | SERUM INTERLEUKIN-8 | PROSTATE-CANCER | METASTATIC PHENOTYPE | MALIGNANT-MELANOMA | TUMOR-GROWTH | EXPRESSION | PROGRESSION | Receptors, Interleukin-8 - genetics | T-Box Domain Proteins - physiology | Breast Neoplasms - secretion | Fibronectins - biosynthesis | Carcinoma - secretion | T-Box Domain Proteins - antagonists & inhibitors | Epithelial-Mesenchymal Transition - physiology | Humans | Neoplasm Proteins - physiology | T-Box Domain Proteins - biosynthesis | Culture Media, Conditioned - pharmacology | Culture Media, Serum-Free | Interleukin-8 - physiology | Neoplasm Proteins - antagonists & inhibitors | Bystander Effect | Tumor Microenvironment - physiology | Recombinant Fusion Proteins - antagonists & inhibitors | Cell Line, Tumor - pathology | Receptors, Interleukin-8 - biosynthesis | Cell Line, Tumor - secretion | Gene Expression Regulation, Neoplastic - drug effects | Intercellular Signaling Peptides and Proteins - secretion | Carcinoma - pathology | Neoplasm Proteins - genetics | Pancreatic Neoplasms - secretion | Promoter Regions, Genetic | Chemokines - secretion | Neoplasm Invasiveness | Neoplasm Proteins - biosynthesis | Pancreatic Neoplasms - pathology | RNA, Small Interfering - pharmacology | Cytokines - secretion | Fetal Proteins - physiology | Fetal Proteins - antagonists & inhibitors | Fetal Proteins - biosynthesis | T-Box Domain Proteins - genetics | Breast Neoplasms - pathology | Fetal Proteins - genetics | Fibronectins - genetics | Cell Movement | Brachyury | tumor microenvironment | IL-8 | metastasis | EMT
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6. Full Text The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells
by Powell, Nick and Walker, Alan W and Stolarczyk, Emilie and Canavan, James B and Gökmen, M. Refik and Marks, Ellen and Jackson, Ian and Hashim, Ahmed and Curtis, Michael A and Jenner, Richard G and Howard, Jane K and Parkhill, Julian and MacDonald, Thomas T and Lord, Graham M
Immunity, ISSN 1074-7613, 10/2012, Volume 37, Issue 4, pp. 674 - 684
Mice lacking the transcription factor T-bet in the innate immune system develop microbiota-dependent colitis. Here, we show that interleukin-17A... 
COLITIS | DATABASE | TYPHLITIS | LOCI | MUCOSAL | IMMUNOLOGY | DEFICIENCY | ADULT | IL-7 | DNA-Binding Proteins - immunology | Signal Transduction | T-Box Domain Proteins - deficiency | Cells, Cultured | Helicobacter - immunology | Colitis, Ulcerative - pathology | T-Box Domain Proteins - immunology | Immunity, Innate | Colitis, Ulcerative - immunology | DNA-Binding Proteins - deficiency | Mice, Knockout | Animals | Lymphocytes - immunology | Colitis, Ulcerative - microbiology | Mice | Mice, Inbred BALB C | Chronic Disease | Receptors, Interleukin-7 - immunology | Inflammatory bowel disease | Medical research | Cytokines | Rodents | Immune system
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7. Full Text Amyloid-like Self-Assembly of a Cellular Compartment
by Boke, Elvan and Ruer, Martine and Wühr, Martin and Coughlin, Margaret and Lemaitre, Regis and Gygi, Steven P and Alberti, Simon and Drechsel, David and Hyman, Anthony A and Mitchison, Timothy J
Cell, ISSN 0092-8674, 07/2016, Volume 166, Issue 3, pp. 637 - 650
Most vertebrate oocytes contain a Balbiani body, a large, non-membrane-bound compartment packed with RNA, mitochondria, and other organelles. Little is known... 
velo1 | FIBRIL FORMATION | XENOPUS-LAEVIS | LOCALIZATION | MITOCHONDRIAL CLOUD | DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE OOCYTES | NEURODEGENERATION | BALBIANI BODY | GERM PLASM | AGGREGATION | CELL BIOLOGY | T-Box Domain Proteins - chemistry | Xenopus Proteins - genetics | Xenopus laevis | Zebrafish | Mitochondria - metabolism | Prions - chemistry | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Protein Transport | Xenopus Proteins - chemistry | Oocytes - cytology | Organelle Biogenesis | Sf9 Cells | Animals | Amyloid - metabolism | Thiazoles | Protein Domains | Recombinant Fusion Proteins - genetics | Female | Xenopus Proteins - metabolism | Organelles - metabolism | Fluorescent Dyes | Proteins | RNA | Molecular biology | Cells | Polymerization
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8. Full Text Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation
by Hu, Gangqing and Tang, Qingsong and Sharma, Suveena and Yu, Fang and Escobar, Thelma M and Muljo, Stefan A and Zhu, Jinfang and Zhao, Keji
Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 11, pp. 1190 - 1198
Although intergenic long noncoding RNAs (lincRNAs) have been linked to gene regulation in various tissues, little is known about lincRNA transcriptomes in the... 
STEM-CELLS | INTERFERON | INTEGRATIVE ANNOTATION | GENE-EXPRESSION | POPULATIONS | IMMUNOLOGY | GENOME-WIDE IDENTIFICATION | TRANSCRIPTION FACTOR | SEQ | CUTTING EDGE | REVEALS | GATA3 Transcription Factor - genetics | GATA3 Transcription Factor - immunology | STAT4 Transcription Factor - metabolism | STAT6 Transcription Factor - genetics | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Transcriptome - immunology | Genetic Loci | Th1 Cells - immunology | RNA, Long Noncoding - immunology | Th1 Cells - metabolism | Th17 Cells - metabolism | Precursor Cells, T-Lymphoid - metabolism | Precursor Cells, T-Lymphoid - cytology | Th17 Cells - cytology | Cell Differentiation | GATA3 Transcription Factor - metabolism | STAT4 Transcription Factor - immunology | Signal Transduction | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Molecular Sequence Annotation | Th2 Cells - cytology | RNA, Long Noncoding - genetics | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | T-Box Domain Proteins - genetics | Th2 Cells - metabolism | T-Box Domain Proteins - metabolism | Animals | Protein Binding | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Mice | Th1 Cells - cytology | Precursor Cells, T-Lymphoid - immunology | Cell Movement | Physiological aspects | Genetic aspects | Research | Cell differentiation | Gene expression | T cells | Cell migration
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9. Full Text Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
by van Helden, Mary J and Goossens, Steven and Daussy, Cécile and Mathieu, Anne-Laure and Faure, Fabrice and Marçais, Antoine and Vandamme, Niels and Farla, Natalie and Mayol, Katia and Viel, Sébastien and Degouve, Sophie and Debien, Emilie and Seuntjens, Eve and Conidi, Andrea and Chaix, Julie and Mangeot, Philippe and de Bernard, Simon and Buffat, Laurent and Haigh, Jody J and Huylebroeck, Danny and Lambrecht, Bart N and Berx, Geert and Walzer, Thierry
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 12, pp. 2015 - 2025
Natural killer (NK) cell maturation is a tightly controlled process that endows NK cells with functional competence and the capacity to recognize target cells.... 
MEDICINE, RESEARCH & EXPERIMENTAL | HOMEOSTASIS | IN-VIVO | MOUSE | DISEASE | TRAFFICKING | RECEPTOR | MICE | IMMUNOLOGY | PROTEINS | EXPRESSION | Bone Marrow - immunology | Homeodomain Proteins - metabolism | Humans | Cell Survival - genetics | Melanoma, Experimental - metabolism | Homeodomain Proteins - immunology | T-Box Domain Proteins - immunology | Zinc Finger E-box Binding Homeobox 2 | Flow Cytometry | Melanoma, Experimental - immunology | Bone Marrow - metabolism | Gene Expression - immunology | Killer Cells, Natural - immunology | Repressor Proteins - metabolism | Cytokines - immunology | Mice, Inbred C57BL | Cells, Cultured | Cytokines - secretion | Repressor Proteins - genetics | Mice, Transgenic | Cell Survival - immunology | Reverse Transcriptase Polymerase Chain Reaction | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | Animals | Melanoma, Experimental - genetics | Repressor Proteins - immunology | Cell Line, Tumor | Killer Cells, Natural - metabolism
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10. Full Text The molecular signature of tissue resident memory CD8 T cells isolated from the brain
by Wakim, Linda M and Woodward-Davis, Amanda and Liu, Ruijie and Hu, Yifang and Villadangos, Jose and Smyth, Gordon and Bevan, Michael J
Journal of Immunology, ISSN 0022-1767, 10/2012, Volume 189, Issue 7, pp. 3462 - 3471
Tissue resident memory (Trm) CD8 T cells represent a newly described memory T cell population. We have previously characterized a population of Trmcells that... 
IMMUNITY | HERPES-SIMPLEX-VIRUS | NONLYMPHOID TISSUE | WEST-NILE-VIRUS | INFECTION | ABSENCE | IMMUNOLOGY | EXPRESSION | LYMPHOCYTES | CD8-Positive T-Lymphocytes - cytology | Antigens, CD - biosynthesis | Humans | T-Box Domain Proteins - biosynthesis | T Cell Transcription Factor 1 - blood | T-Box Domain Proteins - blood | Antigens, CD - genetics | Organ Specificity - immunology | Brain - metabolism | Organ Specificity - genetics | Vesicular Stomatitis - metabolism | CD8-Positive T-Lymphocytes - metabolism | Immunologic Memory - genetics | Vesicular Stomatitis - pathology | Brain - cytology | Cell Separation | Mice, Inbred C57BL | Cells, Cultured | Immunophenotyping | Mice, Transgenic | T-Box Domain Proteins - genetics | Integrin alpha Chains - blood | Mice, Knockout | T Cell Transcription Factor 1 - genetics | Vesicular Stomatitis - immunology | T Cell Transcription Factor 1 - biosynthesis | Antigens, CD - blood | Animals | Integrin alpha Chains - biosynthesis | Mice | CD8-Positive T-Lymphocytes - immunology | Brain - immunology | Integrin alpha Chains - genetics | Vesicular stomatitis Indiana virus - immunology
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11. Full Text Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2
by Manvendra K. Singh and Vincent M. Christoffels and José M. Dias and Mark-Oliver Trowe and Marianne Petry and Karin Schuster-Gossler and Antje Bürger and Johan Ericson and Andreas Kispert
Development, ISSN 0950-1991, 06/2005, Volume 132, Issue 12, pp. 2697 - 2707
Tbx20 , a member of the T-box family of transcriptional regulators, shows evolutionary conserved expression in the developing heart. In the mouse, Tbx20 is... 
Heart | Myocardium | Anterior heart field | Bmp | T-box | CELLS | BHLH TRANSCRIPTION FACTOR | EXPRESSION ANALYSIS | ZEBRAFISH | MOUSE EMBRYOGENESIS | DROSOPHILA HEART | myocardium | T-BOX GENE | DEVELOPMENTAL BIOLOGY | heart | MORPHOGENESIS | HOLT-ORAM-SYNDROME | anterior heart field | Heart - anatomy & histology | Cell Proliferation | T-Box Domain Proteins - deficiency | Heart - embryology | Repressor Proteins - genetics | Mutation - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | Myocardium - cytology | Animals | Gene Expression Regulation, Developmental | Myocardium - metabolism | Cell Differentiation | Mice | Body Patterning - genetics | Repressor Proteins - metabolism | Apoptosis
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12. Full Text Foxo Transcription Factors Control Regulatory T Cell Development and Function
by Kerdiles, Yann M and Stone, Erica L and Beisner, Daniel L and McGargill, Maureen A and Ch'en, Irene L and Stockmann, Christian and Katayama, Carol D and Hedrick, Stephen M
Immunity, ISSN 1074-7613, 2010, Volume 33, Issue 6, pp. 890 - 904
Foxo transcription factors integrate extrinsic signals to regulate cell division, differentiation and survival, and specific functions of lymphoid and myeloid... 
LINEAGE COMMITMENT | THYMOCYTE DEVELOPMENT | L-SELECTIN | DENDRITIC CELLS | LYMPHOID ORGANS | RECEPTOR | MICE | AKT | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Forkhead Transcription Factors - immunology | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Antigens, CD - biosynthesis | Th1-Th2 Balance | Autoimmunity - genetics | T-Box Domain Proteins - immunology | Antigens, CD - genetics | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Forkhead Transcription Factors - metabolism | Cell Differentiation | Transforming Growth Factor beta - immunology | Forkhead Transcription Factors - biosynthesis | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Cells, Cultured | Forkhead Transcription Factors - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | CTLA-4 Antigen | Cell Lineage | Animals | T-Lymphocyte Subsets - pathology | T-Lymphocyte Subsets - metabolism | Immune Tolerance - genetics | Forkhead Box Protein O1 | Mice | Transforming Growth Factor beta - metabolism | DNA binding proteins | Paralysis | T cells | Transforming growth factors | Pancreatitis | Transcription factors | Lymphocytes | DNA repair | Rodents | Immune system | Apoptosis
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13. Full Text Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium
by Yusuke Watanabe and Stéphane Zaffran and Atsushi Kuroiwa and Hiroaki Higuchi and Toshihiko Ogura and Richard P. Harvey and Robert G. Kelly and Margaret Buckingham
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 45, pp. 18273 - 18280
During cardiogenesis, Fibroblast Growth Factor (Fgf10) is expressed in the anterior second heart field. Together with Fibroblast growth factor 8 (Fgf8), Fgf10... 
Heart | Transgenic animals | Heart ventricles | Genes | Myocardium | Promoter regions | Transgenes | Embryos | Progenitor cells | Binding sites | Transcriptional regulation | Mouse embryo | TRANSCRIPTION FACTORS | CELLS | ARTERIAL POLE | MOUSE HEART | transcriptional regulation | MULTIDISCIPLINARY SCIENCES | OUTFLOW TRACT | mouse embryo | ENHANCER | ISL1 | DIFFERENTIATION | EXPRESSION | FGF10 | Protein Binding - genetics | LIM-Homeodomain Proteins - metabolism | Heart - embryology | Homeodomain Proteins - metabolism | Molecular Sequence Data | Chromosomes, Artificial, Bacterial - genetics | Gene Expression Regulation, Developmental | Base Pairing - genetics | Base Sequence | Myocardium - metabolism | Transcription, Genetic | Fibroblast Growth Factor 10 - genetics | Binding Sites | Fibroblast Growth Factor 10 - metabolism | Transgenes - genetics | Mice, Transgenic | Transcription Factors - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Homeodomain Proteins - genetics | Regulatory Sequences, Nucleic Acid - genetics | T-Box Domain Proteins - metabolism | Transcription Factors - metabolism | Homeobox Protein Nkx-2.5 | LIM-Homeodomain Proteins - genetics | Animals | Genes, Switch - genetics | Models, Biological | Mice | Physiological aspects | Fibroblast growth factors | Genetic aspects | Research | Genetic transcription | Genetic regulation | Health aspects | Heart muscle | Regulatory Sequences, Nucleic Acid | Cellular Biology | Life Sciences | Chromosomes, Artificial, Bacterial | Genes, Switch | Down-Regulation | Base Pairing | Fibroblast Growth Factor 10 | Homeodomain Proteins | Protein Binding | LIM-Homeodomain Proteins | Transcription Factors | T-Box Domain Proteins | Biological Sciences
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