2009, ISBN 1849290016, xi, 101
Book
2006, ISBN 9780955166907
eBook
2005, ISBN 1591472458, xx, 272
Book
2005, ISBN 9211302471, xviii, 170
Book
2003, ISBN 9789211201666
eBook
Annals of the New York Academy of Sciences, ISSN 0077-8923, 12/2011, Volume 1246, Issue 1, pp. 26 - 33
The discovery that loss‐of‐function mutations in the gene DOCK8 are responsible for most forms of autosomal recessive hyper‐IgE syndrome and some forms of...
hyper‐IgE syndrome | DOCK8 | lymphopenia | combined immunodeficiency | Hyper-IgE syndrome | Combined immunodeficiency | Lymphopenia | STAT3 MUTATIONS | MULTIDISCIPLINARY SCIENCES | hyper-IgE syndrome | LUNG-CANCER | HYPERIMMUNOGLOBULIN-E SYNDROME | RAC ACTIVATOR DOCK2 | GENETICS & HEREDITY | STEM-CELL TRANSPLANTATION | HOMOZYGOUS DELETIONS | T-CELLS | IMMUNODEFICIENCY | CYTOKINESIS 8 DOCK8 | Job Syndrome - immunology | Central Nervous System Diseases - genetics | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - genetics | Humans | Immunoglobulin E - metabolism | Central Nervous System Diseases - immunology | Animals | B-Lymphocytes - immunology | Immunoglobulin E - immunology | Guanine Nucleotide Exchange Factors - metabolism | Immunologic Deficiency Syndromes - genetics | T-Lymphocytes - immunology | Mice | Immunologic Deficiency Syndromes - immunology | Disease Models, Animal | Autoimmunity | Immunoglobulin E | Disease susceptibility | Bacterial infections | Analysis | Immunodeficiency | Allergies | Mutation | Mutations | Elevated | Abnormalities | Genes | Bacteria | Allergic diseases | Serums | Patients
hyper‐IgE syndrome | DOCK8 | lymphopenia | combined immunodeficiency | Hyper-IgE syndrome | Combined immunodeficiency | Lymphopenia | STAT3 MUTATIONS | MULTIDISCIPLINARY SCIENCES | hyper-IgE syndrome | LUNG-CANCER | HYPERIMMUNOGLOBULIN-E SYNDROME | RAC ACTIVATOR DOCK2 | GENETICS & HEREDITY | STEM-CELL TRANSPLANTATION | HOMOZYGOUS DELETIONS | T-CELLS | IMMUNODEFICIENCY | CYTOKINESIS 8 DOCK8 | Job Syndrome - immunology | Central Nervous System Diseases - genetics | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - genetics | Humans | Immunoglobulin E - metabolism | Central Nervous System Diseases - immunology | Animals | B-Lymphocytes - immunology | Immunoglobulin E - immunology | Guanine Nucleotide Exchange Factors - metabolism | Immunologic Deficiency Syndromes - genetics | T-Lymphocytes - immunology | Mice | Immunologic Deficiency Syndromes - immunology | Disease Models, Animal | Autoimmunity | Immunoglobulin E | Disease susceptibility | Bacterial infections | Analysis | Immunodeficiency | Allergies | Mutation | Mutations | Elevated | Abnormalities | Genes | Bacteria | Allergic diseases | Serums | Patients
Journal Article
1991, ISBN 0309044286, x, 146
Book
1991, ISBN 0309044286, x, 146
Book
AIDS research and human retroviruses, ISSN 0889-2229, 1987
Journal
2015, Transformations: studies in the history of science and technology, ISBN 9780262028660, xii, 336
In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping...
HIV Infections | Patents | genetics | Genetic genealogy | Genes | Acquired Immunodeficiency Syndrome | Receptors, CCR5 | Continental Population Groups | HIV (Viruses) | Human population genetics | Patents as Topic | HIV infections | Clinical & internal medicine | Health Sciences | Genetics - Patents | Medical sciences | Pharmaceutical industry | Chemokines | Intellectual property
HIV Infections | Patents | genetics | Genetic genealogy | Genes | Acquired Immunodeficiency Syndrome | Receptors, CCR5 | Continental Population Groups | HIV (Viruses) | Human population genetics | Patents as Topic | HIV infections | Clinical & internal medicine | Health Sciences | Genetics - Patents | Medical sciences | Pharmaceutical industry | Chemokines | Intellectual property
Book
2015, ISBN 9780393350845, 174
Book
Autoimmunity Reviews, ISSN 1568-9972, 2013, Volume 13, Issue 2, pp. 163 - 177
Abstract IgA is the most abundant immunoglobulin in the human body, and performs a very specialized role which involves mucosal immunity, development of...
Allergy and Immunology | Combined variable immunodeficiency (CVID) | Autoimmune disease | IgA | Immunoglobulins | Selective IgA deficiency | Immunodeficiency | PRIMARY IMMUNODEFICIENCY DISORDERS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | X-CHROMOSOME | SJOGRENS-SYNDROME | COMMON VARIABLE IMMUNODEFICIENCY | BLOOD-DONORS | SERUM IMMUNOGLOBULINS | T-CELL | IMMUNOLOGY | MYASTHENIA-GRAVIS | IMMUNOGLOBULIN-A DEFICIENCY | Autoimmunity | Bacterial infections | Immunoglobulin A | Immunoglobulin G
Allergy and Immunology | Combined variable immunodeficiency (CVID) | Autoimmune disease | IgA | Immunoglobulins | Selective IgA deficiency | Immunodeficiency | PRIMARY IMMUNODEFICIENCY DISORDERS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | X-CHROMOSOME | SJOGRENS-SYNDROME | COMMON VARIABLE IMMUNODEFICIENCY | BLOOD-DONORS | SERUM IMMUNOGLOBULINS | T-CELL | IMMUNOLOGY | MYASTHENIA-GRAVIS | IMMUNOGLOBULIN-A DEFICIENCY | Autoimmunity | Bacterial infections | Immunoglobulin A | Immunoglobulin G
Journal Article
Immunity, ISSN 1074-7613, 05/2014, Volume 40, Issue 5, pp. 720 - 733
Interleukin-10 (IL-10) is a pleiotropic anti-inflammatory cytokine produced and sensed by most hematopoietic cells. Genome-wide association studies and...
DEPENDENT COLITIS | CHRONIC ENTEROCOLITIS | INFLAMMATORY-BOWEL-DISEASE | DENDRITIC CELLS | ULCERATIVE-COLITIS | REGULATORY T-CELLS | NITRIC-OXIDE | LY6C(HI) MONOCYTES | IMMUNOLOGY | AND/OR NEUTROPHILS | PROSTAGLANDIN E-2 | Mice, Inbred C57BL | Cells, Cultured | Colitis, Ulcerative - genetics | Colitis, Ulcerative - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Animals | Intestinal Mucosa - immunology | Interleukin-10 - genetics | Receptors, Chemokine - biosynthesis | Mice | CX3C Chemokine Receptor 1 | Interleukin-10 - immunology | Macrophages - immunology | Intestinal Mucosa - pathology | Receptors, Interleukin-10 - genetics | Receptors, Interleukin-10 - immunology | Colitis | Interleukins | Macrophages | Gastrointestinal diseases | Analysis | Genomics | Inflammatory bowel disease | Flow cytometry | Rodents | Homeostasis | Software | Gene expression | Chemokines
DEPENDENT COLITIS | CHRONIC ENTEROCOLITIS | INFLAMMATORY-BOWEL-DISEASE | DENDRITIC CELLS | ULCERATIVE-COLITIS | REGULATORY T-CELLS | NITRIC-OXIDE | LY6C(HI) MONOCYTES | IMMUNOLOGY | AND/OR NEUTROPHILS | PROSTAGLANDIN E-2 | Mice, Inbred C57BL | Cells, Cultured | Colitis, Ulcerative - genetics | Colitis, Ulcerative - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Animals | Intestinal Mucosa - immunology | Interleukin-10 - genetics | Receptors, Chemokine - biosynthesis | Mice | CX3C Chemokine Receptor 1 | Interleukin-10 - immunology | Macrophages - immunology | Intestinal Mucosa - pathology | Receptors, Interleukin-10 - genetics | Receptors, Interleukin-10 - immunology | Colitis | Interleukins | Macrophages | Gastrointestinal diseases | Analysis | Genomics | Inflammatory bowel disease | Flow cytometry | Rodents | Homeostasis | Software | Gene expression | Chemokines
Journal Article
2011, ISBN 9780521186377, 312
It is now thirty years since the discovery of AIDS but its origins continue to puzzle doctors and scientists. Inspired by his own experiences working as an...
HIV infections | Etiology | Africa | AIDS (Disease) | Emerging infectious diseases
HIV infections | Etiology | Africa | AIDS (Disease) | Emerging infectious diseases
Book
2013, ISBN 9780804784221, xii, 274 pages
Book
2011, 1st ed., Care and Welfare, ISBN 9789089643599, 254
In 2003-2006, Patricia Henderson lived in the South African province of KwaZulu-Natal where she recorded the experiences of people living with HIV/AIDS. In...
Sociology | Anthropology | Local history | Handbooks, manuals, etc | United States | History, Local
Sociology | Anthropology | Local history | Handbooks, manuals, etc | United States | History, Local
Book
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 1, pp. 52 - 61
CD55 prevents convertase enzyme formation in the complement cascade, acting as a brake on complement activation. Inactivating mutations in CD55 result in...
Protein-Losing Enteropathies | Complement Activation | Intestine, Small | T-Lymphocytes | Humans | Child, Preschool | Complement Inactivating Agents | Infant | Male | Immunoglobulin A | Thrombosis | Syndrome | Journal Article | Complement System Proteins | Homozygote | Pedigree | Statistics, Nonparametric | Female | Mutation | CD55 Antigens | Child | MEDICINE, GENERAL & INTERNAL | ACTIVATION | INFLAMMATORY-BOWEL-DISEASE | HEMOLYTIC-UREMIC SYNDROME | CELL RESPONSES | COMPLEMENT REGULATORY PROTEIN | INAB PHENOTYPE | DECAY-ACCELERATING FACTOR | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | T-CELLS | Intestine, Small - pathology | CD55 Antigens - genetics | Protein-Losing Enteropathies - genetics | Complement System Proteins - metabolism | CD55 Antigens - blood | Complement Activation - genetics | T-Lymphocytes - metabolism | Complement Inactivating Agents - pharmacology | Protein-Losing Enteropathies - complications | Immunoglobulin A - blood | Thrombosis - genetics | Complement Activation - drug effects | Proteins | Molecular targeted therapy | Gene mutations | Gastrointestinal diseases | Analysis | Homeostasis | Research | Blood clot | Gastrointestinal tract diseases | Complement component C5a | Lymphocytes T | Cell activation | Immunology | Pain | Intestine | Hepatology | Gastroenterology | Malabsorption | Thromboembolism | Digestive tract | Age | Edema | Medical research | Lymphatic system | Hypersensitivity | Diarrhea | Inflammation | Heredity | Protein deficiency | Patients | Hereditary diseases | Complement activation | Infectious diseases | Decay-accelerating factor
Protein-Losing Enteropathies | Complement Activation | Intestine, Small | T-Lymphocytes | Humans | Child, Preschool | Complement Inactivating Agents | Infant | Male | Immunoglobulin A | Thrombosis | Syndrome | Journal Article | Complement System Proteins | Homozygote | Pedigree | Statistics, Nonparametric | Female | Mutation | CD55 Antigens | Child | MEDICINE, GENERAL & INTERNAL | ACTIVATION | INFLAMMATORY-BOWEL-DISEASE | HEMOLYTIC-UREMIC SYNDROME | CELL RESPONSES | COMPLEMENT REGULATORY PROTEIN | INAB PHENOTYPE | DECAY-ACCELERATING FACTOR | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | T-CELLS | Intestine, Small - pathology | CD55 Antigens - genetics | Protein-Losing Enteropathies - genetics | Complement System Proteins - metabolism | CD55 Antigens - blood | Complement Activation - genetics | T-Lymphocytes - metabolism | Complement Inactivating Agents - pharmacology | Protein-Losing Enteropathies - complications | Immunoglobulin A - blood | Thrombosis - genetics | Complement Activation - drug effects | Proteins | Molecular targeted therapy | Gene mutations | Gastrointestinal diseases | Analysis | Homeostasis | Research | Blood clot | Gastrointestinal tract diseases | Complement component C5a | Lymphocytes T | Cell activation | Immunology | Pain | Intestine | Hepatology | Gastroenterology | Malabsorption | Thromboembolism | Digestive tract | Age | Edema | Medical research | Lymphatic system | Hypersensitivity | Diarrhea | Inflammation | Heredity | Protein deficiency | Patients | Hereditary diseases | Complement activation | Infectious diseases | Decay-accelerating factor
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2018, Volume 141, Issue 4, pp. 1417 - 1426.e1
Allogeneic hematopoietic stem cell transplantation (HSCT) is used as a therapeutic approach for primary immunodeficiencies (PIDs). The best outcomes have been...
hematopoietic stem cell transplantation | CD3+ T-cell receptor αβ+ cell depletion | haploidentical | mismatched unrelated | Primary immunodeficiency | cell depletion | CD3 | T-cell receptor αβ | Busulfan - analogs & derivatives | Immunologic Deficiency Syndromes - therapy | Humans | Antilymphocyte Serum - immunology | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Thiotepa - immunology | Vidarabine - analogs & derivatives | Graft vs Host Disease - immunology | CD3 Complex - immunology | Vidarabine - immunology | Female | Graft vs Host Disease - prevention & control | Retrospective Studies | Transplantation Conditioning - methods | Busulfan - immunology | Immunologic Deficiency Syndromes - immunology | Child | Alemtuzumab - immunology | Antigens, CD19 - immunology | Graft-versus-host reaction | Transplants & implants | Liver | Prophylaxis | Stem cell transplantation | Transplantation | Lymphocytes T | Infections | Treosulfan | Drug resistance | Grafting | Hematopoietic stem cells | T-cell receptor | Demographics | Lymphocytes | Children | Busulfan | Conditioning | Cytomegalovirus | Immunoglobulins | CD19 antigen | Neutrophils | Health risks | Immunodeficiency | Transplants | CD3 antigen | T cell receptors | Patients | Survival | Hemopoiesis | Graft rejection | Rejection | Fludarabine | Grafts | Depletion | Globulins | Thymocytes | Adenoviruses | Stem cells | Monoclonal antibodies | Histocompatibility antigen HLA | Methods | Viral infections
hematopoietic stem cell transplantation | CD3+ T-cell receptor αβ+ cell depletion | haploidentical | mismatched unrelated | Primary immunodeficiency | cell depletion | CD3 | T-cell receptor αβ | Busulfan - analogs & derivatives | Immunologic Deficiency Syndromes - therapy | Humans | Antilymphocyte Serum - immunology | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Thiotepa - immunology | Vidarabine - analogs & derivatives | Graft vs Host Disease - immunology | CD3 Complex - immunology | Vidarabine - immunology | Female | Graft vs Host Disease - prevention & control | Retrospective Studies | Transplantation Conditioning - methods | Busulfan - immunology | Immunologic Deficiency Syndromes - immunology | Child | Alemtuzumab - immunology | Antigens, CD19 - immunology | Graft-versus-host reaction | Transplants & implants | Liver | Prophylaxis | Stem cell transplantation | Transplantation | Lymphocytes T | Infections | Treosulfan | Drug resistance | Grafting | Hematopoietic stem cells | T-cell receptor | Demographics | Lymphocytes | Children | Busulfan | Conditioning | Cytomegalovirus | Immunoglobulins | CD19 antigen | Neutrophils | Health risks | Immunodeficiency | Transplants | CD3 antigen | T cell receptors | Patients | Survival | Hemopoiesis | Graft rejection | Rejection | Fludarabine | Grafts | Depletion | Globulins | Thymocytes | Adenoviruses | Stem cells | Monoclonal antibodies | Histocompatibility antigen HLA | Methods | Viral infections
Journal Article