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Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2009, Volume 52, Issue 17, pp. 5365 - 5379
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2012, Volume 55, Issue 3, pp. 1303 - 1317
Journal Article
Neuropharmacology, ISSN 0028-3908, 02/2012, Volume 62, Issue 2, pp. 997 - 1003
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2010, Volume 53, Issue 13, pp. 4927 - 4937
Journal Article
Molecules, ISSN 1420-3049, 02/2013, Volume 18, Issue 2, pp. 2397 - 2418
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2014, Volume 82, pp. 426 - 438
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 08/2013, Volume 21, Issue 15, pp. 4559 - 4569
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 93, pp. 42 - 50
Combining tacrine with trolox in a single molecule, novel multifunctional hybrids have been designed and synthesized. All these hybrids showed ChE inhibitory... 
Antioxidant | Trolox | Alzheimer's disease | Hepatotoxicity | Tacrine | Cholinesterase | NO DONOR | TARGET-DIRECTED LIGANDS | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | RAT HEPATOCYTES | NEURODEGENERATIVE DISEASES | IN-VITRO | AMYLOID-BETA | ACETYLCHOLINESTERASE INHIBITORS | DERIVATIVES | Cholinesterase Inhibitors - pharmacokinetics | Male | Cholinesterase Inhibitors - chemical synthesis | PC12 Cells | Tacrine - adverse effects | Tacrine - pharmacology | Neuroprotective Agents - pharmacology | Tacrine - pharmacokinetics | Chromans - pharmacokinetics | Chromans - pharmacology | Neuroprotective Agents - pharmacokinetics | Swine | Picrates - chemistry | Drug Design | Molecular Structure | Biphenyl Compounds - chemistry | Neuroprotective Agents - adverse effects | Chromans - chemistry | Tacrine - chemistry | Cell Survival - drug effects | Chemical and Drug Induced Liver Injury - prevention & control | Alzheimer Disease - drug therapy | Rats | Alzheimer Disease - enzymology | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Blood-Brain Barrier - metabolism | Chromans - adverse effects | Neuroprotective Agents - chemical synthesis | Animals | Cholinesterase Inhibitors - pharmacology | Alzheimer Disease - metabolism | Cholinesterase Inhibitors - adverse effects | Antioxidants - adverse effects | Molecular Docking Simulation | Kinetics | Antioxidants - pharmacokinetics | In Vitro Techniques | Antioxidants | Enzyme inhibitors | Drug therapy | Analysis | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2015, Volume 89, pp. 296 - 303
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 11/2014, Volume 22, Issue 21, pp. 6089 - 6104
A series of tacrine-(β-carboline) hybrids (11a-q) were designed, synthesized and evaluated as multifunctional cholinesterase inhibitors against Alzheimer's... 
β-Amyloid aggregation | β-Carboline | Alzheimers disease | Antioxidant | Metal chelator | Tacrine | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | TACRINE HYBRIDS | RADICAL SCAVENGERS | CARBOLINE ALKALOIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | beta-Carboline | CHOLINESTERASE-INHIBITORS | BUTYRYLCHOLINESTERASE INHIBITORS | ANTIOXIDANT PROPERTIES | L-TRYPTOPHAN | beta-Amyloid aggregation | BIOLOGICAL EVALUATION | Alzheimer's disease | Cholinesterase Inhibitors - pharmacokinetics | Antioxidants - chemistry | Humans | Cholinesterase Inhibitors - chemistry | Carbolines - chemistry | Tacrine - pharmacology | Tacrine - pharmacokinetics | Chelating Agents - pharmacokinetics | Butyrylcholinesterase - metabolism | Amyloid beta-Peptides - metabolism | Drug Design | Tacrine - chemistry | Cell Line | Chelating Agents - chemistry | Alzheimer Disease - drug therapy | Electrophorus | Alzheimer Disease - enzymology | Antioxidants - pharmacology | Chelating Agents - pharmacology | Protein Aggregation, Pathological - drug therapy | Blood-Brain Barrier - metabolism | Animals | Cholinesterase Inhibitors - pharmacology | Alzheimer Disease - metabolism | Horses | Molecular Docking Simulation | Carbolines - pharmacokinetics | Antioxidants - pharmacokinetics | Acetylcholinesterase - metabolism | Protein Aggregation, Pathological - metabolism | Carbolines - pharmacology | Drug therapy | Analysis | Index Medicus
Journal Article
Tropical Medicine and International Health, ISSN 1360-2276, 02/2006, Volume 11, Issue 2, p. 136
Resume Evaluer la situation de la maladie du sommeil dans le centre-ouest de la Cote d'Ivoire de 2000 a 2003, en tenant compte des evenements survenus depuis... 
Tacrine
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2016, Volume 118, pp. 178 - 192
Journal Article
Journal Article