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International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
2005, ISBN 0444518231, Volume 15, Issue 2
Fever evoked by an exogenous pyrogen, either pathologically or by experimental interventions, is presumed to be mediated by endogenous pyrogenic cytokines,... 
tumour necrosis factor receptor type I | interleukin-1 family members | TRAF | phospholipase A2 | ACTH | PVN | IL-1R | interleukin-1 type I receptor | AP-1 | TNF | microsomal prostaglandin E synthase | Toll/interleukin-1 receptor domain | uncoupling protein | EP1–4 | | interleukin-1 beta-converting enzyme (also called caspase 1) | interleukin-1 receptor accessory protein-like | TGFβ-activated kinase | enzyme-linked immunoabsorbent assays | suppressors of cytokine signalling | alpha-melanocyte-stimulating hormone | nitric oxide synthase | cytochrome P-450 mono-oxygenase enzyme | hypothalamic-pituitary-adrenal axis | nitric oxide | POA | circumventricular organs | constitutive nitric oxide synthase | STATs | PLA2 | i.p | + | ELISAs | central nervous system | i.v | IRAK | gene-deleted heterozygous | SHP-2 | NF-IL-6 | PGN | HPA | IL-1F | lipopolysaccharide-binding protein | Mal | myeloid differentiation factor 88-adapter-like | tumour necrosis factor | lipopolysaccharide | MAP | cNOS | receptor-interacting protein | CNS | janus-associated kinase-signal transducer and activator of transcription | janus-associated kinases | LPS | gene-deleted homozygous | mitogen-activated protein kinase | interferons | MIP-1β | messenger RNA | sIL-6R | tumour necrosis factor receptor-associated factor | intracerebroventricular | α-MSH | PGs | SFO | ventromedial preoptic area | interleukin-1 receptor antagonist | interleukin-18 receptor (also known as interleukin-1 receptor-related protein) | IL-1RII | intraperitoneal | muramyl dipeptide | MEKK1 | interleukin-1 receptor-associated kinase | organum vasculosum lamin terminalis | Tollip | mitogen-activated protein kinase/ERK kinase 1 | ICE | tumour necrosis factor receptor type II | COX | Src-homology 2 domain containing | IL-1RAcP | i.c.v | toll-like receptor | SH2 | three-Ig-domain-containing interleukin-1 receptor-related protein | TIR | TAK | UCP | JNK | TRADD | TNFRI | IRF-3 | OVLT | ECSIT | adrenocorticotropic hormone | MyD88 | tumour necrosis factor receptor type I-associated death domain | nuclear factor interleukin-6 | activator protein 1 | interleukin-1 type II receptor | Ikappa B kinase complex | prostaglandin E2 | interleukin-1 receptor accessory protein | mitogen-activated protein | MDP | myeloid differentiation factor 88 | iNOS | IL-1Rrp2 | LBP | interleukin-1 receptor-related protein 2 | AcPL | c-Jun N-terminal kinase | IL-1ra | NFκB | JAK-STAT | paraventricular hypothalamic nucleus | TNFRII | CVOs | IKK-αβγ | cyclooxygenase | prostaglandin E receptors 1–4 | IL-1RI | MAPK | tyrosine phosphatase-2 | P-450 | TIRAP | peptidoglycan | NOS | IL-18R | interleukin-18 receptor accessory protein-like | CRF | cerebrospinal fluid | AVP | IL-1RAPL | evolutionary conserved signalling intermediate in Toll pathways | nuclear transcription factor-kappa B | subfornical organ | mRNA | inducible nitric oxide synthase | corticotropin-releasing factor | signal transducers and activators of transcription | interleukin-1 receptor | intravenous | CSF | TLR | interleukin | JAKs | VMPO | IFNs | preoptic area of the hypothalamus | PGE2 | interferon regulatory factor 3 | macrophage inflammatory protein-1 beta | SOCS | TIGIRR | toll interacting protein | soluble interleukin-6 receptor | arginine vasopressin | mPGES | RIP | prostaglandins | toll/interleukin-1 receptor domain-containing adapter protein
Book Chapter
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