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1. Full Text The role of ubiquitin in NF-κB regulatory pathways
by Skaug, Brian and Jiang, Xiaomo and Chen, Zhijian J
Annual review of biochemistry, ISSN 0066-4154, 2009, Volume 78, Issue 1, pp. 769 - 796
IKK | TAK1 | Deubiquitination | Apoptosis
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2. Full Text Indirubin attenuates IL-17A-induced CCL20 expression and production in keratinocytes through repressing TAK1 signaling pathway
by Zhao, Jingxia and Xie, Xiangjiang and Di, Tingting and Liu, Yu and Qi, Cong and Chen, Zhaoxia and Li, Ping and Wang, Yan
International immunopharmacology, ISSN 1567-5769, 05/2021, Volume 94
IL-17A | Indirubin | TAK1 | Psoriasis | Keratinocytes | CCl20
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3. Full Text Author Correction: Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway
by Singh, Kanika and Gupta, Ankit and Sarkar, Ashish and Gupta, Ishita and Rana, Santanu and Sarkar, Sagartirtha and Khan, Sameena
Scientific reports, ISSN 2045-2322, 06/2020, Volume 10, Issue 1, pp. 10662 - 10662
Arginyltransferase | TAK1 protein | Fibrosis | Hypertrophy | Index Medicus
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4. Full Text Transforming growth factor-b-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis
by Blyszczuk, Przemyslaw and Müller-Edenborn, Björn and Valenta, Tomas and Osto, Elena and Stellato, Mara and Behnke, Silvia and Glatz, Katharina and Basler, Konrad and Lüscher, Thomas F and Distler, Oliver and Eriksson, Urs and Kania, Gabriela
European heart journal, ISSN 0195-668X, 05/2017, Volume 38, Issue 18, pp. 1413 - 1425
Cardiac fibroblasts | Experimental autoimmune myocarditis | CD133 inflammatory progenitor | Myofibroblast TGF-β signalling | Wnt-TAK1 signalling
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5. Full Text Synthesis and anti-tumor activity of imidazopyrazines as TAK1 inhibitors
by Kang, Seok Jong and Lee, Jung Wuk and Chung, Shin Hyuck and Jang, Sun Young and Choi, Jaeyul and Suh, Kwee Hyun and Kim, Young Hoon and Ham, Young Jin and Min, Kyung Hoon
European journal of medicinal chemistry, ISSN 0223-5234, 02/2019, Volume 163, pp. 660 - 670
TAK1 | Imidazopyrazine | Colon cancer | Index Medicus
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6. Full Text TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades
by Scarneo, Scott A and Yang, Kelly W and Roques, Jose R and Dai, Alanna and Eibschutz, Liesl S and Hughes, Philip and Haystead, Timothy A.J
Oncotarget, ISSN 1949-2553, 05/2020, Volume 11, Issue 21, pp. 1961 - 1970
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7. Full Text Ubiquitination in signaling to and activation of IKK
by Chen, Zhijian J
Immunological reviews, ISSN 0105-2896, 03/2012, Volume 246, Issue 1, pp. 95 - 106
RIG‐I | IKK | MAVS | NF‐κB | TAK1 | ubiquitin | Ubiquitin | NF-κB | RIG-I | Life Sciences & Biomedicine | Immunology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Ubiquitination | Animals | I-kappa B Kinase - metabolism | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Humans | Proteins | Enzymes | Lysine | Ligases | Physiological aspects | Binding proteins | Protein binding | TRAF6 protein | TAK1 protein | Regulatory subunits | Inflammation | IKK protein | Signal transduction | NF- Kappa B protein | Tumor necrosis factor | ubiquitination | I Kappa B kinase | Ubiquitin-protein ligase | Index Medicus
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8. Full Text Grass carp (Ctenopharyngodon idella) TRAF6 and TAK1: Molecular cloning andexpression analysis after Ichthyophthirius multifiliis infection
by Zhao, Fei and Li, Yan-Wei and Pan, Hou-Jun and Wu, Shu-Qin and Shi, Cun-Bin and Luo, Xiao-Chun and Li, An-Xing
Fish & shellfish immunology, ISSN 1050-4648, 06/2013, Volume 34, Issue 6, pp. 1514 - 1523
Ctenopharyngodon idella | Ichthyophthirius multifiliis | TAK1 | TRAF6
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9. Full Text Heat-Killed Lactobacillus brevis Enhances Phagocytic Activity and Generates Immune-Stimulatory Effects through Activating the TAK1 Pathway
by Minju Jeong and and Jae Hwan Kim and Ji Su Lee and Shin Dal Kang and Sangmin Shim and Moon Young Jung and Hee Yang and Sanguine Byun and Ki Won Lee
Journal of microbiology and biotechnology, ISSN 1017-7825, 09/2020, Volume 30, Issue 9, pp. 1395 - 1403
phagocytosis | immune stimulation | TAK1 | Lactobacillus brevis | probiotics
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10. Full Text Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
by Licchesi, Julien D F and Wilkinson, Keith D and Odenwaelder, Peter and Barford, David and Reyes-Turcu, Francisca and Komander, David
EMBO reports, ISSN 1469-221X, 05/2009, Volume 10, Issue 5, pp. 466 - 473
TAK1/IKK/NEMO/NF‐κB | ubiquitin binding domain | NF‐κB signalling | ubiquitin linkage | deubiquitinase | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proteins | Signal transduction | Cellular biology | Molecular biology | Binding sites | Index Medicus | NF-κB | TAK1 | NF-κB signalling | IKK | NEMO | Scientific Report
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11. Full Text TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers
by Freudlsperger, C and Bian, Y and Contag Wise, S and Burnett, J and Coupar, J and Yang, X and Chen, Z and Van Waes, C
Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 12, pp. 1549 - 1559
celastrol | TGF-b TAK1 | head and neck cancer | NF-kB | SMAD7 | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcription Factor RelA - physiology | Cell Proliferation | Neoplasm Invasiveness | Carcinoma, Squamous Cell - pathology | Humans | Transforming Growth Factor beta - physiology | Head and Neck Neoplasms - pathology | Carcinoma, Squamous Cell - etiology | Smad7 Protein - physiology | Squamous Cell Carcinoma of Head and Neck | Head and Neck Neoplasms - etiology | NF-kappa B - physiology | Cell Line, Tumor | MAP Kinase Kinase Kinases - physiology | Signal Transduction - physiology | Cell Movement | Index Medicus | NF-κB | TGF-β | TAK1
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12. Full Text Tak1 in the astrocytes of mediobasal hypothalamus regulates anxiety‐like behavior in mice
by Zhao, Faming and Zhang, Tingting and Shen, Qing and Yin, Kaili and Wang, Yu and Zhang, Guo
Glia, ISSN 0894-1491, 03/2021, Volume 69, Issue 3, pp. 609 - 618
anxiety | Tak1 | astrocyte | mediobasal hypothalamus | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Astrocytes | Anxieties | TAK1 protein | Anxiety disorders | Anxiety | Hypothalamus | Kinases | Growth factors | Locomotor activity | Index Medicus
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13. Full Text Exercise ameliorates insulin resistance via regulating TGFβ‐activated kinase 1 (TAK1)‐mediated insulin signaling in liver of high‐fat diet‐induced obese rats
by Zhang, Yong and Wan, Jianyong and Xu, Zhen and Hua, Tianmiao and Sun, Qingyan
Journal of cellular physiology, ISSN 0021-9541, 05/2019, Volume 234, Issue 5, pp. 7467 - 7474
TGFβ‐activated kinase 1 (TAK1) phosphorylation | insulin signaling | insulin resistance (IR) | exercise training | TGFβ-activated kinase 1 (TAK1) phosphorylation | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation - physiology | Liver - metabolism | Diet, High-Fat - adverse effects | Rats | Male | Obesity - physiopathology | TNF Receptor-Associated Factor 3 - metabolism | MAP Kinase Kinase Kinases - metabolism | Intra-Abdominal Fat - metabolism | Physical Conditioning, Animal - physiology | Rats, Sprague-Dawley | Obesity - metabolism | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Insulin Resistance - physiology | Signal Transduction - physiology | Ubiquitin-Specific Proteases - metabolism | Transforming Growth Factor beta - metabolism | Ubiquitin | Physical exercise | Phosphorylation | Regulators | Body fat | TAK1 protein | Glycogen | Liver | Body weight | Lipids | AKT protein | Kinases | Insulin | Substrates | High fat diet | USP18 protein | Proteins | Signaling | Sensitivity | Insulin receptor substrate 1 | Diet | Rodents | Insulin resistance | Index Medicus
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14. Full Text LRRC62 attenuates Toll-like receptor signaling by deubiquitinating TAK1 via CYLD
by Zhang, Jindong and Ou, Jiayu and Wan, Xiaoye
Experimental cell research, ISSN 0014-4827, 10/2019, Volume 383, Issue 1, pp. 111497 - 111497
NF-κB | LRRC62 | TAK1 | K63-linked ubiquitination | Index Medicus
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15. Full Text Dusp14 protects against hepatic ischaemia–reperfusion injury via Tak1 suppression
by Wang, Xiaozhan and Mao, Wenzhe and Fang, Chun and Tian, Song and Zhu, Xueyong and Yang, Ling and