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1. Full Text Neuroprotective effect of tanshinone IIA-incubated mesenchymal stem cells on Aβ 25-35 -induced neuroinflammation
by Huang, Nanqu and Li, Yuanyuan and Zhou, Yongjian and Zhou, Yanjun and Feng, Fei and Shi, Shangpeng and Ba, Zhisheng and Luo, Yong
Behavioural Brain Research, ISSN 0166-4328, 06/2019, Volume 365, pp. 48 - 55
Mesenchymal stem cell transplantation can regulate neuroinflammation and treat Alzheimer's disease (AD), but its effect is attenuated by in vitro expansion. To... 
Mesenchymal stem cell | Tanshinone IIA | Neuroinflammation | Alzheimer's disease
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2. Full Text Neuroprotective effect of tanshinone IIA-incubated mesenchymal stem cells on Aβ25-35-induced neuroinflammation
by Huang, Nanqu and Li, Yuanyuan and Zhou, Yanjun and Zhou, Yongjian and Feng, Fei and Shi, Shangpeng and Ba, Zhisheng and Luo, Yong
Behavioural Brain Research, ISSN 0166-4328, 06/2019, Volume 365, pp. 48 - 55
Mesenchymal stem cell transplantation can regulate neuroinflammation and treat Alzheimer's disease (AD), but its effect is attenuated by in vitro expansion. To... 
Mesenchymal stem cell | Tanshinone IIA | Neuroinflammation | Alzheimer’s disease | Index Medicus
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3. Full Text Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury
by Ding, CY and Chen, HJ and Liang, B and Jiao, MK and Liang, G and Zhang, A
CHEMICAL SCIENCE, ISSN 2041-6520, 05/2019, Volume 10, Issue 17, pp. 4667 - 4672
Acute lung injury (ALI) is an inflammatory disease with no effective pharmacological treatment. The therapeutic potential of the anti-inflammatory natural... 
ABSORPTION | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | RESPIRATORY-DISTRESS-SYNDROME | TANSHINONE-IIA
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4. Full Text Tanshinone MA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1
by Shan, Hongli and Li, Xuelian and Pan, Zhenwei and Zhang, Li and Cai, Benzhi and Zhang, Yong and Xu, Chaoqian and Chu, Wenfeng and Qiao, Guofen and Li, Baoxin and Lu, Yanjie and Yang, Baofeng
British Journal of Pharmacology, ISSN 0007-1188, 2009, Volume 158, Issue 5, pp. 1227 - 1235
MicroRNA-1 | Tanshinone IIa | Ischaemic arrhythmia | Sudden cardiac death | Kir2.1 | SRF
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5. Full Text Site-selective Csp3-H aryloxylation of natural product Tanshinone IIA and its analogues
by Liang, Bing and Liang, Gaolin and Yu, Shujuan and Li, Jie and Wang, Fan and Zhang, Ao and Ding, Chunyong
Tetrahedron Letters, ISSN 0040-4039, 05/2017, Volume 58, Issue 19, pp. 1822 - 1825
A novel catalyst-free Csp -H aryloxylation approach allowing for rapid installation of a wide range of aryloxyl groups regioselectively at the C-4 position of... 
Natural product | Tanshinone IIA | Chemical modification | C-H activation | Aryloxylation
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6. Full Text Tanshinone IIA protects against cardiac hypertrophy via inhibiting cal-cineurin/Nfatc3 pathway
by Tan, Xueying and Li, Jianping and Wang, Xinyue and Chen, Nan and Cai, Benzhi and Wang, Gang and Shan, Hongli and Dong, Deli and Liu, Yanju and Li, Xingda and Yang, Fan and Li, Xin and Zhang, Peng and Li, Xueqi and Yang, Baofeng and Lu, Yanjie
International Journal of Biological Sciences, ISSN 1449-2288, 2011, Volume 7, Issue 3, pp. 383 - 389
Cardiac hypertrophy | NFATc3 | Tanshinone IIA | Isoproterenol | Calcineurin
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7. Full Text Combined treatment of melatonin and sodium tanshinone IIA sulfonate reduced the neurological and cardiovascular toxicity induced by deltamethrin in zebrafish
by Li, Meng and Zhang, Ti and Jia, YiQing and Sun, YuMeng and Zhang, ShaoZhi and Mi, Ping and Feng, ZeYang and Zhao, Xin and Chen, DongYan and Feng, XiZeng
Chemosphere, ISSN 0045-6535, 03/2020, Volume 243, p. 125373
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8. Full Text Sodium Tanshinone IIA sulfonate improves post-ischemic angiogenesis in hyperglycemia
by Chen, Lingdan and He, Wenjun and Peng, Bin and Yuan, Mingjie and Wang, Tao and Wang, Neng and Wang, Jian and Lu, Wenju
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2019, Volume 520, Issue 3, pp. 580 - 585
Diabetes is a strong risk factor of peripheral arterial disease (PAD), and also leads to impaired perfusion recovery in the ischemic limb, which eventually... 
Sodium Tanshinone IIA sulfonate | Angiogenesis | Reactive oxygen species | Diabetes | Peripheral Arterial Disease
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9. Full Text Tanshinone ⅡA inhibits homocysteine-induced proliferation of vascular smooth muscle cells via miR-145/CD40 signaling
by Li, Yao and Chen, Fenyan and Guo, Ren and Jia, Sujie and Li, Wenqun and Zhang, Bikui
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019
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10. Full Text Tanshinone IIA attenuates high glucose induced human VSMC proliferation and migration through miR-21-5p-mediated tropomyosin 1 downregulation
by Jia, Shan and Ma, Wei-dong and Zhang, Yan and Zhang, Chun-yan and Yao, Zhi-hui and Quan, Xiao-hui and Guo, Xuan and Wang, Cong-xia
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 11/2019, Volume 677, p. 108154
The proliferation and migration of vascular smooth muscle cells (VSMCs) play important roles in the development and progression of diabetes-related vascular... 
microRNAs | Tanshinone IIA | Tropomyosin 1 | Vascular smooth muscle cells | High glucose
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11. Full Text Tanshinone IIA protects lens epithelial cells from H2O 2‐induced injury by upregulation of lncRNA ANRIL
by Qi, Defeng and Wang, Mingming and Zhang, Duzhen and Li, Haihui
Journal of Cellular Physiology, ISSN 0021-9541, 09/2019, Volume 234, Issue 9, pp. 15420 - 15428
Tanshinone IIA is a lipophilic diterpene extracted from the Salvia miltiorrhiza bunge, possessing antiapoptotic and antioxidant activities. The purpose of this... 
lncRNA ANRIL | NF‐κB signaling | tanshinone IIA | cataract | hydrogen peroxide | NF-κB signaling
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12. Full Text Tanshinone IIA contributes to the pathogenesis of endometriosis via renin angiotensin system by regulating the dorsal root ganglion axon sprouting
by Chen, Zhen-zhen and Gong, Xin
Life Sciences, ISSN 0024-3205, 11/2019, p. 117085
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13. Full Text Effects of the combination of tanshinone IIA and puerarin on cardiac function and inflammatory response in myocardial ischemia mice
by Gao, Shan and Li, Lan and Li, Lingyan and Ni, Jingyu and Guo, Rui and Mao, Jingyuan and Fan, Guanwei
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 12/2019, Volume 137, pp. 59 - 70
Ventricular remodeling is a major pathological process of normal heart failure. With the aging of society, poor diet control, social, psychological and other... 
Ventricar remodeling | Tanshinone IIA | Myocardial ischemia | Inflammatory cells | Puerarin | Compatibility
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14. Full Text PEG-amino acid-przewaquinone a conjugations: Synthesis, physicochemical properties and protective effect in a rat model of brain ischemia-reperfusion
by Wang, Minghui and Niu, Ao and Gong, Zhibo and Xu, Zhengwen and Li, Lili and Li, Bo and Wang, Jinxin
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2020, Volume 30, Issue 1, p. 126780
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15. Full Text Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases
by Saraiva, Cláudia and Praça, Catarina and Ferreira, Raquel and Ferreira, Lino and Santos, Tiago and Bernardino, Liliana
Journal of Controlled Release, ISSN 0168-3659, 08/2016, Volume 235, pp. 34 - 47
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating blood. The BBB's unique and protective features control brain... 
Nanoparticles | Brain repair | Stroke | Parkinson's disease | Alzheimer's disease | Blood–brain barrier | Blood-brain barrier | P-GLYCOPROTEIN FUNCTION | GOLD NANOPARTICLES | ALZHEIMERS-DISEASE | REPERFUSION INJURY | CHEMISTRY, MULTIDISCIPLINARY | TANSHINONE IIA NANOPARTICLES | TIGHT JUNCTIONS | CIRCUMVENTRICULAR ORGANS | POLYMERIC NANOPARTICLES | IN-VITRO MODEL | PHARMACOLOGY & PHARMACY | PARKINSONS-DISEASE | Brain - metabolism | Animals | Biological Transport | Nanoparticles - therapeutic use | Humans | Nanoparticles - administration & dosage | Neurodegenerative Diseases - metabolism | Neurodegenerative Diseases - drug therapy | Drug Delivery Systems | Drugs | Drug delivery systems | Nervous system diseases | Vehicles
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16. Full Text Neuroprotective effect of tanshinone IIA-incubated mesenchymal stem cells on A beta(25-35)-induced neuroinflammation
by Huang, NQ and Li, YY and Zhou, YJ and Feng, F and Shi, SP and Ba, ZS and Luo, Y
BEHAVIOURAL BRAIN RESEARCH, ISSN 0166-4328, 06/2019, Volume 365, pp. 48 - 55
Mesenchymal stem cell transplantation can regulate neuroinflammation and treat Alzheimer's disease (AD), but its effect is attenuated by in vitro expansion. To... 
Mesenchymal stem cell | Tanshinone IIA | ALZHEIMERS-DISEASE | Neuroinflammation | BEHAVIORAL SCIENCES | Alzheimer's disease | NEUROSCIENCES
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17. Full Text Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1–42-induced apoptosis due to prevention of endoplasmic reticulum stress
by Yang, Weina and Yang, Xiaohua and Zhang, Jianshui and Shi, Lili and Ji, Shengfeng and Zhai, Wanying and Zong, Hangfan and Qian, Yihua
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 02/2019, Volume 107, pp. 82 - 91
Endoplasmic reticulum (ER) stress caused by β-amyloid protein (Aβ) may play an important role in the pathogenesis of Alzheimer disease (AD). Our previous data... 
β-amyloid protein | Tanshinone IIA | Alzheimer disease | Endoplasmic reticulum stress | Apoptosis | Index Medicus
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18. Full Text Tanshinone IIA ameliorates oxaliplatin-induced neurotoxicity via mitochondrial protection and autophagy promotion
by Cheng, Weiting and Xiang, Wei and Wang, Shan and Xu, Kai
American Journal of Translational Research, ISSN 1943-8141, 2019, Volume 11, Issue 5, pp. 3140 - 3149
Peripheral neurotoxicity is a common adverse reaction in cancer patients undergoing chemotherapy. The neuropathologic changes were partly associated with... 
Tanshinone IIA | Chemotherapy | Neurotoxicity | Autophagy
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19. Full Text Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis
by Jiang, Ying and Hu, Feifei and Li, Qiao and Shen, Chen and Yang, Ji and Li, Ming
International Immunopharmacology, ISSN 1567-5769, 11/2019, p. 105968
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20. Full Text Tanshinone IIA attenuates silica-induced pulmonary fibrosis via inhibition of TGF-β1-Smad signaling pathway
by Feng, Feifei and Li, Nannan and Cheng, Peng and Zhang, Huanan and Wang, Hui and Wang, Yongbin and Wang, Wei
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 01/2020, Volume 121, p. 109586
Transforming growth factor-β 1 (TGF-β1) is a key mediator in fibrogenesis, and is upregulated and activated in fibrotic diseases. The exact role of TGF-β1-Smad... 
Tanshinone IIA | Smad | Pulmonary fibrosis | Silicosis | Transforming growth factor-beta 1
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