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Science, ISSN 0036-8075, 2/2009, Volume 323, Issue 5918, pp. 1205 - 1208
Journal Article
Science, ISSN 0036-8075, 2/2009, Volume 323, Issue 5918, pp. 1208 - 1211
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 30, pp. 13318 - 13323
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 12, pp. E2466 - E2475
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 04/2015, Volume 11, Issue 4, pp. 685 - 700
OPTN (optineurin) is an autophagy receptor and mutations in the OPTN gene result in familial glaucoma (E50K) and amyotrophic lateral sclerosis (ALS) (E478G).... 
CCD, coiled-coil domain | FT, filter-trap assay | Ab, antibody | E | TUBA, alpha tubulin | Ub, ubiquitin B/C/D | WB, western blot | UbBD, ubiquitin-binding domain | UPS, ubiquitin-proteasome system | ALS, amyotrophic lateral sclerosis | BafA1, bafilomycin A | PBS, phosphate-buffered saline | huntingtin | dominant-negative | mHTT, mutant huntingtin | autophagy | f | K63, lysine 63 | WT, wild type | FRET efficiency | IBs, inclusion bodies | MYO6, myosin VI | IP, immunoprecipitation | TARDBP/TDP-43 | 1 | HD, Huntington disease | LIR, LC3-interacting region | K48, lysine 48 | optineurin | TARDBP/TDP-43, TAR DNA-binding protein | PFA, paraformaldehyde | TBK1, TANK-binding kinase 1 | OPTN, optineurin | Optineurin | Dominant-negative | Huntingtin | Autophagy | NEURODEGENERATIVE DISEASE | AMYOTROPHIC-LATERAL-SCLEROSIS | FRONTOTEMPORAL LOBAR DEGENERATION | SELECTIVE AUTOPHAGY | CELL BIOLOGY | TRANSFERRIN RECEPTOR | GLAUCOMA | HUNTINGTONS-DISEASE | MYOSIN-VI | GOLGI-COMPLEX | Protein Binding - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Mutant Proteins - genetics | Transcription Factor TFIIIA - genetics | Cytoplasm - metabolism | Mutant Proteins - metabolism | Autophagy - physiology | Mutation - genetics | Transcription Factor TFIIIA - metabolism | Protein Folding | DNA-Binding Proteins - metabolism | Animals | Eye Proteins - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Cytoplasm - genetics | Mice | Autophagy - genetics | Eye Proteins - genetics | Binding Sites
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2010, Volume 30, Issue 22, pp. 7729 - 7739
Inclusion body myopathy associated with Paget's disease of bone and frontotemporal dementia (IBMPFD) is a dominantly inherited degenerative disorder caused by... 
VALOSIN-CONTAINING PROTEIN | UBIQUITIN-PROTEASOME SYSTEM | INCLUSION-BODY MYOPATHY | MESSENGER-RNA | FRONTOTEMPORAL DEMENTIA | TARDBP MUTATIONS | AMYOTROPHIC-LATERAL-SCLEROSIS | BINDING PROTEIN | NEUROSCIENCES | PAGET-DISEASE | VCP DISEASE | Index Medicus
Journal Article
Journal Article