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Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 3, p. e0193867
.... Since iron and cholesterol accumulation impact on neurodegener-ative disease, the associated gene variants are appealing candidate targets for risk and disease progression assessment... 
HFE MUTATIONS | OXIDATIVE STRESS | VENOUS DISEASE | VASCULAR DEMENTIA | ONSET ALZHEIMERS-DISEASE | OLDER SUBJECTS | BASAL GANGLIA | MULTIDISCIPLINARY SCIENCES | HEMOCHROMATOSIS GENE | AMYLOID PRECURSOR PROTEIN | APOLIPOPROTEIN-E | Genetic Predisposition to Disease | Dementia, Vascular - genetics | Gene Expression Regulation - genetics | Humans | Risk Factors | Male | Mental Status and Dementia Tests | Iron - metabolism | Transferrin - genetics | Hemochromatosis Protein - genetics | Apolipoproteins E - genetics | Alleles | Aged, 80 and over | Hepcidins - genetics | Cation Transport Proteins - genetics | Cognitive Dysfunction - genetics | Female | Aged | Polymorphism, Single Nucleotide | Alzheimer Disease - genetics | Homeostasis - genetics | Allelomorphism | Analysis | Homeostasis | Genetic aspects | Research | Cognition disorders | Single nucleotide polymorphisms | Apolipoproteins | Protein-protein interactions | Brain | Transferrin | Multiple sclerosis | Target recognition | Cognitive ability | Impairment | Biochemistry | Single-nucleotide polymorphism | Risk factors | Proteins | Neurodegeneration | Coding | Surgery | Genetics | Lipid metabolism | Alzheimer's disease | Apolipoprotein E4 | Vascular dementia | Risk analysis | Metabolism | Patients | Thrombosis | Homozygotes | Morphology | Mutation | Hepcidin | Transporter | Geriatrics | Oxidative stress | Laboratories | Genes | Lipids | Iron | Coexistence | Accumulation | Reduction | Apolipoprotein E | Dementia disorders | Hemochromatosis | Therapeutic applications | Health risks | Risk reduction | Pharmacology | Cholesterol | Medicine | Brain research | HFE protein | Molecular biology | Alzheimers disease | Apoptosis
Journal Article
PLoS biology, ISSN 1545-7885, 2018, Volume 16, Issue 3, p. e2004328
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2017, Volume 214, Issue 3, pp. 793 - 814
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1 - 11
.... A common approach is to infer signaling activity of pathways from gene expression. However, mapping gene expression to pathway components disregards the effect of post... 
PATHWAYS | ENCYCLOPEDIA | SIGNATURES | DATABASE | MULTIDISCIPLINARY SCIENCES | TARGETS | MAP | GAIN | PI3K/AKT | Downstream effects | Genes | Mapping | Perturbation | Gene expression | Kinases | Progeny | Signal transduction | Signaling | Pathways | Post-translation | Tumor suppressor genes | Aberration | Mutation | Gene mapping | Cancer
Journal Article