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Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 19, pp. 15635 - 15647
The RNA-binding proteins TDP-43 and FUS form abnormal cytoplasmic aggregates in affected tissues of patients with amyotrophic lateral sclerosis and... 
VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALS | FUS/TLS | TARGETS | AMYOTROPHIC-LATERAL-SCLEROSIS | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | STRESS GRANULES | DROSOPHILA | ENDOTHELIAL GROWTH-FACTOR | TATA-Binding Protein Associated Factors - metabolism | Protein Biosynthesis | Immunoprecipitation | Oligonucleotide Array Sequence Analysis | Nucleotide Motifs - genetics | Vesicular Transport Proteins - metabolism | Humans | 3' Untranslated Regions - genetics | Cytoplasm - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | RNA Interference | Motor Neurons - cytology | Cytoplasm - genetics | Cell Line | RNA, Messenger - genetics | Vesicular Transport Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | RNA-Binding Protein FUS - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | RNA Stability | Reverse Transcriptase Polymerase Chain Reaction | TATA-Binding Protein Associated Factors - genetics | Blotting, Western | Motor Neurons - metabolism | Animals | Protein Binding | Mice | Mutation | Molecular Bases of Disease | Neurodegenerative Diseases | RNA-Protein Interaction | RIP-chip | FUS | TDP-43 | RNA Binding Protein | RNA Metabolism | RNA Processing | Post-transcriptional Regulation
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36323
Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical... 
TARGET | RELATIVE QUANTIFICATION | RT-PCR | LIVER-DISEASES | MULTIDISCIPLINARY SCIENCES | GUIDELINES | QUANTITATIVE PCR | INJURY | NORMALIZATION | HOUSEKEEPING GENES | EXPRESSION | Liver - pathology | Gene Expression - drug effects | Acetaminophen - toxicity | Liver - metabolism | RNA, Messenger - genetics | Rats | Gene Expression Profiling | Glyceraldehyde-3-Phosphate Dehydrogenases - genetics | Chemical and Drug Induced Liver Injury - genetics | Carbon Tetrachloride - toxicity | Actins - genetics | Animals | Thioacetamide - toxicity | Liver - drug effects | RNA, Small Nuclear - genetics | Reverse Transcriptase Polymerase Chain Reaction - methods | MicroRNAs - genetics | Chemical and Drug Induced Liver Injury - etiology | Galactosamine - toxicity | RNA | Acetaminophen | Genes | Liver | Carbon tetrachloride | Genetic aspects | Genetic translation | Regulators | Animal models | Transcription | Glyceraldehyde | Identification | Ovarian cancer | Accuracy | Actin | Gangrene | Physiology | Mathematical models | Hepatotoxicity | Neutrophils | MiRNA | Gene expression | Real time | Carbon | Polymerase chain reaction | Studies | Thioacetamide | Software packages | Algorithms | D-Galactosamine | Acids | Ribonucleic acids | MicroRNAs | rRNA 5S | Biomarkers | Control stability | rRNA 18S | Methods | mRNA stability | Translation | software | Data processing | mRNA | Computer programs | hepatotoxicity | miRNA | Models
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 2013, Volume 4
microRNA miR-221 is frequently over-expressed in a variety of human neoplasms. Aim of this study was to identify new miR-221 gene targets to improve our... 
Sylamer | microRNA | Gene targets | Microarray | miR-221 | gene targets
Journal Article
by Wang, LB and Wang, B and Liu, JK and Quan, ZX
MOLECULAR MEDICINE REPORTS, ISSN 1791-2997, 04/2019, Volume 19, Issue 4, pp. 3021 - 3034
Spinal cord injury (SCI) results from trauma and predominantly affects the young male population. SCI imposes major and permanent life changes, and is... 
MEDICINE, RESEARCH & EXPERIMENTAL | ceRNA | APOPTOSIS | autophagy | lncRNA | LNCRNAS | AKT | IDENTIFICATION | CANCER | PI3K | ONCOLOGY | GENES | SCI | mTOR | DEGRADATION | TARGETS | BRAIN
Journal Article
NATURE REVIEWS GENETICS, ISSN 1471-0056, 04/2012, Volume 13, Issue 4, pp. 271 - 282
MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways. These small non-coding RNAs bind to target sequences in mRNAs, typically... 
MESSENGER-RNAS | POSTTRANSCRIPTIONAL REGULATION | TRANSLATIONAL REPRESSION | CAENORHABDITIS-ELEGANS | CODING REGIONS | WIDE IDENTIFICATION | GENETICS & HEREDITY | MIRNA TARGETS | RING FINGER | BINDING PROTEIN HUR | SYSTEMATIC IDENTIFICATION
Journal Article
Frontiers in genetics, ISSN 1664-8021, 2013, Volume 4, p. 64
microRNA miR-221 is frequently over-expressed in a variety of human neoplasms. Aim of this study was to identify new miR-221 gene targets to improve our... 
Journal Article
NATURE, ISSN 0028-0836, 01/2011, Volume 469, Issue 7328, pp. 97 - U114
Post-transcriptional gene regulation frequently occurs through elements in mRNA 3' untranslated regions (UTRs)(1,2). Although crucial roles for 3'UTR-mediated... 
3' UNTRANSLATED REGIONS | MESSENGER-RNAS | COMPLEX | SEQUENCES | DATABASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | POLYADENYLATION | TARGETS | C-ELEGANS | MICRORNAS
Journal Article
by Gong, J and Liu, W and Zhang, JY and Miao, XP and Guo, AY
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 01/2015, Volume 43, Issue D1, pp. D181 - D186
Long non-coding RNAs (lncRNAs) play key roles in various cellular contexts and diseases by diverse mechanisms. With the rapid growth of identified lncRNAs and... 
MESSENGER-RNAS | POLYMORPHISMS | LONG NONCODING RNA | GENE | TARGET SITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE-ASSOCIATED SNPS | DIFFERENTIATION | IDENTIFICATION | GENOME | RESOURCE
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 6, pp. 1133 - 1146
MicroRNAs are small noncoding RNAs that serve as posttranscriptional regulators of gene expression in higher eukaryotes. Their widespread and important role in... 
TARGET | ENCODES | NERVOUS-SYSTEM | MESSENGER-RNAS | CAENORHABDITIS-ELEGANS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-ELEGANS | LET-7 | IDENTIFICATION | DROSOPHILA | CELL BIOLOGY
Journal Article
Cell, ISSN 0092-8674, 2009, Volume 136, Issue 4, pp. 642 - 655
Journal Article