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Human Molecular Genetics, ISSN 0964-6906, 10/2004, Volume 13, Issue 19, pp. 2263 - 2278
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2016, Volume 22, Issue 22, pp. 5434 - 5442
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2016, Volume 29, Issue 4, pp. 464 - 476
The epigenome is a key determinant of transcriptional output. Perturbations within the epigenome are thought to be a key feature of many, perhaps all cancers,... 
targeted therapy | epigenome | histone modification | chromatin | Cancer | Histone modification | Chromatin | Epigenome | Targeted therapy | SELECTIVE-INHIBITION | THERAPEUTIC STRATEGY | ONCOLOGY | LYSINE 27 METHYLATION | HISTONE H3 | DROSOPHILA-TRITHORAX | 11Q23 TRANSLOCATIONS | CHROMATIN MODIFICATIONS | EMERGING MECHANISMS | TRANSCRIPTIONAL REGULATION | SOMATIC MUTATIONS | CELL BIOLOGY | Transcription, Genetic - drug effects | Humans | Gene Expression Regulation, Neoplastic | Neoplasms - prevention & control | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Neoplasms - therapy | Histone Code - drug effects | Neoplasms - genetics | Protein Processing, Post-Translational - drug effects | Cell Transformation, Neoplastic - genetics | Antineoplastic Agents - pharmacokinetics | Epigenesis, Genetic - drug effects | Chromatin - drug effects | Epigenomics | Oncogene Proteins - metabolism | Therapies, Investigational | Clinical Trials as Topic | DNA, Neoplasm - drug effects | Drug Resistance, Neoplasm - genetics | Animals | Epigenesis, Genetic - genetics | Chromosome Aberrations | Histone Deacetylase Inhibitors - therapeutic use | Mice | Models, Genetic | DNA, Neoplasm - genetics | Histones - metabolism | Mutation | Chromatin - genetics | DNA Methylation - drug effects | Drug Resistance, Neoplasm - drug effects | Epigenetic inheritance | Development and progression | Genetic aspects
Journal Article