X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1142) 1142
Publication (162) 162
Book Chapter (23) 23
Book Review (23) 23
Conference Proceeding (4) 4
Book / eBook (2) 2
Dissertation (1) 1
Government Document (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (696) 696
index medicus (664) 664
animals (570) 570
cancer (356) 356
gene targeting (330) 330
mice (314) 314
oncology (310) 310
biochemistry & molecular biology (257) 257
cell biology (254) 254
apoptosis (230) 230
expression (225) 225
gene expression (221) 221
proteins (214) 214
research (197) 197
cell line, tumor (172) 172
genetic aspects (161) 161
tumors (161) 161
female (144) 144
c-myc (140) 140
health aspects (131) 131
cell proliferation (127) 127
care and treatment (124) 124
signal transduction (124) 124
article (121) 121
male (113) 113
metastasis (110) 110
in-vivo (107) 107
biotechnology & applied microbiology (106) 106
cell cycle (105) 105
genetics & heredity (105) 105
gene targeting - methods (104) 104
microrna (103) 103
gene expression regulation, neoplastic (102) 102
genes (102) 102
medicine, research & experimental (101) 101
stem cells (101) 101
review (99) 99
mutation (95) 95
micrornas - genetics (94) 94
analysis (92) 92
kinases (92) 92
pharmacology & pharmacy (91) 91
physiological aspects (91) 91
multidisciplinary sciences (87) 87
development and progression (86) 86
down-regulation (85) 85
biology (83) 83
cancer therapies (80) 80
gene-expression (78) 78
medicine (76) 76
research article (76) 76
chemotherapy (75) 75
breast cancer (74) 74
cell growth (74) 74
antineoplastic agents - pharmacology (73) 73
cells (73) 73
breast-cancer (71) 71
molecular sequence data (71) 71
proliferation (71) 71
micrornas (70) 70
rna interference (70) 70
activation (69) 69
rodents (69) 69
growth (68) 68
neoplasms - genetics (68) 68
inhibition (67) 67
transcription (66) 66
in-vitro (64) 64
mice, transgenic (64) 64
base sequence (63) 63
gene (63) 63
epithelial-mesenchymal transition (61) 61
phosphorylation (61) 61
drug targeting (60) 60
gene therapy (60) 60
gene expression regulation (59) 59
cell line (58) 58
mirna (58) 58
genetics (56) 56
micrornas - metabolism (56) 56
ribonucleic acid--rna (55) 55
transcription factors (55) 55
mice, knockout (54) 54
neoplasms - drug therapy (54) 54
studies (52) 52
dna (51) 51
protein (51) 51
rna (51) 51
stem-cells (51) 51
antineoplastic agents - therapeutic use (50) 50
binding sites (50) 50
deoxyribonucleic acid--dna (50) 50
disease models, animal (50) 50
mice, inbred c57bl (50) 50
transfection (50) 50
chemistry, multidisciplinary (49) 49
genetic therapy - methods (49) 49
protein binding (49) 49
tumor-suppressor (48) 48
drug delivery systems (47) 47
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer Letters, ISSN 0304-3835, 04/2018, Volume 419, pp. 64 - 74
c-Myc amplification-induced cell cycle dysregulation is a common cause for esophageal squamous cell carcinoma (ESCC), but no approved targeted drug is... 
Esophageal squamous cell carcinoma | Targeting c-Myc | JQ1 | Patient derived xenograft | c-Myc amplification | BET BROMODOMAIN INHIBITION | CANCER | SMALL-MOLECULE INHIBITOR | PHARMACOKINETICS | METABOLISM | ONCOLOGY | IN-VIVO | RECURRENCE | TUMOR-GROWTH | EXPRESSION | PROMOTES | Squamous cell carcinoma | Drug approval | Analysis | Esophageal cancer | Stem cells | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2018, Volume 37, Issue 5, p. n/a
Journal Article
Genes and Development, ISSN 0890-9369, 11/2004, Volume 18, Issue 22, pp. 2747 - 2763
Journal Article
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, ISSN 0027-8874, 01/2020, Volume 112, Issue 1, pp. 7 - 9
Journal Article
Journal Article
The FEBS Journal, ISSN 1742-464X, 01/2005, Volume 272, Issue 2, pp. 413 - 421
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 03/2019, Volume 27, Issue 5, pp. 880 - 887
Journal Article
Cancer Research, ISSN 0008-5472, 06/2011, Volume 71, Issue 11, pp. 3912 - 3920
MK-0457 and MK-5108 are novel aurora kinase inhibitors (AKi) leading to G(2)-M cell-cycle arrest. Growth and survival of multiple lymphoma cell lines were... 
APOPTOSIS | TARGETING BCL2 | CANCER CELLS | GENE | RNA | ONCOLOGY | TELOMERASE ACTIVITY | MYELOID-LEUKEMIA | DIFFERENTIATION | MYELOGENOUS LEUKEMIA-CELLS | ALTERED EXPRESSION | Piperazines - administration & dosage | Humans | Histone Deacetylase Inhibitors - administration & dosage | Immunoblotting | Thiazoles - administration & dosage | Genes, myc | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Aurora Kinase A | Lymphoma - metabolism | Lymphoma - drug therapy | Proto-Oncogene Proteins c-myc - biosynthesis | Telomerase - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Hydroxamic Acids - administration & dosage | Lymphoma - pathology | Gene Expression Regulation, Neoplastic - drug effects | Hydroxamic Acids - pharmacology | Cell Survival - drug effects | Cell Growth Processes - drug effects | Cyclohexanecarboxylic Acids - administration & dosage | Lymphoma - genetics | MicroRNAs - biosynthesis | Aurora Kinases | Piperazines - pharmacology | Drug Synergism | Protein Kinase Inhibitors - administration & dosage | Telomerase - biosynthesis | Cyclohexanecarboxylic Acids - pharmacology | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | MicroRNAs - genetics | Protein Kinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-myc - genetics | Thiazoles - pharmacology | Cell Cycle - drug effects
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 135, Issue 1, pp. 2 - 10
The therapeutic index of current anti-cancer chemotherapeutics can be improved by two major mechanisms: 1) developing drugs which are specifically toxic to the... 
Thermal targeting | Cell penetrating peptide | Elastin-like polypeptide | c-Myc | Subcellular localization | NUDE-MICE | THERMALLY-RESPONSIVE POLYPEPTIDES | OVARIAN-CARCINOMA CELLS | SOLID TUMORS | DRUG-DELIVERY | PROTEIN-PROTEIN INTERACTION | CHEMISTRY, MULTIDISCIPLINARY | CANCER-THERAPY | TAT PEPTIDE | ANTIMICROBIAL PEPTIDE | PHARMACOLOGY & PHARMACY | Neoplasms - metabolism | Temperature | Humans | Peptides - pharmacokinetics | Cytoplasm - metabolism | Antineoplastic Agents - administration & dosage | Phase Transition | Drug Carriers - chemistry | Dose-Response Relationship, Drug | Cell Nucleus - metabolism | Peptides - chemical synthesis | Time Factors | Hyperthermia, Induced | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Peptides - chemistry | Peptide Fragments - pharmacokinetics | Recombinant Fusion Proteins - chemical synthesis | Drug Carriers - chemical synthesis | Recombinant Fusion Proteins - chemistry | Neoplasms - drug therapy | Peptide Fragments - chemical synthesis | Peptide Fragments - chemistry | Recombinant Fusion Proteins - pharmacokinetics | Proto-Oncogene Proteins c-myc - antagonists & inhibitors | Cell Line, Tumor | Cell Proliferation - drug effects | Drug Carriers - pharmacokinetics | Cell Nucleus - drug effects | Cytoplasm - drug effects | Microscopy, Fluorescence | Peptides | Elastin | Index Medicus
Journal Article