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Biochemical Journal, ISSN 0264-6021, 02/2015, Volume 465, Issue 3, pp. 471 - 477
Journal Article
CNS and Neurological Disorders - Drug Targets, ISSN 1871-5273, 06/2015, Volume 14, Issue 5, pp. 612 - 626
Journal Article
Current Opinion in Neurobiology, ISSN 0959-4388, 2017, Volume 45, pp. 32 - 38
Highlights • AMPAR function depends to a large extend on AMPAR-interacting proteins. • The composition of AMPAR complexes vastly differs across distinct brain... 
Neurology | Psychiatry | CORNICHON PROTEINS | TRANSMISSION | PHOSPHORYLATION | TRAFFICKING | AUXILIARY SUBUNITS | MUTANT MOUSE | SYNAPTIC PLASTICITY | TARP GAMMA-8 | NEUROSCIENCES | STARGAZIN | TARP-GAMMA-8 | Genetic Variation | Animals | Humans | Brain - physiology | Receptors, AMPA - genetics | Receptors, AMPA - metabolism | Protein Transport | Proteins
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 05/2016, Volume 357, Issue 2, pp. 394 - 414
Members of the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA) subtype of ionotropic glutamate receptors mediate the majority of fast... 
NMDA RECEPTOR | GLUTAMATE | SEIZURE | RATS | PHARMACOLOGY & PHARMACY | RECOGNITION MEMORY | MODEL | ANTAGONISTS | TARP GAMMA-8 | MATCHING-TO-POSITION | REVEALS
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 11/2017, Volume 126, pp. 257 - 270
6-[(1S)-1-[5-(2-hydroxyethoxy)-2-pyridyllpyrazol-3-yl]ethyl]-3H-1,3-benzothiazol-2-one (LY3130481 or CERC-611) is a selective antagonist of AMPA receptors... 
ADJUNCTIVE PERAMPANEL | RANDOMIZED PHASE-III | PHARMACOLOGY & PHARMACY | SLEEP QUALITY | EPILEPSY | TARP GAMMA-8 | NEUROSCIENCES | DISCOVERY | PARTIAL-ONSET SEIZURES
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 08/2019, Volume 57, pp. 185 - 195
Ionotropic glutamate receptors (iGluRs) are tetrameric ion channels that mediate signal transmission at neuronal synapses, where they contribute centrally to... 
AMPA-RECEPTOR | NMDA RECEPTOR | ACTIVATION | TERMINAL DOMAIN | DESENSITIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYNAMICS | POSITIVE ALLOSTERIC MODULATORS | ZINC INHIBITION | TARP GAMMA-8 | BINDING | CELL BIOLOGY | Glutamate | Ion channels | Neurophysiology
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 09/2018, Volume 157, pp. 898 - 908
Journal Article
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, ISSN 1871-5273, 2017, Volume 16, Issue 10, pp. 1099 - 1110
Background & Objective: 6-[(1S)-1-[1-[5-(2-hydroxyethoxy)-2-pyridyl] pyrazol-3-yl] ethyl]-3H-1,3-benzothiazol-2-one (LY3130481 or CERC-611) is a selective... 
GENETIC ABSENCE EPILEPSY | transmembrane | ADJUNCTIVE PERAMPANEL | TARP-g8 | antagonist | TARP GAMMA-8 | NEUROSCIENCES | PARTIAL-ONSET SEIZURES | RODENT MODELS | CERC-611 | anticonvulsant activity | SPIKE-WAVE DISCHARGES | RANDOMIZED PHASE-III | NEURONAL AVALANCHES | PHARMACOLOGY & PHARMACY | RECURRING HIPPOCAMPAL SEIZURES | AMPA receptors | ANTIEPILEPTIC DRUG | LY3130481
Journal Article
The Journal of Physiology, ISSN 0022-3751, 01/2012, Volume 590, Issue 1, pp. 21 - 31
Journal Article