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Cancers, ISSN 2072-6694, 08/2019, Volume 11, Issue 8, p. 1149
Genomic instability could be a beneficial predictor for anthracycline or taxane chemotherapy. We interrogated 188 DNA repair genes in the METABRIC cohort (n =... 
taxane sensitivity | anthracycline resistance | ERCC1
Journal Article
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, ISSN 1055-9965, 6/2018, Volume 27, Issue 6, pp. 680 - 688
Journal Article
Revista Cubana de Farmacia, ISSN 0034-7515, 10/2017, Volume 50, Issue 4
Journal Article
Tetrahedron, ISSN 0040-4020, 07/2013, Volume 69, Issue 27-28, pp. 5685 - 5701
A full account of synthetic efforts toward a lowly oxidized taxane framework is presented. A non-natural taxane, dubbed 'taxadienone', was synthesized as our... 
Cyclase phase | Terpene | Taxadiene | Taxane | Total synthesis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2018, Volume 24, Issue 21, pp. 5261 - 5271
Purpose: Previous human epidermal growth factor receptor-2 (HER2)-derived resistance studies were based on ex vivo models, which could not mirror evolutionary... 
IMPACT | INHIBITION | MANAGEMENT | TRASTUZUMAB | EFFICACY | ONCOLOGY | TAXANE | TUMOR-CELLS | PACLITAXEL
Journal Article
Annals of Oncology, ISSN 0923-7534, 05/2018, Volume 29, Issue 5, pp. 1195 - 1202
Abstract Background Capecitabine is an approved standard therapy for anthracycline- and taxane-pretreated locally advanced or metastatic breast cancer (BC).... 
Phase III | Metastatic breast cancer | Taxane resistant | Vinflunine | Capecitabine | Pretreated
Journal Article
Supportive Care in Cancer, ISSN 0941-4355, 1/2018, Volume 26, Issue 1, pp. 203 - 211
Journal Article
Cancer, ISSN 0008-543X, 03/2017, Volume 123, Issue 5, pp. 759 - 768
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 658 - 665
Purpose: Severe skeletal muscle (SM) loss (sarcopenia) is associated with poor cancer outcomes, including reduced survival and increased toxicity. This study... 
CACHEXIA | METAANALYSIS | SOLID TUMORS | PHARMACOKINETICS | ONCOLOGY | STATISTICS | COLORECTAL-CANCER | DETERMINANT | BODY-MASS INDEX | SARCOPENIA | PACLITAXEL | Body Composition | Prognosis | Follow-Up Studies | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Hospitalization - statistics & numerical data | Tomography, X-Ray Computed | Sarcopenia - chemically induced | Antineoplastic Agents, Phytogenic - administration & dosage | Sarcopenia - etiology | Aged, 80 and over | Adult | Female | Body Surface Area | Taxoids - adverse effects | Antineoplastic Agents, Phytogenic - adverse effects | Body Mass Index | Kaplan-Meier Estimate | Proportional Hazards Models | Sarcopenia - diagnostic imaging | Organ Size | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Adenocarcinoma - complications | Adenocarcinoma - secondary | Breast Neoplasms - complications | Taxoids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Muscle, Skeletal - diagnostic imaging | Breast Neoplasms - mortality | Aged | Muscle, Skeletal - pathology | Specific Gravity | Adenocarcinoma - mortality | Vertebrae | Toxicity | Test procedures | Muscles | Breast cancer | Metastasis | Taxane | Survival | Patients | Skeletal muscle | Metastases | Sarcopenia | Musculoskeletal system | Chemotherapy | Computed tomography | Experimental design | Quality | Cancer | Index Medicus | toxicity | skeletal muscle index | skeletal muscle gauge | metastatic breast cancer | survival | taxane chemotherapy | muscle attenuation | hospitalizations | sarcopenia
Journal Article
中国化学:英文版, ISSN 1001-604X, 2016, Volume 34, Issue 11, pp. 1165 - 1176
7-epi-Taxane has been achieved efficiently in gram scale from natural taxane via inversion of the 7-hydroxyl group simply using Ag20 as catalyst and DMF as... 
酯化反应 | 前列腺癌 | 合成 | 评价 | 催化活性 | IC50 | 衍生物 | 测定结果 | silver oxide | amino acid | 7 | anticancer activity | taxane | epi | C‐13 derivative of taxane | C-13 derivative of taxane | 7-epi-taxane | METABOLISM | TAXOL ANALOGS | AGENTS | CHEMISTRY, MULTIDISCIPLINARY | Care and treatment | Hydroxides | Analysis | Pharmacy | Drugstores | Amino acids | Medicine, Chinese | Drug discovery | Cancer | Rodents
Journal Article
Natural Product Research, ISSN 1478-6419, 06/2018, pp. 1 - 7
Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro... 
1-Deoxybaccatin VI | Cytotoxicity | Oxidation | Synthesis | Taxane
Journal Article
Asia-Pacific Journal of Clinical Oncology, ISSN 1743-7555, 2019
Internationally, there has recently been growing interest in the use of neoadjuvant pertuzumab and trastuzumab in patients with non-metastatic HER-2 positive... 
neoadjuvant | pathological complete response | pertuzumab | HER2 | taxane
Journal Article
Oncotarget, ISSN 1949-2553, 02/2019, Volume 10, Issue 11, pp. 1209 - 1216
Adjuvant chemotherapy has an indisputable value for early breast cancer patients. Anthracycline and taxane-based regimens (TaxAC) have not been proven superior... 
Journal Article
Gan to kagaku ryoho. Cancer & chemotherapy, ISSN 0385-0684, 11/2014, Volume 41, Issue 12, pp. 1951 - 1953
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2019, Volume 310, pp. 47 - 57
Ephrin A2 targeted immunoliposomes incorporating pH-sensitive taxane prodrugs were developed for sustained delivery of active drug to solid tumors. Here we... 
Liposome | Taxane | Prodrug | Drug loading | Tumor targeting | Ephrin A2 | Index Medicus
Journal Article
Chemical Science, ISSN 2041-6520, 05/2013, Volume 4, Issue 5, pp. 2122 - 2126
A new type of degradable, nanoscopic polymer assembly containing ultra-high levels of drug loading via covalent attachment within amphiphilic core-shell... 
CELLS | THERAPY | CT-2103 | TAXOL | TAXANE | FORMULATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | Nanoparticles | Drugs | Conjugates | Platforms | Solubility | Jewelry | Nanostructure | Conjugation
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 53, pp. 30053 - 30065
Ovarian cancer is the most aggressive female reproductive tract tumours. Taxane (paclitaxel; TX) is widely used for ovarian cancer treatment. However, ovarian... 
LATS2 | Taxane | MiR-363 | Chemoresistance | Ovarian cancer
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. AB39 - AB39
A taxane algorithm was developed based on retrospective clinical data for patients with hypersensitivity reactions to taxanes and initiated at Dana Farber... 
ALLERGY | IMMUNOLOGY | Algorithms | Desensitization | Taxanes | Hypersensitivity
Journal Article
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