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1. The story of taxol
: nature and politics in the pursuit of an anti-cancer drug
by Goodman, Jordan and Walsh, Vivien
2001, ISBN 9780521561235, xiii, 282
Treatment | Harvesting | Paclitaxel | Economic aspects | Research | Pacific yew | Political aspects | Cancer
Book
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2. Full Text Rethinking production of Taxol® (paclitaxel) using endophyte biotechnology
by Kusari, Souvik and Singh, Satpal and Jayabaskaran, Chelliah
Trends in Biotechnology, ISSN 0167-7799, 2014, Volume 32, Issue 6, pp. 304 - 311
Highlights • Fungal endophytes have been shown to produce Taxol® (paclitaxel). • Industrial-scale Taxol® production using fungal endophytes has not yet been... 
Internal Medicine | Taxol® biosynthetic pathway | co-cultivation | red biotechnology | secondary metabolites | Taxol | endophytic fungi | endophyte biotechnology | biosynthetic pathway | bio-reactor design | plant–microbe interaction | genetic engineering | industrial bioprocess | MOLECULAR-GENETICS | TAXANE PRODUCTION | TAXUS-X-MEDIA | FUNGUS | ESCHERICHIA-COLI | bioreactor | GIBBERELLIN BIOSYNTHESIS | HOST-PLANT | TAXADIENE | Taxol (R) biosynthetic pathway | EVOLUTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | design | plant-microbe interaction | Taxol (R) | CHINENSIS VAR. MAIREI | Biotechnology - methods | Technology, Pharmaceutical - methods | Industrial Microbiology - methods | Paclitaxel - biosynthesis | Fungi - metabolism | Endophytes - metabolism | Biosynthetic pathway | Plant-microbe interaction | Secondary metabolites | Endophyte biotechnology | Bio-reactor design | Endophytic fungi | Genetic engineering | Co-cultivation | Industrial bioprocess | Red biotechnology | Studies | Fungi | Biotechnology | Metabolites | Taxonomy | Ecosystems | Biosynthesis
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3. Full Text The battle of “nano” paclitaxel
by Sofias, Alexandros Marios and Dunne, Michael and Storm, Gert and Allen, Christine
Advanced Drug Delivery Reviews, ISSN 0169-409X, 12/2017, Volume 122, pp. 20 - 30
Paclitaxel (PTX) is one of the three most widely used chemotherapeutic agents, together with doxorubicin and cisplatin, and is first or second line treatment... 
Oncology | Taxol | Nanomedicine | Abraxane | Nanotechnology | Paclitaxel
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4. Review - Taxol synthesis
by Guo, B. H and Kai, G. Y and Jin, H. B and Tang, K. X
Review - Taxol synthesis, 12/2006
Being a complex diterpenoid, the potent anticancer drug, Taxol, requires complicated steps for its biosynthesis. In the present article, recent advances on... 
biosynthesis pathway, cell culture, endophytic fungi, Taxol, Taxus
Journal
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5. Full Text Choosing the best chemotherapy agent to boost immune checkpoint inhibition activity
by Garassino, Marina Chiara and Torri, Valter and Colombo, Mario Paolo and Sica, Antonio
Cancer Research, ISSN 0008-5472, 10/2018, Volume 78, Issue 20, pp. 5729 - 5730
Despite the fact that reactivation of specific antitumor immunity through inhibition of immune checkpoints represents a formidable therapeutic weapon against... 
LIPOPOLYSACCHARIDE | KAPPA-B | ONCOLOGY | POLARIZATION | TAXOL
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6. Full Text The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)–tocopheryl polyethylene glycol succinate nanoparticles
by Zhang, Zhiping and Feng, Si-Shen
Biomaterials, ISSN 0142-9612, 2006, Volume 27, Issue 21, pp. 4025 - 4033
Paclitaxel is one of the most effective antineoplastic drugs. Its current clinical administration is formulated in Cremophor EL, which causes serious side... 
Cancer nanotechnology | Chemotherapy | Taxol | Biodegradable polymers | Cancer | CONTROLLED DELIVERY | MATERIALS SCIENCE, BIOMATERIALS | VITAMIN-E-TPGS | PERMEABILITY | ENGINEERING, BIOMEDICAL | biodegradable polymers | TAXOL(R) | FORMULATION | chemotherapy | cancer nanotechnology | cancer | Taxol (R) | ANTICANCER DRUGS | ABSORPTION | PLGA NANOPARTICLES | Succinates - chemistry | Humans | Delayed-Action Preparations - chemistry | Metabolic Clearance Rate | Polyethylene Glycols - chemistry | Paclitaxel - pharmacokinetics | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - toxicity | Delayed-Action Preparations - administration & dosage | Paclitaxel - chemistry | Paclitaxel - toxicity | Delayed-Action Preparations - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Diffusion | Paclitaxel - administration & dosage | Delayed-Action Preparations - toxicity | Caco-2 Cells | Cell Survival - drug effects | Nanostructures - ultrastructure | Capsules - chemistry | Antineoplastic Agents - chemistry | HT29 Cells | Particle Size | Capsules - toxicity | Nanostructures - chemistry | Biological products | Oncology, Experimental | Polymerization | Liquid chromatography | Research | Polyethylene glycol | Analysis | Nurses | Paclitaxel | Nuclear magnetic resonance | Nanotechnology
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7. Taxol
: science and applications
by Suffness, Matthew
1995, ISBN 9780849383823, 426
Paclitaxel
Book
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8. Full Text Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas
by Yu, Chunna and Luo, Xiujun and Zhan, Xiaori and Hao, Juan and Zhang, Lei and L Song, Yao-Bin and Shen, Chenjia and Dong, Ming
BMC Plant Biology, ISSN 1471-2229, 09/2018, Volume 18, Issue 1, pp. 197 - 12
Background: Plants of the genus Taxus have attracted much attention owing to the natural product taxol, a successful anti-cancer drug. T. fuana and T.... 
Metabolomics | Flavonoids | Taxus | Metabolite | Taxol | Germplasm resources | CELLS | BACCATIN III | X-MEDIA | TAXOL BIOSYNTHESIS | PACLITAXEL TAXOL | YEWS TAXUS | TAXANE DITERPENOIDS | PLANT SCIENCES | CHINENSIS VAR. MAIREI | ACCUMULATION | HETEROLOGOUS EXPRESSION | Metabonomic analysis | Genetic aspects | Yew | Endangered species | Metabolites | Comparative analysis | Seeds | Adaptiveness | Biosynthesis | Metabolism | Intermediates | Endangered & extinct species | Germplasm | Natural products | Paclitaxel | Cancer
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9. Full Text MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
by Zhou, Ming and Liu, Zixing and Zhao, Yuhua and Ding, Yan and Liu, Hao and Xi, Yaguang and Xiong, Wei and Li, Guiyuan and Lu, Jianrong and Fodstad, Oystein and Riker, Adam I and Tan, Ming
Journal of Biological Chemistry, ISSN 0021-9258, 07/2010, Volume 285, Issue 28, pp. 21496 - 21507
Paclitaxel (Taxol) is an effective chemotherapeutic agent for treatment of cancer patients. Despite impressive initial clinical responses, the majority of... 
LACTATE-DEHYDROGENASE | CAENORHABDITIS-ELEGANS | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | DEREGULATION | PROLIFERATION | MIR-125B | OVARIAN-CANCER | TAXOL-INDUCED APOPTOSIS | MICROTUBULE DYNAMICS | Paclitaxel - pharmacology | Oligonucleotide Array Sequence Analysis | Cell Survival | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | MicroRNAs - metabolism | Reverse Transcriptase Polymerase Chain Reaction | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Breast Neoplasms - genetics | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Apoptosis | Molecular Bases of Disease | Chemotherapy | MicroRNA | Taxol | Oncogene | Paclitaxel | miR-125b | Bak1 | Breast Cancer | Drug Resistance | Cell Biology
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10. Full Text Chemotherapeutic engineering: Vitamin E TPGS-emulsified nanoparticles of biodegradable polymers realized sustainable paclitaxel chemotherapy for 168 h in vivo
by Feng, Si-Shen and Zhao, Lingyun and Zhang, Zhiping and Bhakta, Gajadhar and Yin Win, Khin and Dong, Yuancai and Chien, Shu
Chemical Engineering Science, ISSN 0009-2509, 2007, Volume 62, Issue 23, pp. 6641 - 6648
A full spectrum of proof-of-concept research from nanoparticle preparation and characterization, drug release, cellular uptake and cytotoxicity, to... 
Pharmaceutical nanotechnology | Anticancer drugs | Cancer nanotechnology | Drug delivery | formula omitted | Nanomedicine | Controlled release | Nanobiotechnology | Taxol | VITRO | CONTROLLED-RELEASE | nanomedicine | TAXOL(R) | nanobiotechnology | drug delivery | FORMULATION | anticancer drugs | CANCER | CELLULAR UPTAKE | DELIVERY | ANTITUMOR AGENTS | ENGINEERING, CHEMICAL | pharmaceutical nanotechnology | controlled release | cancer nanotechnology | NANOSPHERES | Taxol (R)
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11. Full Text Refined structure of αβ-tubulin at 3.5 Å resolution
by Löwe, J and Li, H and Downing, K.H and Nogales, E
Journal of Molecular Biology, ISSN 0022-2836, 11/2001, Volume 313, Issue 5, pp. 1045 - 1057
tubulin | taxol | zinc-sheets | crystallographic refinement | electron crystallography | Electron crystallography | Crystallographic refinement | Tubulin | Zinc-sheets | Taxol
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12. Full Text Multiwell stiffness assay for the study of cell responsiveness to cytotoxic drugs
by Zustiak, Silviya and Nossal, Ralph and Sackett, Dan L
Biotechnology and Bioengineering, ISSN 0006-3592, 02/2014, Volume 111, Issue 2, pp. 396 - 403
A novel multiwell stiffness assay based on collagen‐coated polyacrylamide gel was developed. The stiffness assay, due to its multiwell plate format, could be... 
paclitaxel (Taxol®) | cancer | drug resistance | substrate stiffness | polyacrylamide | Substrate stiffness | Paclitaxel (Taxol®) | Drug resistance | Polyacrylamide | Cancer | CHEMOSENSITIVITY | HYDROGELS | TISSUE | PROLIFERATION | paclitaxel (Taxol (R)) | ATOMIC-FORCE MICROSCOPY | MATRIX STIFFNESS | EPITHELIAL-CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SUBSTRATE | CREASING INSTABILITY | MORPHOLOGY | Cells - drug effects | Hydrogel, Polyethylene Glycol Dimethacrylate | Humans | Chemical Phenomena | Cell Line, Tumor | Inhibitory Concentration 50 | Acrylic Resins | Antineoplastic Agents - pharmacology | Extracellular Matrix - chemistry | Antimitotic agents | Atomic force microscopy | Antineoplastic agents | Collagen
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13. Full Text Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431
by Yang, Yanfang and Zhao, Hainan and Barrero, Roberto A and Zhang, Baohong and Sun, Guiling and Wilson, Iain W and Xie, Fuliang and Walker, Kevin D and Parks, Joshua W and Bruce, Robert and Guo, Guangwu and Chen, Li and Zhang, Yong and Huang, Xin and Tang, Qi and Liu, Hongwei and Bellgard, Matthew I and Qiu, Deyou and Lai, Jinsheng and Hoffman, Angela
BMC Genomics, ISSN 1471-2164, 01/2014, Volume 15, Issue 1, pp. 69 - 69
Background: Paclitaxel (Taxol (TM)) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted... 
Endophytic fungi | Genome sequence | Taxol | Penicillium aurantiogriseum NRRL 62431 | Paclitaxel | Horizontal gene transfer | NATURAL-PRODUCT | TAXUS-BREVIFOLIA | TAXOL BIOSYNTHESIS | Taxol (TM) | TAXANES | OVERPRODUCTION | EVOLUTION | ANTICANCER | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PACIFIC YEW | GENETICS & HEREDITY | DIVERSITY | Molecular Sequence Data | Mixed Function Oxygenases - metabolism | Chromatography, High Pressure Liquid | Phylogeny | Acyltransferases - metabolism | Acyltransferases - genetics | Fungi - genetics | Farnesyltranstransferase - classification | Farnesyltranstransferase - metabolism | Genome, Fungal | Base Sequence | Mass Spectrometry | Acyltransferases - classification | Paclitaxel - analysis | Paclitaxel - biosynthesis | Gene Transfer, Horizontal | Fungal Proteins - genetics | Fungal Proteins - classification | Penicillium - genetics | Mixed Function Oxygenases - classification | Sequence Analysis, RNA | Farnesyltranstransferase - genetics | Penicillium - classification | Mixed Function Oxygenases - genetics | Fungal Proteins - metabolism | Fungi | Proteins | Studies | Trees | Genomics | Genes | Phylogenetics | Biosynthesis | Genomes | Maximum likelihood method | Bioinformatics | Data bases
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14. Full Text Methoxy poly(ethylene glycol) conjugated denatured bovine serum albumin micelles for effective delivery of camptothecin
by Zhang, Liming and Lu, Zhuoxuan and Li, Xiaolong and Deng, Yan and Zhang, Fengqin and Ma, Chao and He, Nongyue
Polymer Chemistry, ISSN 1759-9954, 08/2012, Volume 3, Issue 8, pp. 1958 - 1961
A novel nontoxic denatured bovine serum albumin (dBSA)-based platform for effectively delivering drugs was prepared. It was demonstrated that the as-prepared... 
NANOPARTICLES | DESIGN | POLYMER SCIENCE | BOUND PACLITAXEL | TAXOL | DRUGS | DOXORUBICIN | POLYMERIC MICELLES | BINDING | CARRIERS
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15. Full Text Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: Synthesis, formulation, characterization and in vitro drug release
by Zhang, Zhiping and Feng, Si-Shen
Biomaterials, ISSN 0142-9612, 2006, Volume 27, Issue 2, pp. 262 - 270
Paclitaxel is one of the best anticancer drugs, which has excellent therapeutic effects against a wide spectrum of cancers. The formulation of paclitaxel used... 
Cancer nanotechnology | Chemotherapy | Taxol | Biodegradable polymers | Paclitaxel | paclitaxel | MATERIALS SCIENCE, BIOMATERIALS | VITAMIN-E-TPGS | PACLITAXEL TAXOL(R) | ENGINEERING, BIOMEDICAL | biodegradable polymers | chemotherapy | SOLVENT | EMULSIFIERS | DELIVERY | cancer nanotechnology | SUCCINATE | POLYMERIC NANOSPHERES | Taxol (R) | ANTICANCER DRUGS | CREMOPHOR EL | Paclitaxel - metabolism | Molecular Weight | Humans | Vitamin E - analogs & derivatives | Polyethylene Glycols - chemistry | Nanostructures | Drug Carriers - chemistry | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Surface Properties | Polyesters | Antineoplastic Agents, Phytogenic - metabolism | Molecular Structure | Vitamin E - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Polyethylene Glycols - metabolism | Lactic Acid - chemistry | Lactic Acid - metabolism | Antineoplastic Agents, Phytogenic - chemistry | Paclitaxel - therapeutic use | Neoplasms - drug therapy | Particle Size | Drug Therapy - methods | Vitamin E - metabolism | Polymers - chemistry | Polymers - metabolism | Nanoparticles | Biological products | Vitamin E | Polymerization | Liquid chromatography | Glycols | Chemical properties | Ethers | Nanotechnology | Cancer
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16. Full Text The chemistry and pharmacology of taxol and its derivatives
by Farina, Vittorio
1995, Pharmacochemistry library, ISBN 0444817719, Volume 22, 350
Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and... 
Paclitaxel | Derivatives | Other branches of medicine
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17. Full Text Highway to cell
by Häfner, Sophia
Microbes and Infection, ISSN 1286-4579, 02/2017, Volume 19, Issue 2, pp. 79 - 83
INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | CYTOSKELETON | TAXOL
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18. Full Text Taxol produced from endophytic fungi induces apoptosis in human breast, cervical and ovarian cancer cells
by Wang, Xin and Wang, Chao and Sun, Yu-Ting and Sun, Chuan-Zhen and Zhang, Yue and Wang, Xiao-Hua and Zhao, Kai
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2015, Volume 16, Issue 1, pp. 125 - 131
HeLa | Fungal taxol | MCF-7 | HO8910 | Apoptosis
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