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American Journal of Translational Research, ISSN 1943-8141, 2017, Volume 9, Issue 2, pp. 442 - 453
The T-box gene family refers to a group of transcription factors that share a highly conserved, sequencespecific DNA-binding domain (T-box) containing around... 
SNP rs3825214 | T-box gene TBX5 mutation | Atrial fibrillation | Holt-Oram syndrome | Meta-analysis | MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | STEM-CELLS | meta-analysis | ATRIAL-FIBRILLATION | LIMB | atrial fibrillation | GENE | ONCOLOGY | box gene TBX5 mutation | CONGENITAL HEART-DISEASE | TBX5 MUTATION | HOLT-ORAM-SYNDROME | SMALL PATELLA SYNDROME | EXPRESSION
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 08/2012, Volume 20, Issue 8, pp. 863 - 869
Holt-Oram syndrome (HOS) is a rare autosomal dominant heart-hand syndrome due to mutations in the TBX5 transcription factor. Affected individuals can have... 
congenital heart disease | limb anomalies | TBX5 | array-CGH | duplication | Holt-Oram syndrome | PARTIAL TRISOMY 12Q | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATRIAL-FIBRILLATION | LIMB | HEART-DISEASE | GENE | GENETICS & HEREDITY | FUNCTIONAL-ANALYSIS | MUTATIONS | CARDIOGENESIS | TRANSCRIPTION FACTOR | MANIFESTATIONS | Gene Duplication | Computational Biology - methods | Humans | Lower Extremity Deformities, Congenital - diagnosis | Male | Upper Extremity Deformities, Congenital - genetics | Heart Septal Defects, Atrial - diagnosis | T-Box Domain Proteins - genetics | DNA Copy Number Variations | Upper Extremity Deformities, Congenital - diagnosis | Young Adult | Heart Defects, Congenital - genetics | Phenotype | Comparative Genomic Hybridization | Abnormalities, Multiple - diagnosis | Adult | Family | Female | Heart Defects, Congenital - diagnosis | Heart Septal Defects, Atrial - genetics | Chromosomes, Human, Pair 12 | Lower Extremity Deformities, Congenital - genetics | Abnormalities, Multiple - genetics | TBX5 gene | Heart | Conduction | Transcription factors | Exons | Genomics | Genes | Tbx5 protein | Stenosis | Dislocation | Defects | Cell adhesion & migration | Fibrillation | Genetics | Rheumatic heart disease | Localization | Heart diseases | Hypoplasia | Breakpoints | Phenotypes | Mitral valve | Congenital diseases | Splicing | Introns | Lung diseases | Coronary heart disease | Haploinsufficiency | Alleles | Mutation | Limbs | Head | Finger | tbx5 protein | Sinus | genomics | Holt–Oram syndrome
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 10
Reprogramming of fibroblasts to induced cardiomyocyte-like cells (iCMs) offers potential strategies for new cardiomyocyte generation. However, a major... 
EFFICIENCY | MULTIDISCIPLINARY SCIENCES | FIBROBLASTS | Proteins | Splicing | Contractility | Tbx5 protein | Fibroblasts | Cardiomyocytes | MEF2C protein | Structure-function relationships | Expression vectors
Journal Article
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2018, Volume 22, Issue 22, pp. 7841 - 7848
Journal Article
Developmental Cell, ISSN 1534-5807, 11/2016, Volume 39, Issue 4, pp. 480 - 490
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 03/2018, Volume 145, Issue 6, pp. dev159830 - dev159830
In tetrapods, , and Hox cluster genes are crucial for forelimb and hindlimb development and mutations in these genes are responsible for congenital limb... 
Hoxc10 | Hoxa13 | Hoxd13 | ChIPseq | Pitx1 | Tbx5 | Limb specification | Tbx4 | Regulatory network | Transcription factors | Genomes | Mutation | Buds | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Journal Article