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2005, ISBN 0691130426, xiii, 374
Biology and politics have converged today across much of the industrialized world. Debates about genetically modified organisms, cloning, stem cells, animal... 
Democracy and science | Großbritannien | USA | Deutschland | Forschungsgegenstand | Bioethik | Demokratie | Biotechnologie | Europa | Forschungspolitik | Biotechnology | International Relations | TCB | Public Policy | JPQB | Science | General | Political Science | PDR | Biological Sciences | United States | Europe | SCIENCE | POLITICAL SCIENCE
Book
Journal of molecular structure, ISSN 0022-2860, 04/2013, Volume 1038, Issue C, pp. 12 - 18
► [EMIM]+ cation adopts a non-planer conformation in the most stable form. ► Weaker inter-ionic interactions in [EMIM]+[TCB]− compared to [EMIM]+[TCB]−. ►... 
Ionic liquids | Infrared spectroscopy | NBO | Raman spectroscopy | [Emim]+[TCB] | Density Functional Theory | TCB | Emim | MOLECULAR-INTERACTIONS | ANIONS | [Emim](+)[TCB](-) | LIQUID | CHEMISTRY, PHYSICAL | SALTS | CATIONS | ENERGY DECOMPOSITION ANALYSIS | BOND | WATER | Invisibility | Analysis | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 563, Issue 7730, pp. 209 - 213
Tc toxins secrete toxic enzymes into host cells using a unique syringe-like injection mechanism. They are composed of three subunits, TcA, TcB and TcC. TcA... 
TRANSLOCATION | TERMINUS | MODELS | ALIGNMENT | MULTIDISCIPLINARY SCIENCES | INSECTICIDAL TOXINS | RESOLUTION | PROTEASOME | VALIDATION | PHOTORHABDUS | Tc toxins secrete toxic enzymes into host cells using a unique syringe-like injection mechanism. They are composed of three subunits, TcA, TcB and TcC. TcA forms the translocation channel and the TcB-TcC heterodimer functions as a cocoon that shields the toxic enzyme. Binding of the cocoon to the channel triggers opening of the cocoon and translocation of the toxic enzyme into the channel. Here we show in atomic detail how the assembly of the three components activates the toxin. We find that part of the cocoon completely unfolds and refolds into an alternative conformation upon binding. The presence of the toxic enzyme inside the cocoon is essential for its subnanomolar binding affinity for the TcA subunit. The enzyme passes through a narrow negatively charged constriction site inside the cocoon, probably acting as an extruder that releases the unfolded protein with its C terminus first into the translocation channel | INJECTION MECHANISM | Protein Unfolding | Protein Refolding | Models, Molecular | ADP Ribose Transferases - ultrastructure | Bacterial Toxins - chemistry | Protein Transport | Cryoelectron Microscopy | Photorhabdus - chemistry | Bacterial Toxins - biosynthesis | Multiprotein Complexes - metabolism | Multiprotein Complexes - ultrastructure | Bacterial Toxins - metabolism | Multiprotein Complexes - chemistry | Cytotoxins - biosynthesis | Multiprotein Complexes - biosynthesis | Models, Biological | Cytotoxins - chemistry | Cytotoxins - metabolism | Protein Conformation | Photorhabdus - ultrastructure | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - metabolism | Proteins | Binding | Translocation | Enzymes | Microscopy | Protein folding | Toxins | Software | Symmetry
Journal Article
Gastrointestinal Endoscopy, ISSN 0016-5107, 2011, Volume 74, Issue 5, pp. 1010 - 1018
Journal Article
The Journal of infectious diseases, ISSN 0022-1899, 11/2018, Volume 218, Issue 5, pp. S658 - S661
Antibody therapy has been used to treat a variety of diseases and the success of ZMapp and other monoclonal antibody-based therapies during the 2014-2016 West... 
Ebola virus | protection | transchromosomal bovines (TcB) | polyclonal antibodies | NONHUMAN-PRIMATES | INFECTIOUS DISEASES | VIRUS DISEASE | MICROBIOLOGY | INFECTION | IMMUNOLOGY | Supplement
Journal Article
Mechanism and machine theory, ISSN 0094-114X, 2018, Volume 121, pp. 731 - 744
•Generation of parametric first-order continuous rigid-body motion that is invariant with respect to chosen reference systems.•Generalization of Shoemake’s... 
de Casteljau | Screw motion | TCB spline | Bézier
Journal Article
Journal Article
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), ISSN 0302-9743, 2018, Volume 11063, pp. 253 - 262
Conference Proceeding
Protein Engineering, Design and Selection, ISSN 1741-0126, 07/2018, Volume 31, Issue 7-8, pp. 289 - 299
Abstract Technologies for the production of bispecific antibodies need to overcome two major challenges. The first one is correct heavy chain assembly, which... 
DESIGN | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | CrossMab | Angiopoietin-2 | EMICIZUMAB | IGG ANTIBODIES | VEGF-A | ANTITUMOR | CEA TCB | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | bispecific antibody | CELL BISPECIFIC ANTIBODY | GENERATION | EXPRESSION | Original
Journal Article
Journal of obstetric, gynecologic, and neonatal nursing, ISSN 0884-2175, 06/2012, Volume 41, Issue s1, pp. S44 - S44
Journal Article
Journal of power sources, ISSN 0378-7753, 2014, Volume 250, pp. 1 - 14
A typical large capacity sodium sulfur (NaS) battery is operated at 300–350 °C with 20–50 °C thermal fluctuations during its charging and discharging. In... 
Thermal compression bonding (TCB) | Thermomechanical failure | Finite element analysis (FEA) | Sodium sulfur (NaS) battery | ELECTROCHEMISTRY | ROOM-TEMPERATURE | ENERGY & FUELS | ENERGY-STORAGE | BATTERIES | Finite element method | Sulfur compounds | Sulfur | Analysis
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2020, Volume 80, Issue 13, pp. 2903 - 2913
CD8-expressing T cells are the main effector cells in cancer immunotherapy. Treatment-induced changes in intratumoral CD8(+) T cells may represent a biomarker... 
CEA TCB | PREDICTIVE BIOMARKER | MODELS | ONCOLOGY | URELUMAB | BLOCKADE | EXPRESSION | LYMPHOCYTES
Journal Article
ACM Transactions on Internet Technology (TOIT), ISSN 1533-5399, 09/2017, Volume 17, Issue 4, pp. 1 - 21
Provenance is an increasingly important tool for understanding and even actively preventing system intrusion, but the excessive storage burden imposed by... 
Provenance | TCB | integrity | mandatory policy | Mandatory policy | Integrity | COMPUTER SCIENCE, SOFTWARE ENGINEERING | COMPUTER SCIENCE, INFORMATION SYSTEMS
Journal Article
Journal of molecular liquids, ISSN 0167-7322, 12/2016, Volume 224, pp. 1124 - 1130
Journal Article