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axin (7) 7
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OncoTargets and Therapy, ISSN 1178-6930, 10/2019, Volume 12, pp. 8055 - 8062
Yanbin Sun,1 Jingjing Xu2 1Department of Thoracic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province 110001,... 
lung cancer | TCF-4 | lncRNA | XIST
Journal Article
DIABETOLOGIA, ISSN 0012-186X, 01/2007, Volume 50, Issue 1, pp. 5 - 7
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 11/2001, Volume 159, Issue 5, pp. 1613 - 1617
At the invasion front of well-differentiated colorectal adenocarcinomas, the oncogene beta -catenin is found in the nuclear compartment of tumor cells. Under... 
TARGET | TCF-4 | PATHWAY | MYC | CELL-PROLIFERATION | PATHOLOGY | EXPRESSION | CANCER | D1
Journal Article
Liver international : official journal of the International Association for the Study of the Liver, ISSN 1478-3223, 8/2013, Volume 33, Issue 7, pp. 1100 - 1112
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 04/2013, Volume 31, Issue 3, pp. 228 - 236
High‐mobility group A1 (HMGA1) encodes proteins that act as mediators in viral integration, modification of chromatin structure, neoplastic transformation and... 
high‐mobility group A1 (HMGA1) | TCF‐4 target gene | oncogene | Wnt/β‐catenin/TCF‐4 pathway | colon cancer | transcriptional activation | High-mobility group A1 (HMGA1) | Colon cancer | TCF-4 target gene | Transcriptional activation | Oncogene | Wnt/β-catenin/TCF-4 pathway | catenin | TCF-4 pathway | BIOCHEMISTRY & MOLECULAR BIOLOGY | HMG-I/Y | BETA-CATENIN | CELL BIOLOGY | HIGH-MOBILITY-GROUP-A1 GENE | GENE-EXPRESSION | CYCLOOXYGENASE-2 EXPRESSION | high-mobility group A1 (HMGA1) | FAMILIAL ADENOMATOUS POLYPOSIS | Wnt | TARGET GENE | C-JUN | PROTEINS | APC MUTATIONS | HMGA1b Protein - metabolism | Humans | Transcriptional Activation - drug effects | Wnt Proteins - metabolism | Transcription Factor 7-Like 2 Protein - metabolism | Colonic Neoplasms - metabolism | Adenomatous Polyposis Coli Protein - genetics | HMGA1b Protein - genetics | Promoter Regions, Genetic | HMGA1a Protein - genetics | Transcription Factor 7-Like 2 Protein - genetics | Signal Transduction | HCT116 Cells | Mice, Inbred C57BL | Mice, Transgenic | Down-Regulation - drug effects | HMGA1a Protein - metabolism | beta Catenin - metabolism | beta Catenin - genetics | HT29 Cells | Up-Regulation - drug effects | Animals | 5' Untranslated Regions | Colonic Neoplasms - pathology | Adenomatous Polyposis Coli Protein - metabolism | Protein Binding | Mice | Zinc - pharmacology
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2006, Volume 38, Issue 3, pp. 320 - 323
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2019, Volume 508, Issue 3, pp. 675 - 681
Activation of T cell factor-4 (TCF-4) is causally linked to the development of lung carcinoma, while the mechanism of sequence-dependent TCF-4 activity is... 
TCF-4 | Wnt signaling | Lung carcinoma | Exon | Transcription | APOPTOSIS | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | CATENIN | CANCER | BIOPHYSICS | GENE | PATHWAY | EXPRESSION
Journal Article
Journal Article
Journal Article
Cell biochemistry and function, ISSN 0263-6484, 4/2013, Volume 31, Issue 3, pp. 228 - 236
High Mobility Group A1 (HMGA1) encodes proteins that act as mediators in viral integration, modification of chromatin structure, neoplastic transformation, and... 
β-catenin | colon cancer | High Mobility Group A1 (HMGA1) | TCF-4 target gene | Wnt | oncogene | TCF-4 Pathway | transcriptional activation
Journal Article
PROSTATE, ISSN 0270-4137, 08/2014, Volume 74, Issue 11, pp. 1118 - 1131
INTRODUCTION Physiologic testosterone continuously stimulates prostate stromal cell secretion of paracrine growth factors (PGFs), which if unopposed would... 
TCF-4 | c-MYC | catenin | SQUAMOUS TRANSDIFFERENTIATION | E-CADHERIN | BETA-CATENIN | CASTRATION | CANCER | VENTRAL PROSTATE | androgen receptor | human prostate epithelial cells | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | STEM-CELL | GROWTH-FACTOR | DIFFERENTIATION | Testosterone | Genetic transcription
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 10/2018, Volume 19, Issue 10
The Wnt/-catenin signaling pathway regulates cell proliferation and differentiation and its aberrant activation in cervical cancer has been described.... 
HPV-18 E6 | TCF-4 transcription factor | ACTIVATION | PROTEIN | HUMAN-PAPILLOMAVIRUS TYPE-16 | VARIANTS | catenin signaling | BIOCHEMISTRY & MOLECULAR BIOLOGY | CERVICAL-CANCER | BETA-CATENIN | CHEMISTRY, MULTIDISCIPLINARY | RISK HUMAN-PAPILLOMAVIRUS | HPV16 | HPV-18 E6I | COLORECTAL-CANCER | Wnt | EXPRESSION
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2013, Volume 144, Issue 2, pp. 381 - 391
Background & Aims The Wnt signaling pathway is required for maintenance of the intestinal epithelia; blocking this pathway reduces the proliferative capacity... 
Gastroenterology and Hepatology | Mouse model of colon cancer | Tnfrsf19 | β -Catenin | TCF | PATHWAYS | TCF-4 | TRANSCRIPTION | COLON | Mouse Model of Colon Cancer | EDAR | GENE | WNT/BETA-CATENIN | COLORECTAL-CANCER | beta-Catenin | SUPERFAMILY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Immunohistochemistry | Intestinal Mucosa - metabolism | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Wnt Signaling Pathway - physiology | Male | Receptors, Tumor Necrosis Factor - physiology | In Situ Hybridization | Neoplastic Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Neoplasms, Experimental | Neoplastic Stem Cells - pathology | Colorectal Neoplasms - metabolism | Receptors, G-Protein-Coupled - physiology | Mice, Inbred C57BL | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Animals | Cell Line, Tumor | RNA, Neoplasm - genetics | Mice | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Apoptosis | Intestinal Mucosa - pathology | Care and treatment | Chromatin | Molecular genetics | RNA | Low density lipoproteins | Fluorescence | Sulfates | T cells | Dextran | Colon cancer | Tumor necrosis factor | Stem cells | Universities and colleges | Cancer | Tumors
Journal Article
International Journal of Oncology, ISSN 1019-6439, 10/2011, Volume 39, Issue 4, pp. 883 - 890
Increasing evidence suggests that interplays between Wnt/beta-catenin and PI3K/AKT signaling cascades are involved in tumor development and progression.... 
Tcf-4 | AKT1 | Glioma | Transcription | ACTIVATION | transcription | BETA-CATENIN | CELL GROWTH | PI3K/AKT | GLIOBLASTOMA | THERAPY | ONCOLOGY | PATHWAY | COLORECTAL-CANCER | DOWNSTREAM | glioma | EXPRESSION
Journal Article
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 07/2015, Volume 46, Issue 4, pp. 554 - 559
Journal Article
Progress in Biochemistry and Biophysics, ISSN 1000-3282, 02/2009, Volume 36, Issue 2, pp. 175 - 181
Journal Article
Diabetes, ISSN 0012-1797, 03/2018, Volume 67, Issue 3, pp. 437 - 447
Polymorphism in TCF7L2, a component of the canonical Wnt signaling pathway, has a strong association with beta-cell dysfunction and type 2 diabetes through a... 
VARIANTS | GLUCOSE-METABOLISM | CLONING | TRANSCRIPTION-FACTOR-7-LIKE-2 TCF7L2 GENE | INSULIN-SECRETION | MOUSE | ENDOCRINOLOGY & METABOLISM | RISK | EXPRESSION | BETA-CATENIN/TCF-4 | DELETION | Glucose Intolerance - metabolism | Recombinant Proteins - therapeutic use | Bone Morphogenetic Protein 4 - genetics | Bacterial Proteins - chemistry | Male | Glucose Intolerance - pathology | Bone Morphogenetic Protein 4 - metabolism | Recombinant Fusion Proteins - metabolism | Transcription Factor 7-Like 2 Protein - metabolism | Glucose Intolerance - drug therapy | Transcription Factor 7-Like 2 Protein - chemistry | Insulin-Secreting Cells - metabolism | Pericytes - pathology | Luminescent Proteins - chemistry | Cell Differentiation | Insulin Secretion | Glucose Intolerance - physiopathology | Recombinant Proteins - metabolism | Bone Morphogenetic Protein 4 - therapeutic use | Transcription Factor 7-Like 2 Protein - genetics | Tissue Culture Techniques | Pericytes - metabolism | Bacterial Proteins - genetics | Gene Expression Regulation | Cell Communication | Cellular Microenvironment | Mice, Transgenic | Recombinant Fusion Proteins - chemistry | Insulin - metabolism | Animals | Glucose - metabolism | Bacterial Proteins - metabolism | Ligands | Luminescent Proteins - genetics | Insulin-Secreting Cells - pathology | Mutation | Luminescent Proteins - metabolism | Usage | Genetic aspects | Research | B cells | Diabetes | Diagnosis | Glucose tolerance tests | Genetic polymorphisms
Journal Article
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