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Meta Gene, ISSN 2214-5400, 09/2019, Volume 21, p. 100600
Type 2 diabetes mellitus is a metabolic condition associated with increased risk of multiple organ complications. Genetic variations in , , , and are shown to... 
UAE | T2DM | TCF7L2
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2018, Volume 50, Issue 11, pp. 1499 - 1500
Journal Article
Diabetes, ISSN 0012-1797, 07/2012, Volume 61, Issue 7, pp. 1726 - 1733
The majority of genetic risk variants for type 2 diabetes (T2D) affect insulin secretion, but the mechanisms through which they influence pancreatic islet... 
GRANULE DYNAMICS | GLUCOSE-HOMEOSTASIS | ISLETS | TCF7L2 GENE | KCNQ1 | ENDOCRINOLOGY & METABOLISM | SUSCEPTIBILITY LOCI | SECRETION | MELLITUS | ZINC TRANSPORTER ZNT8 | GENOME-WIDE ASSOCIATION | Receptors, Adrenergic, alpha-2 - genetics | Glucose Transporter Type 2 - genetics | KCNQ1 Potassium Channel - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Genetic Variation | Insulin-Secreting Cells - metabolism | Exocytosis - genetics | Glucose Transporter Type 2 - physiology | Transcription Factor 7-Like 2 Protein - physiology | Receptors, Adrenergic, alpha-2 - physiology | Insulin Secretion | Insulin-Secreting Cells - physiology | Genetic Predisposition to Disease - genetics | Transcription Factors - physiology | Transcription Factor 7-Like 2 Protein - genetics | Cells, Cultured | KCNQ1 Potassium Channel - physiology | Potassium Channels, Inwardly Rectifying - genetics | Transcription Factors - genetics | Homeodomain Proteins - genetics | Insulin-Secreting Cells - ultrastructure | Insulin - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Potassium Channels, Inwardly Rectifying - physiology | Homeodomain Proteins - physiology | Index Medicus | Abridged Index Medicus | Islet Studies | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Diabetologia, ISSN 0012-186X, 12/2007, Volume 50, Issue 12, pp. 2443 - 2450
Journal Article
Journal Article
Journal Article
FRONTIERS IN ENDOCRINOLOGY, ISSN 1664-2392, 02/2019, Volume 10, pp. 72 - 72
Introduction: Genetic polymorphisms in TCF7L2 are the strongest common risk variants for type 2 diabetes mellitus (T2D). We and others have shown that genetic... 
TCF7L2 | incretins | VARIANTS | WFS1 | SNP x SNP interactions | SENSITIVITY | HUMANS | RISK | gene x gene interactions | insulin secretion | hyperglycemic clamp | incretin resistance | ENDOCRINOLOGY & METABOLISM | ASSOCIATION | HORMONES | Type 2 diabetes | Genetic aspects | Single nucleotide polymorphisms
Journal Article