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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2019, Volume 63, Issue 1
Tedizolid phosphate, the prodrug of the active antibiotic tedizolid, is an oxazolidinone for the treatment of acute bacterial skin and skin structure... 
Linezolid | Pharmacodynamics | Pharmacokinetics | Oxazolidinones | Tedizolid | Neutropenia
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 01/2019, Volume 63, Issue 1
Tedizolid phosphate, the prodrug of the active antibiotic tedizolid, is an oxazolidinone for the treatment of acute bacterial skin and skin structure... 
SOFT-TISSUE INFECTIONS | ANTIMICROBIAL SUSCEPTIBILITY | pharmacodynamics | TR-701 | neutropenia | MICROBIOLOGY | PHASE-3 | linezolid | ACUTE BACTERIAL SKIN | OXAZOLIDINONE | SKIN-STRUCTURE INFECTIONS | pharmacokinetics | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | tedizolid | oxazolidinones
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 09/2017, Volume 39, Issue 9, pp. 1849 - 1857
Tedizolid phosphate is a next-generation oxazolidinone prodrug that is transformed into the active moiety tedizolid. Its indication is acute bacterial skin and... 
healthy Korean subjects | pharmacokinetics | oxazolidinone | tedizolid | bioavailability | MULTIDRUG-RESISTANT | RESISTANT STREPTOCOCCUS-PNEUMONIAE | ANTIMICROBIAL RESISTANCE | METHICILLIN-RESISTANT | ASIAN COUNTRIES | ACUTE BACTERIAL SKIN | SKIN-STRUCTURE INFECTIONS | SOUTH-KOREA | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | Prodrugs - administration & dosage | Organophosphates - adverse effects | Anti-Bacterial Agents - blood | Humans | Half-Life | Biological Availability | Male | Healthy Volunteers | Young Adult | Oxazoles - blood | Oxazoles - adverse effects | Adult | Anti-Bacterial Agents - adverse effects | Republic of Korea | Organophosphates - administration & dosage | Organophosphates - pharmacokinetics | Double-Blind Method | Administration, Oral | Organophosphates - blood | Oxazoles - pharmacokinetics | Cross-Over Studies | Prodrugs - adverse effects | Administration, Intravenous | Prodrugs - pharmacokinetics | Oxazoles - administration & dosage | Anti-Bacterial Agents - pharmacokinetics | Anti-Bacterial Agents - administration & dosage | Phosphates | Safety and security measures | Analysis | Pathogens | Bacterial infections | Oral administration | Dietary supplements | Staphylococcus infections | Pharmacology | FDA approval | Bioavailability | Metabolism | Switching | Proteins | Multidrug resistant organisms | Antibiotics | Metabolites | Protein synthesis | Linearity | Skin | Kinetics | Pharmacokinetics | Drug therapy | Drug dosages
Journal Article
Clinical Pharmacology in Drug Development, ISSN 2160-763X, 09/2018, Volume 7, Issue 7, pp. 788 - 794
Tedizolid phosphate is approved for the treatment of acute bacterial skin and skin structure infections in adults. We evaluated the pharmacokinetics of... 
oxazolidinone | antibacterial | ABSSSI | SSTI | tedizolid | population pharmacokinetics | SOFT-TISSUE INFECTIONS | SINGLE | PHASE-3 | RESISTANT STAPHYLOCOCCUS-AUREUS | TRIAL | ACUTE BACTERIAL SKIN | PRODRUG | SKIN-STRUCTURE INFECTIONS | PHARMACOLOGY & PHARMACY | AGE
Journal Article
Journal of Liposome Research, ISSN 0898-2104, 10/2018, Volume 28, Issue 4, pp. 322 - 330
Journal Article
Infectious Diseases and Therapy, ISSN 2193-8229, 03/2015, Volume 4, Issue 1, pp. 1 - 14
Treatment of multidrug-resistant Gram-positive infections continues to challenge clinicians as the emergence of new resistance mechanisms outpaces introduction... 
Enterococcus | Oxazolidinone | Gram-positive | Methicillin-resistant Staphylococcus aureus | Staphylococcus | Tedizolid | Vancomycin-resistant enterococci | Gram-positive bacteria | Staphylococcus infections | Antimicrobial agents | Review
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
Journal Article
Journal Article
Chinese Journal of New Drugs, ISSN 1003-3734, 03/2015, Volume 24, Issue 5, pp. 481 - 492
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 04/2013, Volume 7, pp. 243 - 265
Tedizolid phosphate (TR-701), a prodrug of tedizolid (TR-700), is a next-generation oxazolidinone that has shown favorable results in the treatment of acute... 
TR-701 FA | Linezolid resistance | Oxazolidinone | Skin and soft tissue infections | Tedizolid | TR-700 | SOFT-TISSUE INFECTIONS | UNITED-STATES | NOCARDIA-BRASILIENSIS | CHEMISTRY, MEDICINAL | skin and soft tissue infections | VANCOMYCIN RESISTANCE | TOREZOLID TR-700 | RESISTANT STAPHYLOCOCCUS-AUREUS | SPECTRUM ANALYSIS | CONFERS RESISTANCE | oxazolidinone | PHARMACOLOGY & PHARMACY | tedizolid | IN-VITRO ACTIVITY | linezolid resistance | Organophosphates - pharmacokinetics | Acute Disease | Organophosphates - adverse effects | Skin Diseases, Bacterial - microbiology | Gram-Positive Bacteria - drug effects | Humans | Oxazoles - pharmacokinetics | Drug Resistance, Bacterial | Biological Availability | Skin Diseases, Bacterial - drug therapy | Organophosphates - pharmacology | Tissue Distribution | Animals | Soft Tissue Infections - microbiology | Anti-Bacterial Agents - pharmacokinetics | Gram-Positive Bacteria - isolation & purification | Oxazoles - adverse effects | Anti-Bacterial Agents - adverse effects | Anti-Bacterial Agents - pharmacology | Oxazoles - pharmacology | Soft Tissue Infections - drug therapy | Research | Drug therapy | Antibacterial agents | Health aspects | Bacterial skin diseases | Heterocyclic aromatic compounds | Phosphates | Linezolid | Medical research | Dopamine | Hematology | Daptomycin | Clinical trials | Infections | Pharmacology | Vancomycin | Bioavailability | Tissues | Amine oxidase (flavin-containing) | Soft tissues | Microorganisms | Antibiotics | Bacteria | Myelosuppression | Skin | Strains (organisms) | Dopamine receptors
Journal Article