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Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2006, Volume 63, Issue 2, pp. 163 - 186
HIV-1 reverse transcriptase (RT) is one of the main targets for antiviral therapy. Two classes of RT inhibitors can be distinguished: those that are nucleoside... 
Biochemistry, general | HIV-1 | reverse transcriptase | AIDS | DNA synthesis | Biomedicine general | resistance | Cell Biology | drug | Life Sciences | chain termination | Life Sciences, general | NRTI | Drug | Resistance | Reverse transcriptase | Chain termination | ANTIRETROVIRAL-EXPERIENCED PATIENTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIGH-LEVEL RESISTANCE | IN-VITRO SELECTION | HUMAN-IMMUNODEFICIENCY-VIRUS | DEFICIENCY SYNDROME AIDS | CELL BIOLOGY | 3'-AZIDO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE-TERMINATED PRIMER | TYPE-1 REVERSE-TRANSCRIPTASE | POL GENE-MUTATIONS | TERMINATED DNA-SYNTHESIS | PRE-STEADY-STATE | Protein Structure, Tertiary | Nucleosides - chemistry | HIV-1 - drug effects | Humans | Reverse Transcriptase Inhibitors - pharmacology | HIV-1 - genetics | Reverse Transcriptase Inhibitors - chemistry | Nucleotides - chemistry | Drug Resistance, Viral - genetics | Virus Replication | Models, Biological | Nucleotides - pharmacology | Nucleosides - pharmacology | HIV Infections - drug therapy | HIV-1 - enzymology | Mutation | Antiretroviral drugs | Enzymes | Biosynthesis | Drug resistance | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Adaptations | Antiviral agents | RNA-directed DNA polymerase | Clinical trials | Nucleotides | Drug development | Nucleotide analogs | nucleosides | Reviews | nucleoside analogs | Primers | Development | Replication | Biochemistry, Molecular Biology
Journal Article
Journal Article
Journal Article
AIDS, ISSN 0269-9370, 07/2007, Volume 21, Issue 11, pp. 1405 - 1414
Journal Article
Journal Article