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Endocrine-related cancer, ISSN 1479-6821, 2013, Volume 20, Issue 4, pp. 603 - 610
Mutations 1 295 228 C>T and 1 295 250 C>T (termed C228T and C250T respectively), corresponding to −124 C>T and −146 C>T from the translation start site in the promoter of the telomerase reverse transcriptase... 
TERT promoter mutations | BRAF V600e mutation | Telomerase reverse transcriptase | Thyroid tumorigenesis | Thyroid cancers | SAP1A | MANAGEMENT | ONCOLOGY | thyroid cancers | BRAF MUTATION | TELOMERASE | thyroid tumorigenesis | ENDOCRINOLOGY & METABOLISM | telomerase reverse transcriptase | ASSOCIATION | BRAF V600E mutation | Promoter Regions, Genetic | Thyroid Neoplasms - genetics | Telomerase - genetics | Proto-Oncogene Proteins B-raf - genetics | Humans | Cell Line, Tumor | Mutation
Journal Article
Journal Article
by Remke, Marc and Ramaswamy, Vijay and Peacock, John and Shih, David J. H and Koelsche, Christian and Northcott, Paul A and Hill, Nadia and Cavalli, Florence M. G and Kool, Marcel and Wang, Xin and Mack, Stephen C and Barszczyk, Mark and Morrissy, A. Sorana and Wu, Xiaochong and Agnihotri, Sameer and Luu, Betty and Jones, David T. W and Garzia, Livia and Dubuc, Adrian M and Zhukova, Nataliya and Vanner, Robert and Kros, Johan M and French, Pim J and Van Meir, Erwin G and Vibhakar, Rajeev and Zitterbart, Karel and Chan, Jennifer A and Bognár, László and Klekner, Almos and Lach, Boleslaw and Jung, Shin and Saad, Ali G and Liau, Linda M and Albrecht, Steffen and Zollo, Massimo and Cooper, Michael K and Thompson, Reid C and Delattre, Oliver O and Bourdeaut, Franck and Doz, François F and Garami, Miklós and Hauser, Peter and Carlotti, Carlos G and Van Meter, Timothy E and Massimi, Luca and Fults, Daniel and Pomeroy, Scott L and Kumabe, Toshiro and Ra, Young Shin and Leonard, Jeffrey R and Elbabaa, Samer K and Mora, Jaume and Rubin, Joshua B and Cho, Yoon-Jae and McLendon, Roger E and Bigner, Darell D and Eberhart, Charles G and Fouladi, Maryam and Wechsler-Reya, Robert J and Faria, Claudia C and Croul, Sidney E and Huang, Annie and Bouffet, Eric and Hawkins, Cynthia E and Dirks, Peter B and Weiss, William A and Schüller, Ulrich and Pollack, Ian F and Rutkowski, Stefan and Meyronet, David and Jouvet, Anne and Fèvre-Montange, Michelle and Jabado, Nada and Perek-Polnik, Marta and Grajkowska, Wieslawa A and Kim, Seung-Ki and Rutka, James T and Malkin, David and Tabori, Uri and Pfister, Stefan M and Korshunov, Andrey and von Deimling, Andreas and Taylor, Michael D
Acta neuropathologica, ISSN 1432-0533, 2013, Volume 126, Issue 6, pp. 917 - 929
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 43, pp. 17426 - 17431
The telomerase reverse transcriptase (TERT) promoter, an important element of telomerase expression, has emerged as a target of cancer-specific mutations... 
Relapse | Urinary bladder neoplasms | Carcinoma | Urinary bladder | Alleles | Cell lines | Genetic mutation | Binding sites | Tumors | Cancer | Cancer genetics | Transcription factors | Noncoding mutations | TERT mutations | Reporter assays | noncoding mutations | WILD-TYPE P53 | CELLS | transcription factors | MULTIDISCIPLINARY SCIENCES | TUMOR | RISK | BREAST | reporter assays | cancer genetics | GENE-EXPRESSION | TRANSCRIPTIONAL REGULATION | EPIDEMIOLOGY | TELOMERE LENGTH | Luciferases - metabolism | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Promoter Regions, Genetic - genetics | Luciferases - genetics | Telomerase - genetics | Urinary Bladder Neoplasms - genetics | Base Sequence | DNA Mutational Analysis - statistics & numerical data | Urinary Bladder Neoplasms - pathology | Aged, 80 and over | Female | Carcinoma, Transitional Cell - genetics | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Carcinoma, Transitional Cell - pathology | Cell Line, Tumor | Biomarkers, Tumor - genetics | Polymorphism, Single Nucleotide | Mutation | Promoters (Genetics) | Gene mutations | Patient outcomes | Physiological aspects | Genetic aspects | Research | Bladder cancer | Genetic polymorphisms | Biological Sciences | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal Article