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science & technology (324) 324
life sciences & biomedicine (312) 312
animals (217) 217
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mice (133) 133
gene expression (121) 121
biochemistry & molecular biology (108) 108
doxycycline - pharmacology (82) 82
tet-on (82) 82
doxycycline (81) 81
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analysis (50) 50
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medicine, research & experimental (34) 34
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tet (33) 33
transgenes (33) 33
tet system (32) 32
genetic research (31) 31
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genes, reporter (28) 28
gene expression regulation (27) 27
genetics (27) 27
anti-bacterial agents - pharmacology (26) 26
apoptosis (26) 26
medical sciences (26) 26
neurosciences & neurology (26) 26
repressor proteins - genetics (26) 26
tetracyclines (26) 26
cancer (25) 25
deoxyribonucleic acid--dna (25) 25
physiological aspects (25) 25
plasmids (24) 24
rats (24) 24
stem cells (24) 24
tet-off (24) 24
tet-off system (24) 24
health aspects (22) 22
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biomedicine (21) 21
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molecular sequence data (21) 21
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base sequence (20) 20
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biochemical research methods (19) 19
developmental biology (19) 19
gene transfer techniques (19) 19
genetic therapy - methods (19) 19
lentivirus - genetics (19) 19
promoter regions, genetic - genetics (19) 19
cloning, molecular (18) 18
epigenetics (18) 18
hela cells (18) 18
methylation (18) 18
molecular biology (18) 18
rna (18) 18
bacterial proteins - genetics (17) 17
dna-binding proteins - genetics (17) 17
mutation (17) 17
plant sciences (17) 17
rodents (17) 17
disease models, animal (16) 16
enzymes (16) 16
gene expression regulation, neoplastic (16) 16
inducible (16) 16
medicine (16) 16
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1. Full Text Drug Inducible CRISPR/Cas Systems
by Zhang, Jingfang and Chen, Li and Zhang, Ju and Wang, Yu
Computational and structural biotechnology journal, ISSN 2001-0370, 2019, Volume 17, pp. 1171 - 1177
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology
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2. Tet-On systems for doxycycline-inducible gene expression
by Das, Atze T and Tenenbaum, Liliane and Berkhout, Ben
Current gene therapy, ISSN 1566-5232, 06/2016, Volume 16, Issue 3, pp. 156 - 167
TTA | Doxycycline | Tet-On system | RtTA | TetR | Tet-Off system | Gene expression | Transcription regulation | Promoter Regions, Genetic | Escherichia coli - drug effects | Humans | Tetracycline - pharmacology | Bacterial Proteins - genetics | HIV-1 - genetics | Operon - genetics | Gene Expression Regulation - drug effects | Carrier Proteins - genetics | Operon - drug effects | Transfection | Escherichia coli - genetics | AIDS Vaccines - genetics | Doxycycline - pharmacology | Genetic Therapy - methods | Vaccines, Attenuated - genetics
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3. Full Text Inducible Genetic Code Expansion in Eukaryotes
by Koehler, Christine and Estrada Girona, Gemma and Reinkemeier, Christopher D and Lemke, Edward A
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 11/2020, Volume 21, Issue 22, pp. 3216 - 3219
T-REx | Tet-On | unnatural amino acid | PylRS | amber suppression | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Amino acids | Control systems | Codon | Transfer RNA | Proteins | Genetic code | Eukaryotes | tRNA | Fluorescence | Stop codon | Index Medicus | Communications | Communication
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4. Full Text Tetracycline-inducible gene expression system in Leishmania mexicana
by Kraeva, Natalya and Ishemgulova, Aygul and Lukeš, Julius and Yurchenko, Vyacheslav
Molecular and biochemical parasitology, ISSN 0166-6851, 11/2014, Volume 198, Issue 1, pp. 11 - 13
Gene expression | Tet-inducible system | Leishmania mexicana | Biochemistry & Molecular Biology | Parasitology | Life Sciences & Biomedicine | Science & Technology | Gene Expression | Protozoan Proteins - metabolism | Leishmaniasis, Cutaneous - parasitology | Humans | Tetracycline - pharmacology | Leishmania mexicana - metabolism | Leishmania mexicana - drug effects | Protozoan Proteins - genetics | Leishmania mexicana - genetics | Genetic research | Index Medicus
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5. Full Text A vanillic acid inducible expression system for Trypanosoma brucei
by Sunter, Jack D
Molecular and biochemical parasitology, ISSN 0166-6851, 05/2016, Volume 207, Issue 1, pp. 45 - 48
Inducible expression | Vanillic acid | Trypanosoma brucei | Gene regulation | Biochemistry & Molecular Biology | Parasitology | Life Sciences & Biomedicine | Science & Technology | DNA-Binding Proteins - metabolism | Gene Expression Regulation - drug effects | Promoter Regions, Genetic | Tetracycline - pharmacology | Operator Regions, Genetic | Trypanosoma brucei brucei - genetics | Binding Sites | Gene Order | Trypanosoma brucei brucei - drug effects | Vanillic Acid - pharmacology | Genetic Vectors - genetics | Index Medicus | RNAP, RNA polymerase | Short Technical Report | VanR, vanillic acid repressor | VanO, vanillic acid operator | TetO, tet operator | TetR, tetracycline repressor
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6. Full Text First inducible transgene expression in porcine large animal models
by Klymiuk, Nikolai and Böcker, Wolfgang and Schönitzer, Veronika and Bahr, Andrea and Radic, Tamara and Fröhlich, Thomas and Wünsch, Annegret and Keßler, Barbara and Kurome, Mayuko and Schilling, Eleonore and Herbach, Nadja and Wanke, Rüdiger and Nagashima, Hiroshi and Mutschler, Wolf and Arnold, Georg J and Schwinzer, Reinhard and Schieker, Matthias and Wolf, Eckhard
The FASEB journal, ISSN 0892-6638, 03/2012, Volume 26, Issue 3, pp. 1086 - 1099
tet‐on system | RANKL | CTLA‐4Ig | CTLA-4Ig | Tet-on system | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryo Transfer - methods | RANK Ligand - metabolism | Male | Dose-Response Relationship, Drug | Oocytes - cytology | Kidney - metabolism | Transfection | Abatacept | Swine | Female | Models, Animal | Animals, Newborn | Enzyme-Linked Immunosorbent Assay | Immunoconjugates - metabolism | Oocytes - metabolism | Transgenes - genetics | Cells, Cultured | Kidney - cytology | Reverse Transcriptase Polymerase Chain Reaction | Animals, Genetically Modified - metabolism | Gene Expression Regulation - drug effects | RANK Ligand - genetics | Animals | Animals, Genetically Modified - genetics | Chickens | Immunoconjugates - genetics | Doxycycline - pharmacology | Primary Cell Culture | Index Medicus
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7. Full Text Development of inducible cd19-car t cells with a tet-on system for controlled activity and enhanced clinical safety
by Gu, Xingjian and He, Dongyang and Li, Caixin and Wang, Hua and Yang, Guanghua
International journal of molecular sciences, ISSN 1661-6596, 11/2018, Volume 19, Issue 11, p. 3455
Tet-On | CAR | Inducible vector | CD19 | Doxycycline | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Index Medicus | inducible vector | doxycycline
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8. Full Text Doxycycline impairs mitochondrial function and protects human glioma cells from hypoxia-induced cell death: Implications of using tet-inducible systems
by Luger, Anna-Luisa and Sauer, Benedikt and Lorenz, Nadja I and Engel, Anna L and Braun, Yannick and Voss, Martin and Harter, Patrick N and Steinbach, Joachim P and Ronellenfitsch, Michael W
International journal of molecular sciences, ISSN 1661-6596, 05/2018, Volume 19, Issue 5, p. 1504
Mitochondria | Tumor metabolism | Doxycycline | Glioblastoma | Hypoxia-induced cell death | Tet-inducible system | Inducible gene expression | Tetracycline | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Index Medicus
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9. Full Text Forming megakaryocytes from murine‐induced pluripotent stem cells by the inducible overexpression of supporting factors
by Cullmann, Katharina and Jahn, Magdalena and Spindler, Markus and Schenk, Franziska and Manukjan, Georgi and Mucci, Adele and Steinemann, Doris and Boller, Klaus and Schulze, Harald and Bender, Markus and Moritz, Thomas and Modlich, Ute
Research and practice in thrombosis and haemostasis, ISSN 2475-0379, 01/2021, Volume 5, Issue 1, pp. 111 - 124
megakaryocytes | retroviral vectors | Genetic modification | iPS cells | Tet‐inducible system | Tet-inducible system | Fibroblasts | Cell culture | Transcription factors | Blood platelets | Leukemia | Stem cells
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10. Full Text Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia
by Pletnikov, M.V and Ayhan, Y and Nikolskaia, O and Xu, Y and Ovanesov, M.V and Huang, H and Mori, S and Moran, T.H and Ross, C.A
Molecular psychiatry, ISSN 1359-4184, 02/2008, Volume 13, Issue 2, pp. 173 - 186
Neurodevelopment | Schizophrenia | Tet-off system | Animal model | DISC1 | Lateral ventricle | Psychology. Psychoanalysis. Psychiatry | Psychoses | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Animals, Newborn | Lateral Ventricles - pathology | Molecular Weight | Humans | Gene Expression Regulation, Developmental - genetics | Behavior, Animal - physiology | Male | Mice, Transgenic | Schizophrenia - pathology | Nerve Tissue Proteins - genetics | Behavioral Symptoms - genetics | Animals | Schizophrenia - genetics | Schizophrenia - physiopathology | Brain - pathology | Female | Mice | Mutation | Behavioral Symptoms - etiology | Disease Models, Animal | Development and progression | Genetic aspects | Research | Translocation (Genetics) | Neurogenetics
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11. Full Text Inducible IFN-γ Expression for MHC-I Upregulation in Devil Facial Tumor Cells
by Ong, Chrissie E B and Lyons, Alan Bruce and Woods, Gregory M and Flies, Andrew S
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, pp. 3117 - 3117
IFN-γ | inducible | transmissible tumor | PD-L1 | apoptosis | Tet-Off system | MHC-I | DFTD | Life Sciences & Biomedicine | Immunology | Science & Technology | Up-Regulation | Immunotherapy - methods | Transcriptional Activation - genetics | Marsupialia - genetics | Marsupialia - immunology | Facial Neoplasms - veterinary | Transcriptional Activation - drug effects | Histocompatibility Antigens Class I - immunology | Cell Line, Tumor - drug effects | Facial Neoplasms - genetics | Interferon-gamma - metabolism | Promoter Regions, Genetic - drug effects | Histocompatibility Antigens Class I - metabolism | Cancer Vaccines - immunology | Doxycycline - administration & dosage | Animals | Facial Neoplasms - immunology | Cell Line, Tumor - immunology | Interferon-gamma - immunology | Cloning, Molecular | Interferon-gamma - genetics | Face | Cell Line, Tumor - metabolism | Facial Neoplasms - pathology | Index Medicus
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12. Role of hypoxia-inducible-1α in hepatocellular carcinoma cells using a Tet-on inducible system to regulate its expression in vitro
by Xu, Zongquan and Liu, Enyu and Peng, Cheng and Li, Yunguang and He, Zhaobin and Zhao, Chuanzong and Niu, Jun
Oncology reports, ISSN 1021-335X, 02/2012, Volume 27, Issue 2, pp. 573 - 578
Hepatocellular carcinoma cells | Tet-on inducible system | Proliferation | Hypoxia-inducible-1α | Apoptosis | Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Cycle - genetics | Cyclin D1 - metabolism | Cell Proliferation | Liver Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Inhibitor of Apoptosis Proteins - genetics | Cyclin A - metabolism | Humans | Caspase 3 - metabolism | Apoptosis - genetics | Genes, bcl-2 | Enzyme Activation - drug effects | Hep G2 Cells | Gene Expression Regulation - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - metabolism | Cell Line, Tumor | Doxycycline - pharmacology | Cyclin E - metabolism | Carcinoma, Hepatocellular - metabolism
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13. Full Text On the use of the T‐REx™ tetracycline‐inducible gene expression system in vivo
by Dobrovolsky, Vasily N and Heflich, Robert H
Biotechnology and bioengineering, ISSN 0006-3592, 10/2007, Volume 98, Issue 3, pp. 719 - 723
tet‐operator | transgenic | green fluorescent protein reporter | tetracycline repressor | tissue‐specific | Transgenic | Tet-operator | Tetracycline repressor | Green fluorescent protein reporter | Tissue-specific | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Recombinant Proteins - metabolism | Animals | Gene Expression - drug effects | Protein Engineering - methods | Gene Expression - genetics | Mice, Transgenic - genetics | Mice | Promoter Regions, Genetic - drug effects | Promoter Regions, Genetic - genetics | Tetracycline - administration & dosage | Proteins | Biotechnology | Biochemistry | Gene expression | Genes | Index Medicus
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14. Full Text A tetracycline‐inducible and skeletal muscle‐specific Cre recombinase transgenic mouse
by Rao, Pengcheng and Monks, D. Ashley
Developmental neurobiology (Hoboken, N.J.), ISSN 1932-8451, 05/2009, Volume 69, Issue 6, pp. 401 - 406
transgenesis | skeletal muscle | Cre‐loxP | Tet‐On | neuromuscular systems | Cre-loxP | Transgen- esis | Tet-On | Neuromuscular systems | Skeletal muscle | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Animals, Newborn | Recombination, Genetic - physiology | Gene Expression - drug effects | Embryo, Mammalian | Humans | RNA, Untranslated | Tetracycline - pharmacology | Actins - metabolism | Gene Expression Regulation, Developmental - drug effects | Mice, Transgenic | Muscle, Skeletal - metabolism | Actins - genetics | Proteins - genetics | Animals | Proteins - metabolism | Galactosides - metabolism | Integrases - metabolism | Mice | Protein Synthesis Inhibitors - pharmacology | Integrases - genetics | Recombination, Genetic - drug effects | Index Medicus
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