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Journal of Cellular Biochemistry, ISSN 0730-2312, 04/2016, Volume 117, Issue 4, pp. 860 - 871
Regular consumption of moderate amounts of ethanol has important health benefits on atherosclerotic cardiovascular disease (ASCVD). Overindulgence can cause... 
CANONICAL TGF‐β SIGNALING | TGF‐β RECEPTORS | TGF‐β ENHANCER | NON‐LIPID RAFT MICRODOMAINS | TGF-β RECEPTORS | NON-LIPID RAFT MICRODOMAINS | CANONICAL TGF-β SIGNALING | TGF-β ENHANCER | TGF-beta ENHANCER | C-REACTIVE PROTEIN | DI-LEUCINE FAMILY | TGF-beta RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALCOHOL-CONSUMPTION | CONSTITUTIVE ENDOCYTOSIS | CELL BIOLOGY | SIGNAL-TRANSDUCTION | GROWTH-FACTOR-BETA | CANONICAL TGF-beta SIGNALING | LIPID RAFTS | MEDIATED ENDOCYTOSIS | DEPENDENT ENDOCYTOSIS | PLASMA-CONCENTRATION | Cytoplasmic Vesicles - drug effects | Cell Fractionation | Phosphorylation | Receptors, Transforming Growth Factor beta - genetics | Epithelial Cells - metabolism | Luciferases - metabolism | Membrane Microdomains - metabolism | Epithelial Cells - drug effects | Caveolae - drug effects | Cytoplasmic Vesicles - chemistry | Lung - cytology | Luciferases - genetics | Dose-Response Relationship, Drug | Protein Isoforms - metabolism | Smad2 Protein - genetics | Cytoplasmic Vesicles - metabolism | Lung - metabolism | Epithelial Cells - cytology | Mink | Genes, Reporter | Signal Transduction | Caveolae - metabolism | Gene Expression Regulation | Smad2 Protein - metabolism | Caveolin 1 - genetics | Membrane Microdomains - chemistry | Caveolae - chemistry | Caveolin 1 - metabolism | Ethanol - pharmacology | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Membrane Microdomains - drug effects | Lung - drug effects | Transforming Growth Factor beta - metabolism | Cell Line, Transformed | Protein Isoforms - genetics | Index Medicus
Journal Article
Chest, ISSN 0012-3692, 04/2018, Volume 153, Issue 4, pp. 851 - 862
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2012, Volume 445, Issue 3, pp. 403 - 411
N-linked 21ycosylation is a critical determinant of protein structure and function, regulating processes such as protein folding, stability and localization,... 
Type II transforming growth factor β receptor (TβRII) | N-linked glycosylation | Cell surface transport | Transforming growth factor β sensitivity (TGF-β sensitivity) | Transforming growth factor β signalling (TGF-β signalling) | transforming growth factor beta signalling (TGF-beta signalling) | OLIGOSACCHARIDES | MEMBRANE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | MECHANISMS | type II transforming growth factor beta receptor (T beta RII) | transforming growth factor beta sensitivity (TGF-beta sensitivity) | CELL-SURFACE TRANSPORT | BIOSYNTHESIS | TUMOR-SUPPRESSOR | cell surface transport | PROTEINS | EXPRESSION | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - chemistry | Humans | Molecular Sequence Data | Glycosylation - drug effects | HEK293 Cells | Conserved Sequence | Cell Membrane - metabolism | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Alkaloids - pharmacology | Mutagenesis, Site-Directed | Protein-Serine-Threonine Kinases - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Hep G2 Cells | Sequence Homology, Amino Acid | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Protein-Serine-Threonine Kinases - chemistry | HeLa Cells | Transforming Growth Factor beta - metabolism | Amino Acid Substitution | Asparagine - chemistry | Index Medicus | transforming growth factor β sensitivity (TGF-β sensitivity) | KIF, kifunensine | dNG, deficient N-linked glycosylation | TβRII, type II TGF-β receptor | WT, wild-type | Tun, tunicamycin | FBS, fetal bovine serum | TGF-β, transforming growth factor β | Endo H, endoglycosidase H | HEK, human embryonic kidney | DAPI, 4′,6-diamidino-2-phenylindole | type II transforming growth factor β receptor (TβRII) | PNGase F, peptide N-glycosidase F | PEI, polyethyleneimine | GlcNAc, N-acetylglucosamine | transforming growth factor β signalling (TGF-β signalling) | TβRI, type I TGF-β receptor | ER, endoplasmic reticulum | PDI, protein disulfide-isomerase | RT, room temperature
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0168363 - e0168363
Transforming growth factor-beta (TGF-beta) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-beta signals... 
BREAST-CANCER | FIBROSIS | EPITHELIAL-CELL PROLIFERATION | GROWTH-FACTOR-BETA | MULTIDISCIPLINARY SCIENCES | NA+/K+-ATPASE | SMOOTH-MUSCLE-CELLS | PULMONARY MYOFIBROBLAST DIFFERENTIATION | FIBROBLASTS | CARDIAC-GLYCOSIDES | DIGITALIS | Phosphorylation | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Signal Transduction | Down-Regulation | Humans | Cells, Cultured | Lung - cytology | Sodium-Potassium-Exchanging ATPase - metabolism | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Fibroblasts - cytology | Lung - metabolism | Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Vimentin | Transcription factors | Smad protein | Mesenchyme | Laboratories | Epithelial cells | Transforming growth factor-b | Lung | Genes | Lung cancer | Ouabain | Transforming growth factor-a | Critical care | Smooth muscle | Lipids | Biology | Metastasis | Kinases | Cancer therapies | Fibronectin | Receptors | Cell growth | Actin | Rodents | Smad2 protein | Fibroblasts | Inhibition | Alveoli | Growth factors | Muscles | Breast cancer | Biophysics | Gene expression | Na+/K+-exchanging ATPase | Membrane proteins | Medicine | Signaling | Sodium | Potassium | Binding sites | Apoptosis | Index Medicus
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2012, Volume 16, Issue 9, pp. 2150 - 2160
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 06/2010, Volume 14, Issue 6a, pp. 1338 - 1346
This study investigated the effect of mechanical load on human mesenchymal stem cell (hMSC) differentiation under different exogenous transforming growth... 
TGF‐β | human bone marrow mesenchymal stem cells | mechanical load | chondrogenesis | TGF‐β pathway | fibrin‐polyurethane scaffold composites | Mechanical load | TGF-β1 | TGF-β pathway | Fibrin-polyurethane scaffold composites | Human bone marrow mesenchymal stem cells | Chondrogenesis | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | CYCLIC HYDROSTATIC-PRESSURE | ADULT | CELL BIOLOGY | TGF-beta | GROWTH-FACTOR-BETA | IN-VITRO CHONDROGENESIS | ARTICULAR-CARTILAGE | GENE-EXPRESSION | AGAROSE CULTURE | fibrin-polyurethane scaffold composites | TGF-beta pathway | DIFFERENTIATION | STROMAL CELLS | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Chondrogenesis - drug effects | Enzyme-Linked Immunosorbent Assay | Chondrogenesis - genetics | Glycosaminoglycans - metabolism | Humans | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Stress, Mechanical | Culture Media, Conditioned - pharmacology | DNA - metabolism | Gene Expression Regulation - drug effects | Tissue Scaffolds | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Transforming Growth Factor beta1 - pharmacology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 43, pp. 12192 - 12197
Intestinal stem cells (ISCs) are maintained by a niche mechanism, in which multiple ISCs undergo differential fates where a single ISC clone ultimately... 
Paneth cell | Intestinal stem cell | Tgfβ | TgfβR2 | Lgr5 | CONDITIONAL INACTIVATION | HOMEOSTASIS | TGF-BETA | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | COLON | lgr5 | Tgf beta R2 | intestinal stem cell | GENE | II RECEPTOR | PANETH CELLS | EXPRESSION | Tgf beta | PROGRESSION | Index Medicus | Biological Sciences
Journal Article
Journal Article