X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
tgf-β (7732) 7732
tgf-beta (5297) 5297
animals (5192) 5192
humans (5061) 5061
mice (2612) 2612
transforming growth factor beta - metabolism (2499) 2499
growth-factor-beta (2466) 2466
cell biology (2424) 2424
expression (2266) 2266
tgfβ (2228) 2228
signal transduction (2040) 2040
male (1970) 1970
biochemistry & molecular biology (1965) 1965
female (1936) 1936
oncology (1519) 1519
transforming growth factors (1264) 1264
fibrosis (1241) 1241
tgf beta (1216) 1216
cells, cultured (1207) 1207
cancer (1114) 1114
rats (1105) 1105
transforming growth factor beta - genetics (948) 948
tgf‐β (946) 946
apoptosis (941) 941
activation (922) 922
transforming growth factor beta - pharmacology (900) 900
gene expression (860) 860
cells (840) 840
immunology (835) 835
differentiation (813) 813
cell line, tumor (810) 810
gene-expression (796) 796
smad (784) 784
proteins (747) 747
bone morphogenetic proteins (743) 743
cell line (725) 725
metastasis (719) 719
immunohistochemistry (699) 699
inflammation (689) 689
transforming growth factor beta - physiology (687) 687
middle aged (678) 678
phosphorylation (677) 677
adult (671) 671
developmental biology (664) 664
epithelial-mesenchymal transition (645) 645
proliferation (635) 635
collagen (623) 623
receptors, transforming growth factor beta - metabolism (611) 611
growth factors (607) 607
receptor (607) 607
growth (604) 604
cell proliferation (601) 601
mice, inbred c57bl (586) 586
signal transduction - drug effects (558) 558
signal transduction - physiology (553) 553
cytokines (544) 544
disease models, animal (541) 541
pharmacology & pharmacy (539) 539
fibroblasts (528) 528
analysis (526) 526
gene (521) 521
inhibition (500) 500
medicine, research & experimental (492) 492
rna, messenger - metabolism (492) 492
in-vitro (488) 488
aged (487) 487
protein (480) 480
genetics & heredity (473) 473
transforming growth-factor-beta-1 (472) 472
research (469) 469
biophysics (468) 468
transforming growth factor-β (463) 463
extracellular matrix (457) 457
receptors, transforming growth factor beta - genetics (454) 454
emt (453) 453
transforming growth factor beta1 - metabolism (447) 447
reverse transcriptase polymerase chain reaction (444) 444
blotting, western (440) 440
cell differentiation (428) 428
angiogenesis (424) 424
in-vivo (423) 423
extracellular-matrix (414) 414
stem cells (413) 413
rats, sprague-dawley (407) 407
biology (403) 403
breast cancer (403) 403
mice, knockout (402) 402
induction (396) 396
mechanisms (390) 390
smad3 protein - metabolism (388) 388
up-regulation (385) 385
fibroblasts - metabolism (383) 383
endocrinology & metabolism (382) 382
rna, messenger - genetics (381) 381
gene expression regulation (379) 379
bmp (374) 374
down-regulation (372) 372
molecular sequence data (371) 371
smad proteins - metabolism (366) 366
smad2 protein - metabolism (366) 366
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (12946) 12946
Chinese (913) 913
Japanese (247) 247
Korean (93) 93
French (48) 48
German (35) 35
Polish (21) 21
Portuguese (15) 15
Spanish (15) 15
Russian (9) 9
Czech (6) 6
Turkish (6) 6
Persian (3) 3
Breton (2) 2
Swedish (2) 2
Arabic (1) 1
Belarusian (1) 1
Catalan (1) 1
Dutch (1) 1
Hungarian (1) 1
Indonesian (1) 1
Lithuanian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0168363
Transforming growth factor-beta (TGF-beta) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-beta signals... 
BREAST-CANCER | FIBROSIS | EPITHELIAL-CELL PROLIFERATION | GROWTH-FACTOR-BETA | MULTIDISCIPLINARY SCIENCES | NA+/K+-ATPASE | SMOOTH-MUSCLE-CELLS | PULMONARY MYOFIBROBLAST DIFFERENTIATION | FIBROBLASTS | CARDIAC-GLYCOSIDES | DIGITALIS | Phosphorylation | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Signal Transduction | Down-Regulation | Humans | Cells, Cultured | Lung - cytology | Sodium-Potassium-Exchanging ATPase - metabolism | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Fibroblasts - cytology | Lung - metabolism | Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Vimentin | Transcription factors | Smad protein | Mesenchyme | Laboratories | Epithelial cells | Transforming growth factor-b | Genes | Lung cancer | Ouabain | Transforming growth factor-a | Critical care | Smooth muscle | Lipids | Biology | Metastasis | Kinases | Cancer therapies | Fibronectin | Receptors | Cell growth | Actin | Rodents | Smad2 protein | Fibroblasts | Inhibition | Alveoli | Growth factors | Muscles | Breast cancer | Biophysics | Gene expression | Na+/K+-exchanging ATPase | Membrane proteins | Medicine | Signaling | Sodium | Potassium | Binding sites | Apoptosis
Journal Article
Aging cell, ISSN 1474-9726, 2004, Volume 3, Issue 6, pp. 379 - 389
Summary Osteoblasts and adipocytes originate from a common progenitor, which arises from bone marrow mesenchymal stroma/stem cells (mMSC). Aging causes a... 
marrow stem cells | PPAR‐γ | aging | osteoblast | TGF‐β/BMP | adipocyte | Aging | Osteoblast | Adipocyte | TGF-β/BMP | Marrow stem cells | PPAR-γ | BMP | TGF-β
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2004, Volume 165, Issue 5, pp. 723 - 734
Transforming growth factor-βs (TGF-β) are secreted as inactive complexes containing the TGF-β, the TGF-β propeptide, also called the latency-associated protein... 
Polymerase chain reaction | Cell growth | Complementary DNA | Carrier proteins | Cell lines | Amino acids | Mathematical functions | CHO cells | Cells | Integrins | Latent TGF-β | TGF-β | Integrin | LTBP | LTBP; TGF-β; integrin; αvβ6; latent TGF-β
Journal Article
Nature genetics, ISSN 1546-1718, 2014, Volume 46, Issue 5, pp. 457 - 461
Journal Article
Chest, ISSN 0012-3692, 2018, Volume 153, Issue 4, pp. 851 - 862
The expression and localization of transforming growth factor-β (TGF-β) pathway proteins in different compartments of the lower airways of patients with stable... 
airway inflammation | TGF-β | SMAD | autoimmunity | BAMBI | CTGF | DOWN-REGULATION | BINDING-PROTEINS | PATHOGENESIS | TGF-beta | OBSTRUCTIVE PULMONARY-DISEASE | GROWTH-FACTOR-BETA | RESPIRATORY SYSTEM | TRANSFORMING GROWTH-FACTOR-BETA-1 | EMPHYSEMA | GENE-EXPRESSION | ASTHMA | CIGARETTE-SMOKE | CRITICAL CARE MEDICINE | Biomarkers - metabolism | Immunohistochemistry | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Male | Transforming Growth Factor beta3 - metabolism | Case-Control Studies | Bronchi - metabolism | Female | Signal Transduction - physiology | Aged | Lung - metabolism | Membrane Proteins - metabolism | Macrophages, Alveolar - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Respiratory Mucosa - metabolism | Smad Proteins - metabolism | Lung diseases, Obstructive | Control | Usage | Smokers | Diagnosis | Transforming growth factors | Health aspects | Smoking | PI3K, phosphoinositide 3-kinase | CCN2, connective tissue growth factor | ECM, extracellular matrix | TGIF, 5′-TG-3′-interacting factor | BAMBI, bone morphogenetic proteins and activin membrane-bound inhibitor | TGFBI, transforming growth factor-β-induced protein | TRAP-1, transforming growth factor-β receptor-associated binding protein | TGF-βR, TGF-β receptor | SMAD, small mother against decapentaplegic | TGF, transforming growth factor | LLC, large latent complex | LTBP, latent transforming growth factor-β binding protein | BMP, bone morphogenetic protein | LAP, latency-associated peptide | MAPK, mitogen-activated protein kinase
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 04/2016, Volume 117, Issue 4, pp. 860 - 871
ABSTRACT Regular consumption of moderate amounts of ethanol has important health benefits on atherosclerotic cardiovascular disease (ASCVD). Overindulgence can... 
CANONICAL TGF‐β SIGNALING | TGF‐β RECEPTORS | TGF‐β ENHANCER | NON‐LIPID RAFT MICRODOMAINS | TGF-β RECEPTORS | NON-LIPID RAFT MICRODOMAINS | CANONICAL TGF-β SIGNALING | TGF-β ENHANCER | TGF-beta ENHANCER | DI-LEUCINE FAMILY | TGF-beta RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALCOHOL-CONSUMPTION | CONSTITUTIVE ENDOCYTOSIS | CELL BIOLOGY | SIGNAL-TRANSDUCTION | GROWTH-FACTOR-BETA | CANONICAL TGF-beta SIGNALING | LIPID RAFTS | MEDIATED ENDOCYTOSIS | DEPENDENT ENDOCYTOSIS | ASSOCIATION | PLASMA-CONCENTRATION | Cytoplasmic Vesicles - drug effects | Cell Fractionation | Phosphorylation | Receptors, Transforming Growth Factor beta - genetics | Epithelial Cells - metabolism | Luciferases - metabolism | Membrane Microdomains - metabolism | Epithelial Cells - drug effects | Caveolae - drug effects | Cytoplasmic Vesicles - chemistry | Lung - cytology | Luciferases - genetics | Dose-Response Relationship, Drug | Protein Isoforms - metabolism | Smad2 Protein - genetics | Cytoplasmic Vesicles - metabolism | Lung - metabolism | Epithelial Cells - cytology | Mink | Genes, Reporter | Signal Transduction | Caveolae - metabolism | Gene Expression Regulation | Smad2 Protein - metabolism | Caveolin 1 - genetics | Membrane Microdomains - chemistry | Caveolae - chemistry | Caveolin 1 - metabolism | Ethanol - pharmacology | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Membrane Microdomains - drug effects | Lung - drug effects | Transforming Growth Factor beta - metabolism | Cell Line, Transformed | Protein Isoforms - genetics
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2012, Volume 445, Issue 3, pp. 403 - 411
N-linked 21ycosylation is a critical determinant of protein structure and function, regulating processes such as protein folding, stability and localization,... 
Type II transforming growth factor β receptor (TβRII) | N-linked glycosylation | Cell surface transport | Transforming growth factor β sensitivity (TGF-β sensitivity) | Transforming growth factor β signalling (TGF-β signalling) | transforming growth factor beta signalling (TGF-beta signalling) | OLIGOSACCHARIDES | MEMBRANE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | MECHANISMS | type II transforming growth factor beta receptor (T beta RII) | transforming growth factor beta sensitivity (TGF-beta sensitivity) | CELL-SURFACE TRANSPORT | BIOSYNTHESIS | TUMOR-SUPPRESSOR | cell surface transport | PROTEINS | EXPRESSION | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - chemistry | Humans | Molecular Sequence Data | Glycosylation - drug effects | HEK293 Cells | Conserved Sequence | Cell Membrane - metabolism | Protein-Serine-Threonine Kinases - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Alkaloids - pharmacology | Mutagenesis, Site-Directed | Protein-Serine-Threonine Kinases - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Hep G2 Cells | Sequence Homology, Amino Acid | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Protein-Serine-Threonine Kinases - chemistry | HeLa Cells | Transforming Growth Factor beta - metabolism | Amino Acid Substitution | Asparagine - chemistry | transforming growth factor β sensitivity (TGF-β sensitivity) | KIF, kifunensine | dNG, deficient N-linked glycosylation | TβRII, type II TGF-β receptor | WT, wild-type | Tun, tunicamycin | FBS, fetal bovine serum | TGF-β, transforming growth factor β | Endo H, endoglycosidase H | HEK, human embryonic kidney | DAPI, 4′,6-diamidino-2-phenylindole | type II transforming growth factor β receptor (TβRII) | PNGase F, peptide N-glycosidase F | PEI, polyethyleneimine | GlcNAc, N-acetylglucosamine | transforming growth factor β signalling (TGF-β signalling) | TβRI, type I TGF-β receptor | ER, endoplasmic reticulum | PDI, protein disulfide-isomerase | RT, room temperature
Journal Article
The journal of histochemistry and cytochemistry, ISSN 1551-5044, 2016, Volume 64, Issue 3, pp. 157 - 167
Transforming growth factor-beta1 (TGF-β1), a key member in the TGF-β superfamily, plays a critical role in the development of hepatic fibrosis. Its expression... 
TGF-β/SMAD | miRNAs | hepatic fibrosis | Epithelial-myofibroblast transition | Liver Cirrhosis - pathology | Signal Transduction | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Humans | Liver Cirrhosis - metabolism | TGF-β | Review | SMAD
Journal Article
Translational Research, ISSN 1931-5244, 2015, Volume 165, Issue 4, pp. 512 - 530
Renal fibrosis is the hallmark of virtually all progressive kidney diseases and strongly correlates with the deterioration of kidney function. The... 
Internal Medicine | activating transcription factor 2 | inhibitor of kappa B | activator protein-1 | unilateral ureteral obstruction | AP-1 | CTGF | ANG II | TGF-β-inducible gene | TβRII | angiotensin-converting enzyme | bone morphogenetic protein receptor | Monocyte chemoattractant protein-1 | idiopathic pulmonary fibrosis | PPARγ | ARB | plasminogen activator inhibitor-1 | TAK1-binding protein 1 | receptor-regulated Smads | angiotensin II receptor blocker | MAPK kinase kinase kinase | stz | CCL2-CCR2 | uterine sensitization-associated gene-1 | ESRD | chronic kidney disease | TSP 1 | nuclear factor kappa B | acute tubular necrosis | mitogen-activated protein kinase | Peroxisome proliferator-activated receptor γ | TrKA | A Study of Cardiovascular Events in Diabetes | TAK1 | USAG-1 | ASCEND | transforming growth factor β1 | von Willebrand factor | βig-h3 | FSGS | MKKK | heparan sulfate proteoglycan | CCR1 | ACE | HSPG | BMP | MKK | bone morphogenetic protein | ECM | endothelin | thrombospondin type 1 | tyrosine receptor kinase A | ETA | focal segmental glomerular sclerosis | ATN | phosphodiesterase | TAB1 | ATF 2 | extracellular matrix | Kielin/chordin-like protein | JNK | RAAS | small interfering RNA | LRP | lipoprotein receptor-related protein | NF-κB | renin-angiotensin-aldosterone system | BMPR | PAI-1 | LC3 | TGF-β type I receptor | c-Jun N-terminal kinase | TβRI | IGF-1 | end-stage renal disease | MAPK | EMT | UUO | epithelial-to-mesenchymal transition | connective tissue growth factor | streptozotocin | Nox | ROS | mitogen-activated protein kinase kinase | insulin-like growth factor 1 | nicotinamide adenine dinucleotide phosphate oxidase | MCP-1 | tumor necrosis factor α | estimated glomerular filtration rate | vWF | CC motif chemokine ligand 2-CC receptor type 2 | TGF-β type II receptor | IκB | microtubule-associated protein 1 light chain 3 | PDE | TGF-β-activated kinase 1 | reactive oxygen species | CC receptor type 1 | Angiotensin II | CKD | endothelin A receptor | eGFR | VEGF | siRNA | TNF-α | R-Smads | vascular endothelial growth factor | KCP | TGF-β1 | IPF | MEDICINE, RESEARCH & EXPERIMENTAL | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | ANGIOTENSIN-ALDOSTERONE SYSTEM | DIABETIC-NEPHROPATHY | MATRIX GENE-EXPRESSION | RENAL FIBROSIS | MEDICINE, GENERAL & INTERNAL | TISSUE GROWTH-FACTOR | TRANSFORMING GROWTH-FACTOR-BETA-1 | BONE MORPHOGENETIC PROTEIN-7 | TGF-BETA ANTIBODY | MEDICAL LABORATORY TECHNOLOGY | IDIOPATHIC PULMONARY-FIBROSIS | Fibrosis - drug therapy | Signal Transduction | Humans | Transforming Growth Factor beta1 - metabolism | Drug Design | Transforming Growth Factor beta1 - genetics | Fibrosis - pathology | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - pathology | Oxidases | Phosphates | Niacinamide | Medical colleges | Development and progression | Transforming growth factors | Homeopathy | Materia medica and therapeutics | Purines | Chronic kidney failure | Nitric oxide | Therapeutics | Angiotensin | Bone morphogenetic proteins | Health aspects | bone morphogenic protein-7 | autophagy | transforming growth factor-β | NADPH oxidase | tumor necrosis factor-α | Kidney fibrosis | endothelin-1 | C-C motif chemokine | chemokine receptor
Journal Article