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AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 01/2017, Volume 187, Issue 1, pp. 156 - 162
IL-34 is a proinflammatory cytokine implicated in rheumatoid arthritis (RA). The current study aimed to assess the IL-34 expression in response to two members... 
TGF-BETA | PATHWAY | PATHOLOGY
Journal Article
Human Reproduction, ISSN 0268-1161, 2010, Volume 25, Issue 1, pp. 101 - 109
Journal Article
SCIENCE, ISSN 0036-8075, 07/2007, Volume 317, Issue 5835, pp. 256 - 260
The cytokine transforming growth factor-beta (TGF-beta) converts naive T cells into regulatory T (Treg) cells that prevent autoimmunity. However, in the... 
TGF-BETA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GENERATION | FOXP3
Journal Article
SCIENCE, ISSN 0036-8075, 11/2018, Volume 362, Issue 6417, pp. 952 - 952
Transforming growth factor-beta 1 (TGF-beta 1) is one of very few cytokines produced in a latent form, requiring activation to exert any of its vastly diverse... 
TGF-BETA | MULTIDISCIPLINARY SCIENCES | SURFACE | PROTEINS
Journal Article
SCIENCE, ISSN 0036-8075, 11/2009, Volume 326, Issue 5955, pp. 986 - 991
Distinct classes of protective immunity are guided by activation of STAT transcription factor family members in response to environmental cues. CD4(+)... 
PATHWAYS | HOMEOSTASIS | TGF-BETA | PROGRAMS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ROR-GAMMA | DIFFERENTIATION | INDUCTION | IL-23 | FOXP3
Journal Article
11/2013
From the simplest unicellular organisms to complex metazoans, cell polarity is a widespread characteristic that is essential for almost every aspect of... 
TGF-beta | Reprogramming | 0379 | Hippo | Polarity | 0307 | Pluripotency | Cancer
Dissertation
by Ye, XZ and Xu, SL and Xin, YH and Yu, SC and Ping, YF and Chen, L and Xiao, HL and Wang, B and Yi, L and Wang, QL and Jiang, XF and Yang, L and Zhang, P and Qian, C and Cui, YH and Zhang, X and Bian, XW
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 07/2012, Volume 189, Issue 1, pp. 444 - 453
The invasion of malignant glioma cells into the surrounding normal brain tissues is crucial for causing the poor outcome of this tumor type. Recent studies... 
INITIATING CELLS | MIGRATION | TGF-BETA | ANGIOGENESIS | MICROENVIRONMENT | MACROPHAGES | BONE | IMMUNOLOGY | CANCER | T-CELLS | PROGRESSION
Journal Article
IMMUNITY, ISSN 1074-7613, 08/2009, Volume 31, Issue 2, pp. 331 - 341
Th17 cells, CD4(+) T cells that secrete interleukin-17 (IL-17), are pathogenic in autoimmune diseases and their development and expansion is driven by the... 
GROWTH-FACTOR-BETA | T(H)17 CELLS | TGF-BETA | MULTIPLE-SCLEROSIS | INFLAMMATION | PROINFLAMMATORY IL-17(+) | RECEPTOR | CYTOKINE | DIFFERENTIATION | IMMUNOLOGY | CUTTING EDGE
Journal Article
11/2012
Medulloblastoma (MB) is the most common pediatric malignant brain tumor. Little is known about aggressive forms of this disease. In order to identify pathways... 
smad3 | TGF-beta | 0992 | medulloblastoma | cerebellar development | 0571 | prognosis
Dissertation
NATURE, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 518 - 518
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. Although the underlying genetic basis of this class of... 
OSMOTIC-STRESS | TGF-BETA | MULTIPLE-SCLEROSIS | GENE | THREONINE PROTEIN-KINASE | SGK | MULTIDISCIPLINARY SCIENCES | P38 MAPK | TRANSCRIPTIONAL TARGET | T-CELLS | CYTOKINE GM-CSF
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2014, Volume 15, Issue 7, pp. 676 - 686
The molecular checkpoints that drive inflammatory bowel diseases are incompletely understood. Here we found more T cells expressing the transcription factor... 
TH9 CELLS | TIGHT JUNCTIONS | IMMUNITY | INFLAMMATORY-BOWEL-DISEASE | TGF-BETA | CROHNS-DISEASE | ULCERATIVE-COLITIS | CYTOKINE | DIFFERENTIATION | IMMUNOLOGY | LUNG INFLAMMATION
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 10/2012, Volume 13, Issue 10, pp. 991 - 999
Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) are often present at the sites of tissue inflammation in autoimmune diseases, which has led to... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | MULTIPLE-SCLEROSIS | ARYL-HYDROCARBON RECEPTOR | IFN-GAMMA | TRANSFORMING GROWTH-FACTOR-BETA-1 | IL-17-PRODUCING T-CELLS | IMMUNOLOGY | INTERLEUKIN-7 RECEPTOR | CYTOKINE GM-CSF | TH17 CELLS
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2016, Volume 17, Issue 5, pp. 545 - 555
Oral tolerance prevents pathological inflammatory responses to innocuous foreign antigens by peripheral regulatory T cells (pT(reg) cells). However, whether a... 
REGULATORY FACTOR-4 | TGF-BETA | INFLAMMATION | MACROPHAGES | RETINOIC-ACID | IN-VIVO | ORAL TOLERANCE | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | LINEAGE
Journal Article
CELL, ISSN 0092-8674, 09/2011, Volume 146, Issue 5, pp. 772 - 784
T cell differentiation into distinct functional effector and inhibitory subsets is regulated, in part, by the cytokine environment present at the time of... 
EFFECTOR | ACTIVATION | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR FOXP3 | ROR-GAMMA | HELPER-CELLS | REGULATORY T-CELLS | DIFFERENTIATION | LINEAGE | CUTTING EDGE | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 04/2012, Volume 484, Issue 7395, pp. 514 - U139
IL-17-producing CD4(+) T helper cells (T(H)17) have been extensively investigated in mouse models of autoimmunity(1). However, the requirements for... 
HYPER-IGE SYNDROME | GROWTH-FACTOR-BETA | TGF-BETA | MEMORY | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | HELPER-CELLS | CD4(+) T-CELLS | DIFFERENTIATION | TH17 CELLS | PROSTAGLANDIN-E2
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2008, Volume 9, Issue 6, pp. 650 - 657
Interleukin 17 (IL-17)-producing T helper 17 cells (T-H-17 cells) have been described as a T helper cell subset distinct from T helper type 1 (T(H)1) and T(H)2... 
T(H)17 CELLS | TGF-BETA | DENDRITIC CELLS | INFLAMMATION | IL-17 | DIFFERENTIATION | IMMUNOLOGY | IL-23 | AUTOIMMUNE ENCEPHALOMYELITIS | T-HELPER-CELLS | TH17 CELLS
Journal Article
by Ma, SB and Cheng, Q and Cai, YF and Gong, HL and Wu, Y and Yu, X and Shi, LY and Wu, DP and Dong, C and Liu, HY
CANCER RESEARCH, ISSN 0008-5472, 04/2014, Volume 74, Issue 7, pp. 1969 - 1982
Interleukin (IL)-17A is expressed in the tumor microenvironment where it appears to contribute to tumor development, but its precise role in tumor immunity... 
IMMUNITY | TGF-BETA | INTERLEUKIN-17 | ANGIOGENESIS | ONCOLOGY | DISTINCT | MICE | INFECTION | SUPPRESSOR-CELLS | MYELOID CELLS | EXPRESSION
Journal Article
Kidney International, ISSN 0085-2538, 07/2019, Volume 96, Issue 1, pp. 139 - 158
Transforming growth factor–β (TGF-β) is known to play a critical role in the pathogenesis of many progressive podocyte diseases. However, the molecular... 
TGF-beta | fibrosis | focal segmental glomerulosclerosis | glomerulonephritis | glomerulus | podocyte
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 10/2007, Volume 179, Issue 7, pp. 4313 - 4317
STAT3 activation has been observed in several autoimmune diseases, suggesting that STAT3-mediated pathways promote pathologic immune responses. We provide in... 
ENCEPHALOMYELITIS | PATHWAYS | TGF-BETA | INTERLEUKIN-17 | INFLAMMATION | REGULATORY T-CELLS | CYTOKINE | GENERATION | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION
Journal Article
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